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The map label for this gene is hit [C]

Identifier: 123967616

GI number: 123967616

Start: 82647

End: 82988

Strand: Reverse

Name: hit [C]

Synonym: A9601_00791

Alternate gene names: 123967616

Gene position: 82988-82647 (Counterclockwise)

Preceding gene: 123967617

Following gene: 123967615

Centisome position: 4.97

GC content: 28.95

Gene sequence:

>342_bases
ATGACTGAAACAACAATATTTCAAAAAATCATTAATGAAGAAATACCCTGCGATAAGCTTTATGAAGATAAGTTTTGTAT
TGCTTTTAATGATATCCAGGCACAAGCACCAGTTCATTTTTTAGTGATTCCAAAAAAGCCAATTATAAGTTTATTAGATT
GTATTGAAGAGGATGTAAATTTATTAGGGCATTTACTTTATGTGGGTAGCAAAATAGCTAAATCAAAAAATTTAACTAAT
TGGAGAACAGTAATTAATACTGGAGCAGAATCAGGACAAACAGTTTTTCATTTACATATTCATTTTTTATCTGGAAGAAA
AATGAATTGGCCTCCAGGTTAA

Upstream 100 bases:

>100_bases
ATATTATTTGTAGATAGAGTTACATCAAAAGATGATTTGAACAAAGAACTTTTAAAAGAAGGGTTTAACGAAAAAGACGT
TATCTCAATTAATTAATTTA

Downstream 100 bases:

>100_bases
AACTCTCGAAAGAAATGTTAATGGGTTATAAATAAGTAAAAACAAAATGAATACCCCAGATTCCCTAAATACAGAATCCA
AAAATTTATTCAATTTAATC

Product: HIT (histidine triad) family protein

Products: NA

Alternate protein names: ORF 1 [H]

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MTETTIFQKIINEEIPCDKLYEDKFCIAFNDIQAQAPVHFLVIPKKPIISLLDCIEEDVNLLGHLLYVGSKIAKSKNLTN
WRTVINTGAESGQTVFHLHIHFLSGRKMNWPPG

Sequences:

>Translated_113_residues
MTETTIFQKIINEEIPCDKLYEDKFCIAFNDIQAQAPVHFLVIPKKPIISLLDCIEEDVNLLGHLLYVGSKIAKSKNLTN
WRTVINTGAESGQTVFHLHIHFLSGRKMNWPPG
>Mature_112_residues
TETTIFQKIINEEIPCDKLYEDKFCIAFNDIQAQAPVHFLVIPKKPIISLLDCIEEDVNLLGHLLYVGSKIAKSKNLTNW
RTVINTGAESGQTVFHLHIHFLSGRKMNWPPG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=110, Percent_Identity=53.6363636363636, Blast_Score=131, Evalue=1e-31,
Organism=Homo sapiens, GI4885413, Length=110, Percent_Identity=51.8181818181818, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1787346, Length=111, Percent_Identity=41.4414414414414, Blast_Score=88, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17506713, Length=110, Percent_Identity=47.2727272727273, Blast_Score=120, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320078, Length=112, Percent_Identity=36.6071428571429, Blast_Score=62, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581222, Length=113, Percent_Identity=53.9823008849557, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574010, Length=113, Percent_Identity=53.9823008849557, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 12848; Mature: 12717

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTIFQKIINEEIPCDKLYEDKFCIAFNDIQAQAPVHFLVIPKKPIISLLDCIEEDVN
CCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
LLGHLLYVGSKIAKSKNLTNWRTVINTGAESGQTVFHLHIHFLSGRKMNWPPG
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TETTIFQKIINEEIPCDKLYEDKFCIAFNDIQAQAPVHFLVIPKKPIISLLDCIEEDVN
CHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
LLGHLLYVGSKIAKSKNLTNWRTVINTGAESGQTVFHLHIHFLSGRKMNWPPG
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108129; 1472710 [H]