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The map label for this gene is ndhI [H]

Identifier: 123967714

GI number: 123967714

Start: 164241

End: 164867

Strand: Reverse

Name: ndhI [H]

Synonym: A9601_01771

Alternate gene names: 123967714

Gene position: 164867-164241 (Counterclockwise)

Preceding gene: 123967715

Following gene: 123967713

Centisome position: 9.87

GC content: 31.9

Gene sequence:

>627_bases
ATGAAAAATTTTCTTCAACAAATAAATAGCTATATCAAAGAAGCATTTAATGCTGGTAAATATTTATATAATGGCTTATC
AGTAACTTTTGATCATCTTCGAAGAAGACCTGTTACAGTCCAATATCCATATGAAAAATTAATACCTTCTGAGAGATATA
GAGGAAGAATACATTATGAATTTGATAAATGTATTGCTTGTGAAGTTTGCGTGAGAGTTTGCCCCATAAATCTACCAGTT
GTTGATTGGGTAATGAATAAAGAAACTAAAAAAAAGGAACTTAGAAATTACTCTATAGACTTTGGAGTTTGTATATTTTG
CGGAAATTGTGTTGAATATTGTCCAACTAATTGTCTTTCTATGACCGAAGAATATGAATTAGCTACTTTTGACAGACACA
ATCTAAATTTTGATAATGTCGCACTTGGTAGGTTACCTACAAACGTCACAACAGATCCTTCAGTTAAACCTCTAAGAGAA
CTTGCCTATCTTCCTAAAGGTGTCATGGACCCTCATGAAATCCCAGCTTCAGATACTAGAGTTGGTAAATTACCAGAAGA
AGTCTATGATTGGATGAGGCCAGAATCCAATAAAAATAAAGATAAAGTTTCTAATTCAAACAATTAA

Upstream 100 bases:

>100_bases
AACTTGCTTTTCCGCAATTCTTTGGTGGTTAAACTTAAGTAAAAATACTTAAATTTAAAATTAATCCACTAAAATAAAAT
AACTAAGTAAATTCTTCAAA

Downstream 100 bases:

>100_bases
TTTCCATTAATTTATGTCCATTGCAATAACAACTCAAATTATTTGTTTTACAGTTTTATCTTTAGTTATCCTTATCGGAG
CACTTGGTGTTGTATTACTC

Product: NADH dehydrogenase subunit I

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit I; NDH-1 subunit I; NDH-I [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKNFLQQINSYIKEAFNAGKYLYNGLSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPV
VDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRE
LAYLPKGVMDPHEIPASDTRVGKLPEEVYDWMRPESNKNKDKVSNSNN

Sequences:

>Translated_208_residues
MKNFLQQINSYIKEAFNAGKYLYNGLSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPV
VDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRE
LAYLPKGVMDPHEIPASDTRVGKLPEEVYDWMRPESNKNKDKVSNSNN
>Mature_208_residues
MKNFLQQINSYIKEAFNAGKYLYNGLSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPV
VDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRE
LAYLPKGVMDPHEIPASDTRVGKLPEEVYDWMRPESNKNKDKVSNSNN

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=126, Percent_Identity=31.7460317460317, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1789075, Length=103, Percent_Identity=32.0388349514563, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788617, Length=117, Percent_Identity=31.6239316239316, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555194, Length=126, Percent_Identity=30.1587301587302, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17864306, Length=126, Percent_Identity=30.952380952381, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR004497
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: 1.6.5.3

Molecular weight: Translated: 24191; Mature: 24191

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFLQQINSYIKEAFNAGKYLYNGLSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYE
CHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCCEEECCHHHCCCCHHHCCCEEEH
FDKCIACEVCVRVCPINLPVVDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLS
HHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHCCHHHHCCCHHHH
MTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRELAYLPKGVMDPHEIPASDTR
HHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
VGKLPEEVYDWMRPESNKNKDKVSNSNN
CCCCHHHHHHHHCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MKNFLQQINSYIKEAFNAGKYLYNGLSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYE
CHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCCEEECCHHHCCCCHHHCCCEEEH
FDKCIACEVCVRVCPINLPVVDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLS
HHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHCCHHHHCCCHHHH
MTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRELAYLPKGVMDPHEIPASDTR
HHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
VGKLPEEVYDWMRPESNKNKDKVSNSNN
CCCCHHHHHHHHCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA