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The map label for this gene is pntAB [H]

Identifier: 121999054

GI number: 121999054

Start: 2497246

End: 2497545

Strand: Reverse

Name: pntAB [H]

Synonym: Hhal_2275

Alternate gene names: 121999054

Gene position: 2497545-2497246 (Counterclockwise)

Preceding gene: 121999055

Following gene: 121999053

Centisome position: 93.25

GC content: 64.33

Gene sequence:

>300_bases
ATGATCGAGGTCGGCGGGCTCGTCGCACTGTACGTCTTCATGCTCGCGGCGGTGGCTGGTTACGAGGTCATCACCCGGGT
GCCGGTCATCCTGCATACGCCGCTGATGTCCGGTTCGAACTTCATCCACGGTATCGTCGTCGTCGGTGCCATGGTCGCTC
TCGGTGTCGCTGAGACGCCGCTGGAGCAGGCCATCGGCTTTGTCGCCGTGCTGCTCGGCGCCGCCAACGCCGTCGGCGGC
TACGTCGTCACCGAGCGGATGCTCGACATGTTCAAGAGCAGCAAGAAGGAGGACGGCTGA

Upstream 100 bases:

>100_bases
CTCTGAACTGGGACGACCAGGTGATCGCGGATACCTGTCTGACCCACGACGGCCAGGTTCGCCACGGGGCCACCCGGGAG
CGCCTGGAAGGAGGTAAGTC

Downstream 100 bases:

>100_bases
ACATGAGTGTCGTAGTCCAACTCAGTTACTTCGTCGCCTCCGTCCTGTTCATCTTCGGCCTCAAGGCCATGAGCTCGCCG
GTGACGGCGCGCAAGGGCGT

Product: pyridine nucleotide transhydrogenase subunit alpha

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 99; Mature: 99

Protein sequence:

>99_residues
MIEVGGLVALYVFMLAAVAGYEVITRVPVILHTPLMSGSNFIHGIVVVGAMVALGVAETPLEQAIGFVAVLLGAANAVGG
YVVTERMLDMFKSSKKEDG

Sequences:

>Translated_99_residues
MIEVGGLVALYVFMLAAVAGYEVITRVPVILHTPLMSGSNFIHGIVVVGAMVALGVAETPLEQAIGFVAVLLGAANAVGG
YVVTERMLDMFKSSKKEDG
>Mature_99_residues
MIEVGGLVALYVFMLAAVAGYEVITRVPVILHTPLMSGSNFIHGIVVVGAMVALGVAETPLEQAIGFVAVLLGAANAVGG
YVVTERMLDMFKSSKKEDG

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787887, Length=83, Percent_Identity=46.9879518072289, Blast_Score=71, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17550456, Length=89, Percent_Identity=39.3258426966292, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 10293; Mature: 10293

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVGGLVALYVFMLAAVAGYEVITRVPVILHTPLMSGSNFIHGIVVVGAMVALGVAETP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC
LEQAIGFVAVLLGAANAVGGYVVTERMLDMFKSSKKEDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIEVGGLVALYVFMLAAVAGYEVITRVPVILHTPLMSGSNFIHGIVVVGAMVALGVAETP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC
LEQAIGFVAVLLGAANAVGGYVVTERMLDMFKSSKKEDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]