Click here to switch to the map view.

The map label for this gene is pgm [H]

Identifier: 123967626

GI number: 123967626

Start: 92366

End: 94003

Strand: Direct

Name: pgm [H]

Synonym: A9601_00891

Alternate gene names: 123967626

Gene position: 92366-94003 (Clockwise)

Preceding gene: 123967625

Following gene: 123967627

Centisome position: 5.53

GC content: 33.09

Gene sequence:

>1638_bases
ATGAATCAAGTTAGTGTAATTAATATTAATTCTCCTTTTTTAGATCAAAAACCAGGTACTTCTGGATTAAGAAAAAGTAC
TTTAAAGTTTCAGGAAGAACATTATCTAGAAGTTTTTATTGAAGCAATTTTACAATCATTAGGAGATTTAAAAGGTTCAA
CATTAGTAGTTGGTGGTGATGGCAGATATGGCAATATTGAAGCAATAGAAAAAATTGTCCAAATATGCATTGCTCATAAA
GTTCAAAAGGTTATTGTTCCAAGATACGGATTATTATCTACTCCTGCGACCTCACATTTAATTAGAAAAGAAAACGCTAT
AGGTGGAATTATTCTTTCTGCAAGCCATAATCCTGGTGGGATTGATGGCGACTTTGGAGTGAAATTGAATATCTCGAATG
GTGGTCCAGCTCCTGAGATAATTACTAATAAGATTTTTAAGTCTTCACAATTACTAACAAGTTATAAAATTTGTAAAATT
CAATTACCTGATTTTAGTAAATATGGTACTTATCATTACGACGAAACTACCTTAGAAATTATTGATGGATTAACAGATTA
TTCTAATTTGATGGAGAAAATTTTTGACTTTGACCAAATTAGTGATTTTTTAAAAAAAGACTTCTCGTTAATCTTTGATG
CAATGAATGCGGTTACAGGTCCATATGCAAAAAATATTTTTGTTGAAAAAATGGGTCTTGCACCAGATTGTGTCATGAAT
GGTAACCCGTTAAAAGATTTTGGAGGTTTACATCCTGATCCTAATCTTACTTACGCATCCCACTTGGCTGATTTGTTACT
AAATAAAAAATCTTATAGTTTTGGTGCTGCATGCGATGGAGATGGAGATAGGAATATGATTTTAGGAAGTGGATGTTTTG
TAAATCCTAGTGATAGCCTTGCAGTTATCACTGCTAACACAAAATGTGTACCTGGTTATAAAGATGGTATTACAGGTGTG
GCACGATCCATGCCAACCAGCTCAGCGGTTGATAATGTCGCGCGAGCATTAAATATACCTTGTTTCGAGACACCTACTGG
CTGGAAGTTTTTTGGTAATCTTTTAGATTCTAATTTAATTACTTTATGTGGAGAAGAAAGTTTCGGAACAGGTAGTAATC
ATGTGAGAGAAAAAGATGGACTATGGGCAGTGTTGTATTGGTTACAAGTTTTAGCTGAGAAAAAATGTTCGGTAAGTGAT
TTGATGCAGAATCATTGGAAACAATTTGGTAGGAATTATTATTCAAGACATGATTATGAGGCAATTTCCTCAAATATTGC
TAATCAAATCTTTGGTAATCTAACTTCTTTACTCGAAAATTTAAAAGGAAATAGTTTTGCTGGCCATTTAGTTAAAGTTG
CAGATAACTTTTCATATTTAGATCCCGTTGATAATTCCATAAGTGAAAATCAAGGTTTAAGATTGGTCCTTGATGATAAT
TCTCGAGTAATTGTGCGCCTTTCTGGAACTGGAACTAAGGGTGCAACATTAAGACTTTACTTTGAGAAGTTTTTCGATCC
TCAACAGAATCTTTCGTTAAATCCTCAGATCGCTTTGAAACCTCTAATAGATGATTTAGACGCTTTATTGAACATTTCAA
AACTTACTCAAATGGAAAATCCTACAGTAATTACATAG

Upstream 100 bases:

>100_bases
TAGTGCATTATTAATTTCTTCATTATGGTTTATCGCTATGTTAAGAACTTCCGAAATGCCTCATTAATTTAGTTAGATTT
TTGAAAGTTTTCTTAAAAAT

Downstream 100 bases:

>100_bases
AATTGAAAGTAATAATTTTTTGATTTTATTTATATGCATTCAGAAAATTTATTTACTAATTATTCTCAAATAGAAAACAA
TGCACCTTTGGCAGATAAAT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MNQVSVININSPFLDQKPGTSGLRKSTLKFQEEHYLEVFIEAILQSLGDLKGSTLVVGGDGRYGNIEAIEKIVQICIAHK
VQKVIVPRYGLLSTPATSHLIRKENAIGGIILSASHNPGGIDGDFGVKLNISNGGPAPEIITNKIFKSSQLLTSYKICKI
QLPDFSKYGTYHYDETTLEIIDGLTDYSNLMEKIFDFDQISDFLKKDFSLIFDAMNAVTGPYAKNIFVEKMGLAPDCVMN
GNPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSLAVITANTKCVPGYKDGITGV
ARSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLITLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKKCSVSD
LMQNHWKQFGRNYYSRHDYEAISSNIANQIFGNLTSLLENLKGNSFAGHLVKVADNFSYLDPVDNSISENQGLRLVLDDN
SRVIVRLSGTGTKGATLRLYFEKFFDPQQNLSLNPQIALKPLIDDLDALLNISKLTQMENPTVIT

Sequences:

>Translated_545_residues
MNQVSVININSPFLDQKPGTSGLRKSTLKFQEEHYLEVFIEAILQSLGDLKGSTLVVGGDGRYGNIEAIEKIVQICIAHK
VQKVIVPRYGLLSTPATSHLIRKENAIGGIILSASHNPGGIDGDFGVKLNISNGGPAPEIITNKIFKSSQLLTSYKICKI
QLPDFSKYGTYHYDETTLEIIDGLTDYSNLMEKIFDFDQISDFLKKDFSLIFDAMNAVTGPYAKNIFVEKMGLAPDCVMN
GNPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSLAVITANTKCVPGYKDGITGV
ARSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLITLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKKCSVSD
LMQNHWKQFGRNYYSRHDYEAISSNIANQIFGNLTSLLENLKGNSFAGHLVKVADNFSYLDPVDNSISENQGLRLVLDDN
SRVIVRLSGTGTKGATLRLYFEKFFDPQQNLSLNPQIALKPLIDDLDALLNISKLTQMENPTVIT
>Mature_545_residues
MNQVSVININSPFLDQKPGTSGLRKSTLKFQEEHYLEVFIEAILQSLGDLKGSTLVVGGDGRYGNIEAIEKIVQICIAHK
VQKVIVPRYGLLSTPATSHLIRKENAIGGIILSASHNPGGIDGDFGVKLNISNGGPAPEIITNKIFKSSQLLTSYKICKI
QLPDFSKYGTYHYDETTLEIIDGLTDYSNLMEKIFDFDQISDFLKKDFSLIFDAMNAVTGPYAKNIFVEKMGLAPDCVMN
GNPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSLAVITANTKCVPGYKDGITGV
ARSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLITLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKKCSVSD
LMQNHWKQFGRNYYSRHDYEAISSNIANQIFGNLTSLLENLKGNSFAGHLVKVADNFSYLDPVDNSISENQGLRLVLDDN
SRVIVRLSGTGTKGATLRLYFEKFFDPQQNLSLNPQIALKPLIDDLDALLNISKLTQMENPTVIT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=557, Percent_Identity=50.8078994614004, Blast_Score=549, Evalue=1e-156,
Organism=Homo sapiens, GI21361621, Length=564, Percent_Identity=48.5815602836879, Blast_Score=532, Evalue=1e-151,
Organism=Homo sapiens, GI133922562, Length=556, Percent_Identity=45.5035971223022, Blast_Score=485, Evalue=1e-137,
Organism=Homo sapiens, GI290463104, Length=368, Percent_Identity=50.2717391304348, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI239743670, Length=114, Percent_Identity=44.7368421052632, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI239741729, Length=114, Percent_Identity=46.4912280701754, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535441, Length=558, Percent_Identity=47.8494623655914, Blast_Score=501, Evalue=1e-142,
Organism=Saccharomyces cerevisiae, GI6323752, Length=562, Percent_Identity=47.153024911032, Blast_Score=490, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6322722, Length=561, Percent_Identity=46.8805704099822, Blast_Score=479, Evalue=1e-136,
Organism=Drosophila melanogaster, GI17864244, Length=557, Percent_Identity=48.6535008976661, Blast_Score=523, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59842; Mature: 59842

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQVSVININSPFLDQKPGTSGLRKSTLKFQEEHYLEVFIEAILQSLGDLKGSTLVVGGD
CCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
GRYGNIEAIEKIVQICIAHKVQKVIVPRYGLLSTPATSHLIRKENAIGGIILSASHNPGG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCC
IDGDFGVKLNISNGGPAPEIITNKIFKSSQLLTSYKICKIQLPDFSKYGTYHYDETTLEI
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCHHCCCEECCCHHHHH
IDGLTDYSNLMEKIFDFDQISDFLKKDFSLIFDAMNAVTGPYAKNIFVEKMGLAPDCVMN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEC
GNPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSL
CCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCEECCCCCE
AVITANTKCVPGYKDGITGVARSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLI
EEEEECCEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEE
TLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKKCSVSDLMQNHWKQFGRNYYSRHDYE
EEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
AISSNIANQIFGNLTSLLENLKGNSFAGHLVKVADNFSYLDPVDNSISENQGLRLVLDDN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCEEEEEECC
SRVIVRLSGTGTKGATLRLYFEKFFDPQQNLSLNPQIALKPLIDDLDALLNISKLTQMEN
CEEEEEEECCCCCCCEEEEEHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
PTVIT
CCCCC
>Mature Secondary Structure
MNQVSVININSPFLDQKPGTSGLRKSTLKFQEEHYLEVFIEAILQSLGDLKGSTLVVGGD
CCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
GRYGNIEAIEKIVQICIAHKVQKVIVPRYGLLSTPATSHLIRKENAIGGIILSASHNPGG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCC
IDGDFGVKLNISNGGPAPEIITNKIFKSSQLLTSYKICKIQLPDFSKYGTYHYDETTLEI
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCHHCCCEECCCHHHHH
IDGLTDYSNLMEKIFDFDQISDFLKKDFSLIFDAMNAVTGPYAKNIFVEKMGLAPDCVMN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEC
GNPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSL
CCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCEECCCCCE
AVITANTKCVPGYKDGITGVARSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLI
EEEEECCEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEE
TLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKKCSVSDLMQNHWKQFGRNYYSRHDYE
EEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
AISSNIANQIFGNLTSLLENLKGNSFAGHLVKVADNFSYLDPVDNSISENQGLRLVLDDN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCEEEEEECC
SRVIVRLSGTGTKGATLRLYFEKFFDPQQNLSLNPQIALKPLIDDLDALLNISKLTQMEN
CEEEEEEECCCCCCCEEEEEHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
PTVIT
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]