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The map label for this gene is speD [H]

Identifier: 121998857

GI number: 121998857

Start: 2281937

End: 2282815

Strand: Reverse

Name: speD [H]

Synonym: Hhal_2078

Alternate gene names: 121998857

Gene position: 2282815-2281937 (Counterclockwise)

Preceding gene: 121998858

Following gene: 121998856

Centisome position: 85.23

GC content: 61.21

Gene sequence:

>879_bases
GTGCATAATTCCCGCTCTCTTGAGCGCACACTTCCCAACAACGACGGGAGGGCCCAGGCGTTGGTCGATTACACCCGCAT
CCGGCTCCACGGCTTCAACAATCTGACCAAGTCGTTGAGCTTCAATATCTACGACGTTTGCTACGCCAAGACCGAGGCGC
AGCGGCGGGCGTACATCGAATACATCGACGAAGAGTACAACGCCGAGCGGCTAACCGAGATCCTTACCAATGTCGCCGAG
ATCATCGGCGCCAATGTGCTCAACGTGGCGCGTCAGGACTACGACCCGCAGGGCGCCAGCGTGACCATCCTCATCTCCGA
GGGGCCGGTCTCCCCCGAGGAGGCCGAGGAGAGCGCCGAGGCGCGGCCGGGGCCGCTGCCCGACGACGTGGTGGCCCACC
TGGACAAGTCGCACATCACCGTGCACACGTACCCGGAGATGCACCCGGACAAGGGAGTGAGCACCTTTCGGGCGGACATC
GACGTCTCCACCTGCGGGGTCATCTCACCACTGACGGCGCTCAACTACCTGATTCACTCCTTTGACTCGGACATCGTGAC
CATGGACTACCGCGTGCGCGGCTTCACCCGCGACGTGGAGGGCCACAAGCACTTCATCGATCACGAGATCAACTCGATCC
AGAACTACCTGTCCGAGGATACAAAGGAGCGCTACCAGACCCTGGACGTGAACGTCTACCAGGAGAACATCTTCCACACG
AAGATGATCCTGCGCGAGTTCGATCTGGATAACTACCTCTTCGGGGAGTCGAGCGCGGACCTCGACGAGGAGGAGGCGAA
CACCATCCGCAGGCACCTGCGCCGGGAGATGATGGAGATCTTCGCCGGGCGTAACCTGCCGGCCAACCAAGAAGTCTGA

Upstream 100 bases:

>100_bases
TGTAACCGGCCCCCCTGGGCGAGCGGGTTCCCGGGGGCCGTGGCGGAACGGTGGCAGTCATGACGCTGTCCACCACAAAG
GTGGCGTTATCGCCAGATTT

Downstream 100 bases:

>100_bases
GCCGCCGCGGACGGCGGGGGCGGCGGCGGTTGCCAGTACCGCTGCCTTCCGTTATGATGCGCGGTCTTCGACGGAGAGAG
CGAAGCGATGAAGACGTATA

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MHNSRSLERTLPNNDGRAQALVDYTRIRLHGFNNLTKSLSFNIYDVCYAKTEAQRRAYIEYIDEEYNAERLTEILTNVAE
IIGANVLNVARQDYDPQGASVTILISEGPVSPEEAEESAEARPGPLPDDVVAHLDKSHITVHTYPEMHPDKGVSTFRADI
DVSTCGVISPLTALNYLIHSFDSDIVTMDYRVRGFTRDVEGHKHFIDHEINSIQNYLSEDTKERYQTLDVNVYQENIFHT
KMILREFDLDNYLFGESSADLDEEEANTIRRHLRREMMEIFAGRNLPANQEV

Sequences:

>Translated_292_residues
MHNSRSLERTLPNNDGRAQALVDYTRIRLHGFNNLTKSLSFNIYDVCYAKTEAQRRAYIEYIDEEYNAERLTEILTNVAE
IIGANVLNVARQDYDPQGASVTILISEGPVSPEEAEESAEARPGPLPDDVVAHLDKSHITVHTYPEMHPDKGVSTFRADI
DVSTCGVISPLTALNYLIHSFDSDIVTMDYRVRGFTRDVEGHKHFIDHEINSIQNYLSEDTKERYQTLDVNVYQENIFHT
KMILREFDLDNYLFGESSADLDEEEANTIRRHLRREMMEIFAGRNLPANQEV
>Mature_292_residues
MHNSRSLERTLPNNDGRAQALVDYTRIRLHGFNNLTKSLSFNIYDVCYAKTEAQRRAYIEYIDEEYNAERLTEILTNVAE
IIGANVLNVARQDYDPQGASVTILISEGPVSPEEAEESAEARPGPLPDDVVAHLDKSHITVHTYPEMHPDKGVSTFRADI
DVSTCGVISPLTALNYLIHSFDSDIVTMDYRVRGFTRDVEGHKHFIDHEINSIQNYLSEDTKERYQTLDVNVYQENIFHT
KMILREFDLDNYLFGESSADLDEEEANTIRRHLRREMMEIFAGRNLPANQEV

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786311, Length=263, Percent_Identity=67.680608365019, Blast_Score=379, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR009165
- InterPro:   IPR016067 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 33471; Mature: 33471

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNSRSLERTLPNNDGRAQALVDYTRIRLHGFNNLTKSLSFNIYDVCYAKTEAQRRAYIE
CCCCCCHHHHCCCCCCCHHHHHHHHHHEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHH
YIDEEYNAERLTEILTNVAEIIGANVLNVARQDYDPQGASVTILISEGPVSPEEAEESAE
HHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHC
ARPGPLPDDVVAHLDKSHITVHTYPEMHPDKGVSTFRADIDVSTCGVISPLTALNYLIHS
CCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHH
FDSDIVTMDYRVRGFTRDVEGHKHFIDHEINSIQNYLSEDTKERYQTLDVNVYQENIFHT
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
KMILREFDLDNYLFGESSADLDEEEANTIRRHLRREMMEIFAGRNLPANQEV
HHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHNSRSLERTLPNNDGRAQALVDYTRIRLHGFNNLTKSLSFNIYDVCYAKTEAQRRAYIE
CCCCCCHHHHCCCCCCCHHHHHHHHHHEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHH
YIDEEYNAERLTEILTNVAEIIGANVLNVARQDYDPQGASVTILISEGPVSPEEAEESAE
HHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHC
ARPGPLPDDVVAHLDKSHITVHTYPEMHPDKGVSTFRADIDVSTCGVISPLTALNYLIHS
CCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHH
FDSDIVTMDYRVRGFTRDVEGHKHFIDHEINSIQNYLSEDTKERYQTLDVNVYQENIFHT
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
KMILREFDLDNYLFGESSADLDEEEANTIRRHLRREMMEIFAGRNLPANQEV
HHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA