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The map label for this gene is aspA

Identifier: 123967779

GI number: 123967779

Start: 225484

End: 226389

Strand: Direct

Name: aspA

Synonym: A9601_02421

Alternate gene names: NA

Gene position: 225484-226389 (Clockwise)

Preceding gene: 123967776

Following gene: 123967781

Centisome position: 13.5

GC content: 31.79

Gene sequence:

>906_bases
ATGACTGTTCAAAGAATACTTATCGTTTCAGGCACTCATGGGAATGAAATTAATCCTGTTTGGGCGGTTAAACAATTTAA
TAGAGAGGAAAATAGTTTAAAACATGGTATTGAGTATGAATACATCATAGGTAATCCTGTTGCCTATGAAAAAGGGTGCA
GATATATAGATGTAGATTTAAATAGATCTTTTAAAGAAAGTGAGAATTGTGATCAACAAAAGAATAGCTTTTATGAAACA
AATAGAGCCAATTTTTTGTTAGATGAATTTGGAATTGACGGATCTAAACCCTGTCAAATTGTAATCGATTTGCATACTAC
TACTGCAAATATGGGAACTAGTATTGTTTTGTATGGGAGGAGATTCAAAGATTTTTGTTTAGCTGCGTTACTGCAGAACA
AATTTGGATTGCCTATTTATTTGCACGAAAAAGATAAAGCTCAAACTGGCTTTCTTGTAGAAGCTTGGCCATGTGGTCTA
GTTATTGAAATAGGAGCTGTAGCACAAAATTTTTATGATCCAAAAATCATAGATAGATTCTCTCTAATAATTAGCTCCCT
AAGGGAAGAGATAGATAAATTAAAAAATAACCTTATAGAACTCCCAAAGGAATTGGTTGTTTATGTTCATCAAGGAAGCA
TAGATTATCCAAGAGATAAAAAAGGAGTTATTGATGGTCTAATTCATCCTGAGAGAATAAATCAAGATTGGAAAATGATT
AAAAAAGGAGATCCATTATTTCTTGATAGCCAAGGAATAGTTCACAAATATGACGGAGACCAATTGATTTGGCCTGTTTT
TATTGGAGAAGTTGCTTATAAGGAAAAAAATATTGCCATGAGTTACACAAAAAAAGAAGTTATTTGTTCCAAAAAACAAT
GGGTTCAAGATTTTGAAAGTCTTTAA

Upstream 100 bases:

>100_bases
GCAAAGCCATTCATTAGTTGAGTCCAAAACCAAAACCAGAATTTTTTGGAGGCCATAATAAGGTGTCTATTTTGCATAAA
ATTTTATTTTTAAAGAAAAA

Downstream 100 bases:

>100_bases
ATTAAGAAACCGGAACAATAAATCATTGAAAACTAATAAGGATTTTTTATTTAATAGATAATTTTATTTAATGTTCAATA
CTTTAATTTTTTTTACTAAC

Product: aspartoacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTVQRILIVSGTHGNEINPVWAVKQFNREENSLKHGIEYEYIIGNPVAYEKGCRYIDVDLNRSFKESENCDQQKNSFYET
NRANFLLDEFGIDGSKPCQIVIDLHTTTANMGTSIVLYGRRFKDFCLAALLQNKFGLPIYLHEKDKAQTGFLVEAWPCGL
VIEIGAVAQNFYDPKIIDRFSLIISSLREEIDKLKNNLIELPKELVVYVHQGSIDYPRDKKGVIDGLIHPERINQDWKMI
KKGDPLFLDSQGIVHKYDGDQLIWPVFIGEVAYKEKNIAMSYTKKEVICSKKQWVQDFESL

Sequences:

>Translated_301_residues
MTVQRILIVSGTHGNEINPVWAVKQFNREENSLKHGIEYEYIIGNPVAYEKGCRYIDVDLNRSFKESENCDQQKNSFYET
NRANFLLDEFGIDGSKPCQIVIDLHTTTANMGTSIVLYGRRFKDFCLAALLQNKFGLPIYLHEKDKAQTGFLVEAWPCGL
VIEIGAVAQNFYDPKIIDRFSLIISSLREEIDKLKNNLIELPKELVVYVHQGSIDYPRDKKGVIDGLIHPERINQDWKMI
KKGDPLFLDSQGIVHKYDGDQLIWPVFIGEVAYKEKNIAMSYTKKEVICSKKQWVQDFESL
>Mature_300_residues
TVQRILIVSGTHGNEINPVWAVKQFNREENSLKHGIEYEYIIGNPVAYEKGCRYIDVDLNRSFKESENCDQQKNSFYETN
RANFLLDEFGIDGSKPCQIVIDLHTTTANMGTSIVLYGRRFKDFCLAALLQNKFGLPIYLHEKDKAQTGFLVEAWPCGLV
IEIGAVAQNFYDPKIIDRFSLIISSLREEIDKLKNNLIELPKELVVYVHQGSIDYPRDKKGVIDGLIHPERINQDWKMIK
KGDPLFLDSQGIVHKYDGDQLIWPVFIGEVAYKEKNIAMSYTKKEVICSKKQWVQDFESL

Specific function: Unknown

COG id: COG2988

COG function: function code E; Succinylglutamate desuccinylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AspA/AstE family. Aspartoacylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557335, Length=299, Percent_Identity=33.7792642140468, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI189339202, Length=299, Percent_Identity=33.7792642140468, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI18087825, Length=292, Percent_Identity=29.7945205479452, Blast_Score=128, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016708
- InterPro:   IPR007036 [H]

Pfam domain/function: PF04952 AstE_AspA [H]

EC number: =3.5.1.15 [H]

Molecular weight: Translated: 34646; Mature: 34515

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQRILIVSGTHGNEINPVWAVKQFNREENSLKHGIEYEYIIGNPVAYEKGCRYIDVDL
CCCEEEEEEECCCCCCCCEEHHHHHHCCHHHHHHCCCEEEEEECCCEEHHHCCEEEEEEC
NRSFKESENCDQQKNSFYETNRANFLLDEFGIDGSKPCQIVIDLHTTTANMGTSIVLYGR
CCCCCCCCCCCHHHHHHHHCCCCCEEEHHHCCCCCCCEEEEEEEEECCCCCCCEEEEECC
RFKDFCLAALLQNKFGLPIYLHEKDKAQTGFLVEAWPCGLVIEIGAVAQNFYDPKIIDRF
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCEEEEECHHHHHCCCHHHHHHH
SLIISSLREEIDKLKNNLIELPKELVVYVHQGSIDYPRDKKGVIDGLIHPERINQDWKMI
HHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCHHHCCCCHHHCCCCHHHH
KKGDPLFLDSQGIVHKYDGDQLIWPVFIGEVAYKEKNIAMSYTKKEVICSKKQWVQDFES
HCCCCEEEECCCCEEEECCCEEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
TVQRILIVSGTHGNEINPVWAVKQFNREENSLKHGIEYEYIIGNPVAYEKGCRYIDVDL
CCEEEEEEECCCCCCCCEEHHHHHHCCHHHHHHCCCEEEEEECCCEEHHHCCEEEEEEC
NRSFKESENCDQQKNSFYETNRANFLLDEFGIDGSKPCQIVIDLHTTTANMGTSIVLYGR
CCCCCCCCCCCHHHHHHHHCCCCCEEEHHHCCCCCCCEEEEEEEEECCCCCCCEEEEECC
RFKDFCLAALLQNKFGLPIYLHEKDKAQTGFLVEAWPCGLVIEIGAVAQNFYDPKIIDRF
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCEEEEECHHHHHCCCHHHHHHH
SLIISSLREEIDKLKNNLIELPKELVVYVHQGSIDYPRDKKGVIDGLIHPERINQDWKMI
HHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCHHHCCCCHHHCCCCHHHH
KKGDPLFLDSQGIVHKYDGDQLIWPVFIGEVAYKEKNIAMSYTKKEVICSKKQWVQDFES
HCCCCEEEECCCCEEEECCCEEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA