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The map label for this gene is trpD

Identifier: 121998859

GI number: 121998859

Start: 2283726

End: 2284754

Strand: Reverse

Name: trpD

Synonym: Hhal_2080

Alternate gene names: 121998859

Gene position: 2284754-2283726 (Counterclockwise)

Preceding gene: 121998860

Following gene: 121998858

Centisome position: 85.3

GC content: 70.36

Gene sequence:

>1029_bases
ATGGACCTAACCGCCGCCCTTCGTCGCATCACGGAGAACCAGGATCTCAGCCCCGATGAGATGACCGCGGTCTTCCGCAC
CATCATGACCGGCGGGGCGACGCCGGCGCAGATCGGTGGCTTCCTCATCGGCATGCGGCTCAAGGGGGAGACGGTCCAGG
AGATGGCCGCCGCCGCCTCGGTCATGCGGGAGCTCGCCGAGCGGGTCGATGTCGGCGACGACTTCCACCGCCTGGTGGAC
ACCTGCGGCACCGGTGGCGATGCCCGCGGCACCCTGAACGTCTCGACCGCCGCCGCCTTCGTGACCGCCGCCGGGGGCAT
CCCGGTGGCCAAGCACGGCAACCGCTCGGTCTCCGGGCGCAGCGGCAGCGCCGACCTGCTCGAGGCCTGCGGCGCCACGC
TGGAACTCAGCAGCGAGGCGGTGGCTGAGTGCATCCGTCGGGTCAACGTTGGTTTCCTCTTCGCCCCGCTGCACCACAGC
GCCATGAAGCACGCCGTGGGACCGCGCAAGGAGCTCGGGGTCCGCACCCTGTTCAACCTGGTGGGCCCGTTGTCCAACCC
CGCCGGGGCGCGGCGCCAGCTGCTCGGGGTCTTCGGGCAGGAGTGGGTGCGCCCGGTGGCCGAGGTGCTCCAGGCGCTGG
GCAGCGACCACGTGCTGGTGGTCCACGCCGAGGACGGGCTCGACGAGATCAGCATCGCCGCACCGACGCGGATCGCCGAG
CTGCGCAACGGCCAGATCGAGGAGTACACCGTCACGCCGGAGGATCTGGGGCTGCGCAGCGCGCCGCTCAATGAGGTGAC
CATCTCCGGCACCAAGGACAGTCTGGCGATGATCCGTGCCGCCTTCTCCGGCGAGCGCATTGCCGCCATGGAGCTGATCG
CCGCCAACGCCGGCGCTGCGCTCTATGTTGGCGGCGAGGCCCCCGATCTGCGTCGTGGTGTGGAGCGAGCCCGGGAACTC
ATGACCTCCGGTGCCGCCGCTCAGACGCTGGAGCGCTTCGTGGCGACGACCAAGGAACTCGCCCAATGA

Upstream 100 bases:

>100_bases
GCACGATCTTCTGCGCAACTTCCTGGAGCAGCCCCGCGCCGTCGCCTGAACCCTGCGCCCTGAACGCTGCACACTGAACC
GAAAAAAACCGAGGCACCCT

Downstream 100 bases:

>100_bases
GCGCGCCCGGGACGCCGGATATCCTGCGCCGCATCCTGCGCCGTAAGGTCGAGGAGGTGGTCGAGCGGGCCGAGAGCCGC
TCGCTGCGCGAGCTCTCGGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MDLTAALRRITENQDLSPDEMTAVFRTIMTGGATPAQIGGFLIGMRLKGETVQEMAAAASVMRELAERVDVGDDFHRLVD
TCGTGGDARGTLNVSTAAAFVTAAGGIPVAKHGNRSVSGRSGSADLLEACGATLELSSEAVAECIRRVNVGFLFAPLHHS
AMKHAVGPRKELGVRTLFNLVGPLSNPAGARRQLLGVFGQEWVRPVAEVLQALGSDHVLVVHAEDGLDEISIAAPTRIAE
LRNGQIEEYTVTPEDLGLRSAPLNEVTISGTKDSLAMIRAAFSGERIAAMELIAANAGAALYVGGEAPDLRRGVERAREL
MTSGAAAQTLERFVATTKELAQ

Sequences:

>Translated_342_residues
MDLTAALRRITENQDLSPDEMTAVFRTIMTGGATPAQIGGFLIGMRLKGETVQEMAAAASVMRELAERVDVGDDFHRLVD
TCGTGGDARGTLNVSTAAAFVTAAGGIPVAKHGNRSVSGRSGSADLLEACGATLELSSEAVAECIRRVNVGFLFAPLHHS
AMKHAVGPRKELGVRTLFNLVGPLSNPAGARRQLLGVFGQEWVRPVAEVLQALGSDHVLVVHAEDGLDEISIAAPTRIAE
LRNGQIEEYTVTPEDLGLRSAPLNEVTISGTKDSLAMIRAAFSGERIAAMELIAANAGAALYVGGEAPDLRRGVERAREL
MTSGAAAQTLERFVATTKELAQ
>Mature_342_residues
MDLTAALRRITENQDLSPDEMTAVFRTIMTGGATPAQIGGFLIGMRLKGETVQEMAAAASVMRELAERVDVGDDFHRLVD
TCGTGGDARGTLNVSTAAAFVTAAGGIPVAKHGNRSVSGRSGSADLLEACGATLELSSEAVAECIRRVNVGFLFAPLHHS
AMKHAVGPRKELGVRTLFNLVGPLSNPAGARRQLLGVFGQEWVRPVAEVLQALGSDHVLVVHAEDGLDEISIAAPTRIAE
LRNGQIEEYTVTPEDLGLRSAPLNEVTISGTKDSLAMIRAAFSGERIAAMELIAANAGAALYVGGEAPDLRRGVERAREL
MTSGAAAQTLERFVATTKELAQ

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=268, Percent_Identity=41.7910447761194, Blast_Score=196, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6320561, Length=368, Percent_Identity=25.8152173913043, Blast_Score=117, Evalue=4e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_HALHL (A1WYT2)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003646.1
- ProteinModelPortal:   A1WYT2
- SMR:   A1WYT2
- STRING:   A1WYT2
- GeneID:   4709990
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2080
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- PhylomeDB:   A1WYT2
- BioCyc:   HHAL349124:HHAL_2080-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35963; Mature: 35963

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTAALRRITENQDLSPDEMTAVFRTIMTGGATPAQIGGFLIGMRLKGETVQEMAAAAS
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCHHHHHHHHHHH
VMRELAERVDVGDDFHRLVDTCGTGGDARGTLNVSTAAAFVTAAGGIPVAKHGNRSVSGR
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCC
SGSADLLEACGATLELSSEAVAECIRRVNVGFLFAPLHHSAMKHAVGPRKELGVRTLFNL
CCCHHHHHHCCCCEECCHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHH
VGPLSNPAGARRQLLGVFGQEWVRPVAEVLQALGSDHVLVVHAEDGLDEISIAAPTRIAE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEECCCCHHHHH
LRNGQIEEYTVTPEDLGLRSAPLNEVTISGTKDSLAMIRAAFSGERIAAMELIAANAGAA
HCCCCCEEEEECHHHCCCCCCCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCE
LYVGGEAPDLRRGVERARELMTSGAAAQTLERFVATTKELAQ
EEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLTAALRRITENQDLSPDEMTAVFRTIMTGGATPAQIGGFLIGMRLKGETVQEMAAAAS
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCHHHHHHHHHHH
VMRELAERVDVGDDFHRLVDTCGTGGDARGTLNVSTAAAFVTAAGGIPVAKHGNRSVSGR
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCC
SGSADLLEACGATLELSSEAVAECIRRVNVGFLFAPLHHSAMKHAVGPRKELGVRTLFNL
CCCHHHHHHCCCCEECCHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHH
VGPLSNPAGARRQLLGVFGQEWVRPVAEVLQALGSDHVLVVHAEDGLDEISIAAPTRIAE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEECCCCHHHHH
LRNGQIEEYTVTPEDLGLRSAPLNEVTISGTKDSLAMIRAAFSGERIAAMELIAANAGAA
HCCCCCEEEEECHHHCCCCCCCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCE
LYVGGEAPDLRRGVERARELMTSGAAAQTLERFVATTKELAQ
EEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA