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The map label for this gene is murB

Identifier: 121998868

GI number: 121998868

Start: 2292849

End: 2293754

Strand: Reverse

Name: murB

Synonym: Hhal_2089

Alternate gene names: 121998868

Gene position: 2293754-2292849 (Counterclockwise)

Preceding gene: 121998869

Following gene: 121998867

Centisome position: 85.64

GC content: 73.18

Gene sequence:

>906_bases
ATGAGTGCAGCCGCGGAACGGCGCCGGATCCGGCCCGGCGAGTGGCGCGAGCAGGAGCCCATGGCCGGGTACACCACCTG
GCGGGTGGGTGGCCCGGCGCGGCGCCTGTTCTGCCCGGCCGACCGGGCCGGACTGCTCGACTGCCTGGCCCGGCTGTCGG
CCGAGGAGCCGCTGCACTGGTGCGGCCTAGGCAGCAATCTGCTGGTGCGCGACGGCGGTGTGGCCGGGACGGTCATTTTG
AGTCAGGGCGGGCTGGATGGGCTGGCGGTCGACGGCGCGCAGGGGCGGGTCCATGCCGAGGCCGGCGTGGCCGGCGGTCG
CCTGGCTCGGGCGGCAGTCCGCGAAGGGCTGGCCGGTCTGGAGTTCCTGGCCGGTATCCCCGGCACTGTGGGCGGTGCGC
TGGCCCTCAACGCCGGGGCCTGGGGCGGCGAGACCTGGAGCCGTGTGGTCGAGGTGGAGACCGTCGATCGCCACGGGTGC
GTCCGGCGGCGCACACCGGCGGATTTCCGGGTCGGCTACCGCAGGGTTGTGGGCCCGGCCGGTGAGTGGTTCCTGGCTGC
CACCTGGGCGCTGCCTTCCGGCGACCCGCAAGCACTCAACGAGCGGGTGCGGGCGCTGCTGCGGCGGCGTAATGCGGCGC
AGCCGGTGGGTCAGCCGACCTGCGGTTCGGTCTTTCGGAATCCGCCTGGGGACGCCGCCGGGCGGCTGATCGAACAGGCC
GGGTTGAAAGGGGCGCGGCGTGGTGGTGCCCGGGTCTCCGAGCGCCACGCCAACTTCATTATCAACGAGGGCGGCAGTGC
GGCGGATATCGAGGGGCTCATCGAGGTGGTCCGGCAGCGGGTTGCCGAGGTGCACGGTGTGCGGCTAGAGACCGAAGTCC
ACGTGATCGGGGGGGAGCAGTCGTGA

Upstream 100 bases:

>100_bases
GGCTGCTGCGTGACGACGACGTGGTGCTGACCCTGGGGGCCGGCAGTATTGGCGGGCTTCCGGCGCAGCTGGGCGGCGGT
CTGACCGCCGGGGGTGGGGC

Downstream 100 bases:

>100_bases
GTGGTATCCCGGATCCGCAGCGGGTGGGGCGCGTCGCCGTGCTGATGGGCGGCACCTCGGCCGAGCGGGACATCTCCCTG
CGCAGTGGCGGCGCGATACT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSAAAERRRIRPGEWREQEPMAGYTTWRVGGPARRLFCPADRAGLLDCLARLSAEEPLHWCGLGSNLLVRDGGVAGTVIL
SQGGLDGLAVDGAQGRVHAEAGVAGGRLARAAVREGLAGLEFLAGIPGTVGGALALNAGAWGGETWSRVVEVETVDRHGC
VRRRTPADFRVGYRRVVGPAGEWFLAATWALPSGDPQALNERVRALLRRRNAAQPVGQPTCGSVFRNPPGDAAGRLIEQA
GLKGARRGGARVSERHANFIINEGGSAADIEGLIEVVRQRVAEVHGVRLETEVHVIGGEQS

Sequences:

>Translated_301_residues
MSAAAERRRIRPGEWREQEPMAGYTTWRVGGPARRLFCPADRAGLLDCLARLSAEEPLHWCGLGSNLLVRDGGVAGTVIL
SQGGLDGLAVDGAQGRVHAEAGVAGGRLARAAVREGLAGLEFLAGIPGTVGGALALNAGAWGGETWSRVVEVETVDRHGC
VRRRTPADFRVGYRRVVGPAGEWFLAATWALPSGDPQALNERVRALLRRRNAAQPVGQPTCGSVFRNPPGDAAGRLIEQA
GLKGARRGGARVSERHANFIINEGGSAADIEGLIEVVRQRVAEVHGVRLETEVHVIGGEQS
>Mature_300_residues
SAAAERRRIRPGEWREQEPMAGYTTWRVGGPARRLFCPADRAGLLDCLARLSAEEPLHWCGLGSNLLVRDGGVAGTVILS
QGGLDGLAVDGAQGRVHAEAGVAGGRLARAAVREGLAGLEFLAGIPGTVGGALALNAGAWGGETWSRVVEVETVDRHGCV
RRRTPADFRVGYRRVVGPAGEWFLAATWALPSGDPQALNERVRALLRRRNAAQPVGQPTCGSVFRNPPGDAAGRLIEQAG
LKGARRGGARVSERHANFIINEGGSAADIEGLIEVVRQRVAEVHGVRLETEVHVIGGEQS

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 31812; Mature: 31681

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAAERRRIRPGEWREQEPMAGYTTWRVGGPARRLFCPADRAGLLDCLARLSAEEPLHW
CCCCHHHHCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCHHHHHHHHHHHCCCCCCEE
CGLGSNLLVRDGGVAGTVILSQGGLDGLAVDGAQGRVHAEAGVAGGRLARAAVREGLAGL
ECCCCCEEEECCCCEEEEEEECCCCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHH
EFLAGIPGTVGGALALNAGAWGGETWSRVVEVETVDRHGCVRRRTPADFRVGYRRVVGPA
HHHHCCCCCCCCCEEECCCCCCCHHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCC
GEWFLAATWALPSGDPQALNERVRALLRRRNAAQPVGQPTCGSVFRNPPGDAAGRLIEQA
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHH
GLKGARRGGARVSERHANFIINEGGSAADIEGLIEVVRQRVAEVHGVRLETEVHVIGGEQ
CCCHHHCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCC
S
C
>Mature Secondary Structure 
SAAAERRRIRPGEWREQEPMAGYTTWRVGGPARRLFCPADRAGLLDCLARLSAEEPLHW
CCCHHHHCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCHHHHHHHHHHHCCCCCCEE
CGLGSNLLVRDGGVAGTVILSQGGLDGLAVDGAQGRVHAEAGVAGGRLARAAVREGLAGL
ECCCCCEEEECCCCEEEEEEECCCCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHH
EFLAGIPGTVGGALALNAGAWGGETWSRVVEVETVDRHGCVRRRTPADFRVGYRRVVGPA
HHHHCCCCCCCCCEEECCCCCCCHHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCC
GEWFLAATWALPSGDPQALNERVRALLRRRNAAQPVGQPTCGSVFRNPPGDAAGRLIEQA
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHH
GLKGARRGGARVSERHANFIINEGGSAADIEGLIEVVRQRVAEVHGVRLETEVHVIGGEQ
CCCHHHCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA