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The map label for this gene is aroQ

Identifier: 121999115

GI number: 121999115

Start: 2562710

End: 2563156

Strand: Reverse

Name: aroQ

Synonym: Hhal_2337

Alternate gene names: 121999115

Gene position: 2563156-2562710 (Counterclockwise)

Preceding gene: 121999116

Following gene: 121999114

Centisome position: 95.7

GC content: 65.77

Gene sequence:

>447_bases
ATGCCCAAGCTGTTGTTACTCCACGGGCCCAATCTGAATCGACTGGGGACCCGCGAGCCGGAGCGCTACGGACGGCTGAC
GCTTCAGGACATCGAAACCCGCTTGCGGTCCATCTGCGACGCGGCCGGCGTGCAGTTGTGCAGCGCCCAGTCCAATCATG
AGGGCGAGCTCATCGATCGGATCCACGCCGCGGCGGATGAAGGCGTCGAGTTCATCGTCATCAATCCCGCGGCCCTGACG
CACACCAGTGTCGGTCTGCGCGACGCGCTGCTTGCCGTTGCGCTGCCGTTCATCGAGGTGCACTTGAGCAACGTCCACGC
CCGCGAGGCGTTCCGGCAACACTCTTATCTGTCCGACATCGCCGAGGGGGTGATCACCGGCCTCGGCGCGGACGGCTATG
ACTTCGCGGCCCGTGCAGCCATCCGGCGCATGGGCGGTCAGGCCTGA

Upstream 100 bases:

>100_bases
GGCGAAACGGCCGGGATTGTGTCGGGATCACCGTAAAACTAGACAATCTTCCGGCGCTCAGTCAGAATCGCGGGCGGTGC
GAGTCGGGTGAGCGCGTGTC

Downstream 100 bases:

>100_bases
ACACAGGGTTTCGTCGATCTATGGATATTCGCAAGATCAAACGTCTTATCGAGCTGCTCGACGAGTCCGGCGTCCACGAG
ATTGAGATCGCCGAGGGCGA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MPKLLLLHGPNLNRLGTREPERYGRLTLQDIETRLRSICDAAGVQLCSAQSNHEGELIDRIHAAADEGVEFIVINPAALT
HTSVGLRDALLAVALPFIEVHLSNVHAREAFRQHSYLSDIAEGVITGLGADGYDFAARAAIRRMGGQA

Sequences:

>Translated_148_residues
MPKLLLLHGPNLNRLGTREPERYGRLTLQDIETRLRSICDAAGVQLCSAQSNHEGELIDRIHAAADEGVEFIVINPAALT
HTSVGLRDALLAVALPFIEVHLSNVHAREAFRQHSYLSDIAEGVITGLGADGYDFAARAAIRRMGGQA
>Mature_147_residues
PKLLLLHGPNLNRLGTREPERYGRLTLQDIETRLRSICDAAGVQLCSAQSNHEGELIDRIHAAADEGVEFIVINPAALTH
TSVGLRDALLAVALPFIEVHLSNVHAREAFRQHSYLSDIAEGVITGLGADGYDFAARAAIRRMGGQA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_HALHL (A1WZI8)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003902.1
- ProteinModelPortal:   A1WZI8
- SMR:   A1WZI8
- STRING:   A1WZI8
- GeneID:   4709264
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2337
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- BioCyc:   HHAL349124:HHAL_2337-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16046; Mature: 15915

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLLLLHGPNLNRLGTREPERYGRLTLQDIETRLRSICDAAGVQLCSAQSNHEGELIDR
CCCEEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IHAAADEGVEFIVINPAALTHTSVGLRDALLAVALPFIEVHLSNVHAREAFRQHSYLSDI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEGVITGLGADGYDFAARAAIRRMGGQA
HHHHHHHCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PKLLLLHGPNLNRLGTREPERYGRLTLQDIETRLRSICDAAGVQLCSAQSNHEGELIDR
CCEEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IHAAADEGVEFIVINPAALTHTSVGLRDALLAVALPFIEVHLSNVHAREAFRQHSYLSDI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEGVITGLGADGYDFAARAAIRRMGGQA
HHHHHHHCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA