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The map label for this gene is phbC [H]

Identifier: 121998841

GI number: 121998841

Start: 2264476

End: 2266233

Strand: Reverse

Name: phbC [H]

Synonym: Hhal_2062

Alternate gene names: 121998841

Gene position: 2266233-2264476 (Counterclockwise)

Preceding gene: 121998842

Following gene: 121998840

Centisome position: 84.61

GC content: 65.93

Gene sequence:

>1758_bases
ATGGTCCATTCCCTGATGCCCGAATTCGAAGAGAGTGAGCGCGAGGCGCTGACCGCAGATCGGCTGTTCAACGCCGGCTT
GGGCCGTTATACGCAAGGGCTTTCGCCGGCGGCGGTGTCGCTGGCGACTTTTGATTGGGCCGTTCACCTGGCGACCCACC
CGGGCAAGCAGTTCGCGCTCATGGACGAGGCCATGCGCAACGCCATGCGCTACAATGCCTACGTCTTCAGCCGCATGACC
GGCACCTGCCCGGAGCCGTGCGCCAAGCCCTGGCCGGGCGACGACCGCTTCTCCGCCGAGCAGTGGCAGCGCTTCCCCTA
CGACGTCCTGGAGCAGGGCTTCCTGCTCACCCAGCAGTGGTGGCACAGCGCCACCACCGGGAACCGCGGGGTGACTCAGC
ACCACGAGGATGTGGTCAACTTCCTCGGTCGCCAGGTGCTCGATTTCTACTCCCCCTCCAACTTCCTGGCCACCAACCCC
GAGGTGCTCGAGGAGACCCTCAGCCAGGGCGGTGCCAATCTGGTGCAGGGGTTTGCCAATCTGCTTGAGGACACCGAGCG
CACCATCAGTGACCGTCCACCGGTGGGCGCAGAAGATTGGAAGGTGGGCGAGAACCTGGCGGTGACGCCGGGCAAGGTGG
TCTACCGCAACCGGATCATGGAGCTGATCCAGTACCAGCCCACCACCAAGACCGTCTACCCCGAGCCGATCCTCATCTGC
CCGGCGTGGATCATGAAGTACTACATCCTCGACCTGCGCCCCGGCAAATCCCTGATCGAGTACCTGGTCAGCAAGGGCCA
TACGGTCTTCGTCATCTCCTGGAAGAACCCGGGCAGCGAGGACCGCGATCTGGGCATGGATACCTACCGCCGGGAAGGCG
TCATGGACGCCCTGGAGGCGGTGACCACCATCGTCCCCGAACGCAAGGTCCACACCGTCGGCTACTGCTTGGGGGGCACC
CTGCTGATGCTCGCCGCGGCGACCATGGCGCGAGATGGCGATGACCGCCTCGCCAGCCTCAGCCTGCTGGCGGCCCAGGC
GGACTTTACCGAGCCCGGCGAGCTGGAGCTGTTCATCGACGAGAGCCAGGTCACCTTCCTCGAGGACATGATGTGGGAGA
AGGGCTACCTGGACGGCGCCAAGATGGCTGGGGCCTTCCAGCTGCTGCGCTCCAAGGACCTGATCTACTCGCGGCTGATC
CACGACTACCTGATGGGCAAGCGGGCCCCGGTGATCGACCTGATGGCGTGGAACGCCGATACCACCCGGCTGCCCTTCCG
CATGCATAGCGAGTACCTGCGCGATCTGTTCCTCAACAACGACTTCGTCGAGGATCGTTACGACGTGGGTGGCCAGCCCA
TCCACATCGGCGATATCCAGGTGCCGACCTTCGCCGTGGGGACCGAGAAGGACCACATCGCGCCGTGGCGTTCGGTCTAC
AAGATCAACCGCTTCCTGCCCCGGGCCGATGTCACCTTCGCGCTGACCCAGGGCGGCCACAACGCCGGCATCGTCACGCC
CCCGGGGCACCCACGCCGCATCTACCGCAGCCTCGCGCGCCGCTACGGGGATCCCTACGTGCCGTCCCACGTCTTCCTGG
AGAAGGCCACTGAGCAGCAGGGCTCCTGGTGGCCGGAGTGGGAGCAGTGGCTGCGCGAGCGCTCGGGGAGCCGGGTGGCA
CCGCCGAGCCTGGGCCAGAGCGAGGGGACGTACCAGCCCCTGACCGAAGCCCCCGGCACCTACGTGCTGCAGTCGTGA

Upstream 100 bases:

>100_bases
CCGACTTGACACCACCCGCCCCCAGGGCCGAGATTGTGCACTGCGGCACGGTGGCTGGAAGCGCCGTGCGCGGCCCATTC
TGCAATGCCGAGGAACCGCC

Downstream 100 bases:

>100_bases
GCCAGAGCAGGTCGATGACCGTACGCAACTTCCTCTTCGACGAGCTCCACGTGGGCCAGCAGGTGGAGACCACCAGTCGG
CTCAACCACCAGGACGTGCG

Product: poly-beta-hydroxybutyrate polymerase domain-containing protein

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MVHSLMPEFEESEREALTADRLFNAGLGRYTQGLSPAAVSLATFDWAVHLATHPGKQFALMDEAMRNAMRYNAYVFSRMT
GTCPEPCAKPWPGDDRFSAEQWQRFPYDVLEQGFLLTQQWWHSATTGNRGVTQHHEDVVNFLGRQVLDFYSPSNFLATNP
EVLEETLSQGGANLVQGFANLLEDTERTISDRPPVGAEDWKVGENLAVTPGKVVYRNRIMELIQYQPTTKTVYPEPILIC
PAWIMKYYILDLRPGKSLIEYLVSKGHTVFVISWKNPGSEDRDLGMDTYRREGVMDALEAVTTIVPERKVHTVGYCLGGT
LLMLAAATMARDGDDRLASLSLLAAQADFTEPGELELFIDESQVTFLEDMMWEKGYLDGAKMAGAFQLLRSKDLIYSRLI
HDYLMGKRAPVIDLMAWNADTTRLPFRMHSEYLRDLFLNNDFVEDRYDVGGQPIHIGDIQVPTFAVGTEKDHIAPWRSVY
KINRFLPRADVTFALTQGGHNAGIVTPPGHPRRIYRSLARRYGDPYVPSHVFLEKATEQQGSWWPEWEQWLRERSGSRVA
PPSLGQSEGTYQPLTEAPGTYVLQS

Sequences:

>Translated_585_residues
MVHSLMPEFEESEREALTADRLFNAGLGRYTQGLSPAAVSLATFDWAVHLATHPGKQFALMDEAMRNAMRYNAYVFSRMT
GTCPEPCAKPWPGDDRFSAEQWQRFPYDVLEQGFLLTQQWWHSATTGNRGVTQHHEDVVNFLGRQVLDFYSPSNFLATNP
EVLEETLSQGGANLVQGFANLLEDTERTISDRPPVGAEDWKVGENLAVTPGKVVYRNRIMELIQYQPTTKTVYPEPILIC
PAWIMKYYILDLRPGKSLIEYLVSKGHTVFVISWKNPGSEDRDLGMDTYRREGVMDALEAVTTIVPERKVHTVGYCLGGT
LLMLAAATMARDGDDRLASLSLLAAQADFTEPGELELFIDESQVTFLEDMMWEKGYLDGAKMAGAFQLLRSKDLIYSRLI
HDYLMGKRAPVIDLMAWNADTTRLPFRMHSEYLRDLFLNNDFVEDRYDVGGQPIHIGDIQVPTFAVGTEKDHIAPWRSVY
KINRFLPRADVTFALTQGGHNAGIVTPPGHPRRIYRSLARRYGDPYVPSHVFLEKATEQQGSWWPEWEQWLRERSGSRVA
PPSLGQSEGTYQPLTEAPGTYVLQS
>Mature_585_residues
MVHSLMPEFEESEREALTADRLFNAGLGRYTQGLSPAAVSLATFDWAVHLATHPGKQFALMDEAMRNAMRYNAYVFSRMT
GTCPEPCAKPWPGDDRFSAEQWQRFPYDVLEQGFLLTQQWWHSATTGNRGVTQHHEDVVNFLGRQVLDFYSPSNFLATNP
EVLEETLSQGGANLVQGFANLLEDTERTISDRPPVGAEDWKVGENLAVTPGKVVYRNRIMELIQYQPTTKTVYPEPILIC
PAWIMKYYILDLRPGKSLIEYLVSKGHTVFVISWKNPGSEDRDLGMDTYRREGVMDALEAVTTIVPERKVHTVGYCLGGT
LLMLAAATMARDGDDRLASLSLLAAQADFTEPGELELFIDESQVTFLEDMMWEKGYLDGAKMAGAFQLLRSKDLIYSRLI
HDYLMGKRAPVIDLMAWNADTTRLPFRMHSEYLRDLFLNNDFVEDRYDVGGQPIHIGDIQVPTFAVGTEKDHIAPWRSVY
KINRFLPRADVTFALTQGGHNAGIVTPPGHPRRIYRSLARRYGDPYVPSHVFLEKATEQQGSWWPEWEQWLRERSGSRVA
PPSLGQSEGTYQPLTEAPGTYVLQS

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 66232; Mature: 66232

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHSLMPEFEESEREALTADRLFNAGLGRYTQGLSPAAVSLATFDWAVHLATHPGKQFAL
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHEEEEEECCCCCHHHH
MDEAMRNAMRYNAYVFSRMTGTCPEPCAKPWPGDDRFSAEQWQRFPYDVLEQGFLLTQQW
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCHHHHH
WHSATTGNRGVTQHHEDVVNFLGRQVLDFYSPSNFLATNPEVLEETLSQGGANLVQGFAN
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
LLEDTERTISDRPPVGAEDWKVGENLAVTPGKVVYRNRIMELIQYQPTTKTVYPEPILIC
HHHHHHHHHCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEC
PAWIMKYYILDLRPGKSLIEYLVSKGHTVFVISWKNPGSEDRDLGMDTYRREGVMDALEA
HHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
VTTIVPERKVHTVGYCLGGTLLMLAAATMARDGDDRLASLSLLAAQADFTEPGELELFID
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEC
ESQVTFLEDMMWEKGYLDGAKMAGAFQLLRSKDLIYSRLIHDYLMGKRAPVIDLMAWNAD
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
TTRLPFRMHSEYLRDLFLNNDFVEDRYDVGGQPIHIGDIQVPTFAVGTEKDHIAPWRSVY
CCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHH
KINRFLPRADVTFALTQGGHNAGIVTPPGHPRRIYRSLARRYGDPYVPSHVFLEKATEQQ
HHHHHCCCCCEEEEEECCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GSWWPEWEQWLRERSGSRVAPPSLGQSEGTYQPLTEAPGTYVLQS
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCEEECC
>Mature Secondary Structure
MVHSLMPEFEESEREALTADRLFNAGLGRYTQGLSPAAVSLATFDWAVHLATHPGKQFAL
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHEEEEEECCCCCHHHH
MDEAMRNAMRYNAYVFSRMTGTCPEPCAKPWPGDDRFSAEQWQRFPYDVLEQGFLLTQQW
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCHHHHH
WHSATTGNRGVTQHHEDVVNFLGRQVLDFYSPSNFLATNPEVLEETLSQGGANLVQGFAN
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
LLEDTERTISDRPPVGAEDWKVGENLAVTPGKVVYRNRIMELIQYQPTTKTVYPEPILIC
HHHHHHHHHCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEC
PAWIMKYYILDLRPGKSLIEYLVSKGHTVFVISWKNPGSEDRDLGMDTYRREGVMDALEA
HHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
VTTIVPERKVHTVGYCLGGTLLMLAAATMARDGDDRLASLSLLAAQADFTEPGELELFID
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEC
ESQVTFLEDMMWEKGYLDGAKMAGAFQLLRSKDLIYSRLIHDYLMGKRAPVIDLMAWNAD
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
TTRLPFRMHSEYLRDLFLNNDFVEDRYDVGGQPIHIGDIQVPTFAVGTEKDHIAPWRSVY
CCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHH
KINRFLPRADVTFALTQGGHNAGIVTPPGHPRRIYRSLARRYGDPYVPSHVFLEKATEQQ
HHHHHCCCCCEEEEEECCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GSWWPEWEQWLRERSGSRVAPPSLGQSEGTYQPLTEAPGTYVLQS
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748438 [H]