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The map label for this gene is yycF [H]

Identifier: 123967688

GI number: 123967688

Start: 141911

End: 142657

Strand: Direct

Name: yycF [H]

Synonym: A9601_01511

Alternate gene names: 123967688

Gene position: 141911-142657 (Clockwise)

Preceding gene: 123967686

Following gene: 123967689

Centisome position: 8.5

GC content: 34.81

Gene sequence:

>747_bases
ATGGCTCTATCTAGTCAAACTAAAGAAACAATTCTTGTCGCAGATGACGAGGCAAGTATTAGAAGAATTTTGGAGACGCG
CCTCTCCATGATTGGTTACAAAGTAGTAACTGCAAGTGATGGTAAAGAAGCATTAAAGTTATTTAAAGATTATGAGCCTG
ATTTAGTAGTACTTGACGTTATGATGCCAAAATTAGATGGCTATGGAGTTTGTCAAGAATTAAGGAAAGATTCTGATGTT
CCCATTGTTATGTTAACTGCGTTAGGAGATGTTGCAGACAGGATAACAGGTTTAGAATTAGGTGCTGATGATTATGTTGT
TAAACCATTTAGTCCTAAGGAATTAGAAGCTAGAATTAGATGTGTTTTAAGAAGAATTGACAAAGAACAAATTCCTGGAA
TGCCTAATTCAGGATTAATTTTAGTTACTGATATAAAAATTGATACAAATCGAAGACAAGTTTTTAAAAGCGATGAGAGA
ATTAGATTAACCGGTATGGAATTTAGTCTTTTAGAGCTTTTGGTAAGTAGGTCAGGTGAGCCTTTTAGTAGAGGAGAAAT
TTTGAAGGAAGTTTGGGGATATACACCTGAGAGACATGTAGATACGAGAGTAGTCGATGTCCATATATCAAGATTAAGAT
CAAAACTTGAGGCTGATCCAGCAAATCCTGAATTGATATTAACAGCGAGGGGCACAGGATATCTTTTTCAAAGAATTGTA
GATATTACTCCTTTTGATGGTAAATAA

Upstream 100 bases:

>100_bases
TTTAATCAAGTATTAGAACTAGAATGTTTGGGATATTGCCCCTCTACAAGTTAGATTAGGATAATAATTAATTCTCTTAC
TGATTAGCTAATAGAAACAA

Downstream 100 bases:

>100_bases
ATGGGGAAAGAAAGTGCACAAAAAATTAACAAGCCCAGAGCTATCAGAAGATTAGTTATCTGGTACAAAAGAAACACGGC
TGTAACTTCATTAGTAGATA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MALSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDVMMPKLDGYGVCQELRKDSDV
PIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCVLRRIDKEQIPGMPNSGLILVTDIKIDTNRRQVFKSDER
IRLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIV
DITPFDGK

Sequences:

>Translated_248_residues
MALSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDVMMPKLDGYGVCQELRKDSDV
PIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCVLRRIDKEQIPGMPNSGLILVTDIKIDTNRRQVFKSDER
IRLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIV
DITPFDGK
>Mature_247_residues
ALSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDVMMPKLDGYGVCQELRKDSDVP
IVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCVLRRIDKEQIPGMPNSGLILVTDIKIDTNRRQVFKSDERI
RLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIVD
ITPFDGK

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=42.3076923076923, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=39.7379912663755, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=35.2422907488987, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=38.1578947368421, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=39.8230088495575, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=37.0044052863436, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=37.5, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=41.304347826087, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=33.6170212765957, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=33.1896551724138, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=33.0396475770925, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=31.7180616740088, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=32.8888888888889, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=34.1880341880342, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=39.622641509434, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790437, Length=123, Percent_Identity=34.1463414634146, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=32.5, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=37.1428571428571, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=123, Percent_Identity=34.9593495934959, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27936; Mature: 27805

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDV
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCEEEEEE
MMPKLDGYGVCQELRKDSDVPIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIR
HHCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCCHHHHHHHH
CVLRRIDKEQIPGMPNSGLILVTDIKIDTNRRQVFKSDERIRLTGMEFSLLELLVSRSGE
HHHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHCCCCEEEEECCCHHHHHHHHHCCCC
PFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIV
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
DITPFDGK
HCCCCCCC
>Mature Secondary Structure 
ALSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDV
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCEEEEEE
MMPKLDGYGVCQELRKDSDVPIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIR
HHCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCCHHHHHHHH
CVLRRIDKEQIPGMPNSGLILVTDIKIDTNRRQVFKSDERIRLTGMEFSLLELLVSRSGE
HHHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHCCCCEEEEECCCHHHHHHHHHCCCC
PFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIV
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
DITPFDGK
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]