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The map label for this gene is ppnK [H]

Identifier: 123967711

GI number: 123967711

Start: 162368

End: 163279

Strand: Reverse

Name: ppnK [H]

Synonym: A9601_01741

Alternate gene names: 123967711

Gene position: 163279-162368 (Counterclockwise)

Preceding gene: 123967712

Following gene: 123967710

Centisome position: 9.78

GC content: 29.39

Gene sequence:

>912_bases
ATGAAACTTTCATTAGTGCTTATTGTATATCGTTCAGATAGTTCTATTGCTCAAGAGGCTTCTCAATTCTGTGAAGAGGT
CCTCAAAGCTAAAAATATAAAATCAAAAATAATTGAAAGTGATTTTTATAAAGATGAAATTGAAAAATATTTTTGCAATT
TAGAATTAAGACCAAATATTGGCATAGTTCTTGGTGGAGATGGAACCTTTCTAAAATGTGCAAATGCTTTATCTGATTAT
GATATTCCATTGTTGAGTATTAATATTGGTGGTAATTTGGGTTTTCTTACGCAAGAAAAAGATTTTTTGTTCGATAAATC
TTTTATTGAAATTCTTGAAAACGAAGAATATAAAATTGACTTTCGTAATAGATTAAATTGTAAAGTTTGTATTAATGGGA
CAAGTTCTGAAAAAAAGATTATAAAAAGCTACGATGCCTTAAATGATTTTTATTTTAAATCTGTTGAAGGAGACATTTCT
CCAACCAACCAAATACAAATTGAAATAGATAACGAGAAGGTTAATGAATACAAAGGTGATGGATTAATTATATCTACATC
TACTGGTTCGACAGCCTACTCAATGGCCGCAGGGGGGCCAATTGTCCACCCTAGTATTGATGCAATGATAATTAACCCTA
TATGCCCGATGAGTTTAGCTAGTAGACCAATAGTTATACCTAATACAAGTAAGGTAATCATAAAACCTGTAAAAAAAAGT
AAAGGGGGAATTAAATTATGGAGAGACGGTTCAAAATGTATGACCATTAAGGAAAATTATTATTGTGAGATCATAAAAGG
TCAATCACCTTGCAAAATAATAAAGTTTAAAAAAAGCACAAGCTACTATAATACCCTAATAAAAAAACTAGATTGGAAAG
GTGATTTATCTCAAAAAAATTTCAAAAATTAA

Upstream 100 bases:

>100_bases
AGAAGCAGCAGTTGGATTAGCTATCTTATTATCCCTTTATAGGAATAGGGTGACTGTAGATATGGAAAGTTTTAATTTAT
TAAAATGGTAAAAACACTAA

Downstream 100 bases:

>100_bases
ATGGCCTTAGAGATAGAAAGAAGATTTCTTATAAAAAATGATAATTGGAAAGAATTCATAAATAAAAAAATTTATATTGA
ACAAGGATATTTATCTAAAA

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKLSLVLIVYRSDSSIAQEASQFCEEVLKAKNIKSKIIESDFYKDEIEKYFCNLELRPNIGIVLGGDGTFLKCANALSDY
DIPLLSINIGGNLGFLTQEKDFLFDKSFIEILENEEYKIDFRNRLNCKVCINGTSSEKKIIKSYDALNDFYFKSVEGDIS
PTNQIQIEIDNEKVNEYKGDGLIISTSTGSTAYSMAAGGPIVHPSIDAMIINPICPMSLASRPIVIPNTSKVIIKPVKKS
KGGIKLWRDGSKCMTIKENYYCEIIKGQSPCKIIKFKKSTSYYNTLIKKLDWKGDLSQKNFKN

Sequences:

>Translated_303_residues
MKLSLVLIVYRSDSSIAQEASQFCEEVLKAKNIKSKIIESDFYKDEIEKYFCNLELRPNIGIVLGGDGTFLKCANALSDY
DIPLLSINIGGNLGFLTQEKDFLFDKSFIEILENEEYKIDFRNRLNCKVCINGTSSEKKIIKSYDALNDFYFKSVEGDIS
PTNQIQIEIDNEKVNEYKGDGLIISTSTGSTAYSMAAGGPIVHPSIDAMIINPICPMSLASRPIVIPNTSKVIIKPVKKS
KGGIKLWRDGSKCMTIKENYYCEIIKGQSPCKIIKFKKSTSYYNTLIKKLDWKGDLSQKNFKN
>Mature_303_residues
MKLSLVLIVYRSDSSIAQEASQFCEEVLKAKNIKSKIIESDFYKDEIEKYFCNLELRPNIGIVLGGDGTFLKCANALSDY
DIPLLSINIGGNLGFLTQEKDFLFDKSFIEILENEEYKIDFRNRLNCKVCINGTSSEKKIIKSYDALNDFYFKSVEGDIS
PTNQIQIEIDNEKVNEYKGDGLIISTSTGSTAYSMAAGGPIVHPSIDAMIINPICPMSLASRPIVIPNTSKVIIKPVKKS
KGGIKLWRDGSKCMTIKENYYCEIIKGQSPCKIIKFKKSTSYYNTLIKKLDWKGDLSQKNFKN

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=337, Percent_Identity=26.1127596439169, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1788968, Length=238, Percent_Identity=34.453781512605, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320794, Length=256, Percent_Identity=30.078125, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322509, Length=296, Percent_Identity=28.0405405405405, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325068, Length=220, Percent_Identity=30.9090909090909, Blast_Score=102, Evalue=9e-23,
Organism=Drosophila melanogaster, GI28573830, Length=295, Percent_Identity=28.135593220339, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28573826, Length=295, Percent_Identity=28.135593220339, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI161077047, Length=295, Percent_Identity=28.135593220339, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573828, Length=295, Percent_Identity=28.135593220339, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573832, Length=295, Percent_Identity=28.135593220339, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24653424, Length=328, Percent_Identity=24.6951219512195, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI20129957, Length=328, Percent_Identity=24.6951219512195, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281363321, Length=328, Percent_Identity=24.6951219512195, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281363323, Length=328, Percent_Identity=24.6951219512195, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24653422, Length=328, Percent_Identity=24.6951219512195, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 34080; Mature: 34080

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSLVLIVYRSDSSIAQEASQFCEEVLKAKNIKSKIIESDFYKDEIEKYFCNLELRPNI
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHCCEEECCCE
GIVLGGDGTFLKCANALSDYDIPLLSINIGGNLGFLTQEKDFLFDKSFIEILENEEYKID
EEEECCCCCHHHHHHHCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
FRNRLNCKVCINGTSSEKKIIKSYDALNDFYFKSVEGDISPTNQIQIEIDNEKVNEYKGD
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCHHHCCCC
GLIISTSTGSTAYSMAAGGPIVHPSIDAMIINPICPMSLASRPIVIPNTSKVIIKPVKKS
EEEEEECCCCCEEEECCCCCEECCCCCEEEECCCCCHHHCCCCEEECCCCEEEEEECCCC
KGGIKLWRDGSKCMTIKENYYCEIIKGQSPCKIIKFKKSTSYYNTLIKKLDWKGDLSQKN
CCCEEEEECCCEEEEEECCEEEEEECCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCC
FKN
CCC
>Mature Secondary Structure
MKLSLVLIVYRSDSSIAQEASQFCEEVLKAKNIKSKIIESDFYKDEIEKYFCNLELRPNI
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHCCEEECCCE
GIVLGGDGTFLKCANALSDYDIPLLSINIGGNLGFLTQEKDFLFDKSFIEILENEEYKID
EEEECCCCCHHHHHHHCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
FRNRLNCKVCINGTSSEKKIIKSYDALNDFYFKSVEGDISPTNQIQIEIDNEKVNEYKGD
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCHHHCCCC
GLIISTSTGSTAYSMAAGGPIVHPSIDAMIINPICPMSLASRPIVIPNTSKVIIKPVKKS
EEEEEECCCCCEEEECCCCCEECCCCCEEEECCCCCHHHCCCCEEECCCCEEEEEECCCC
KGGIKLWRDGSKCMTIKENYYCEIIKGQSPCKIIKFKKSTSYYNTLIKKLDWKGDLSQKN
CCCEEEEECCCEEEEEECCEEEEEECCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCC
FKN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA