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The map label for this gene is nrfC [H]

Identifier: 121998714

GI number: 121998714

Start: 2133015

End: 2133728

Strand: Reverse

Name: nrfC [H]

Synonym: Hhal_1935

Alternate gene names: 121998714

Gene position: 2133728-2133015 (Counterclockwise)

Preceding gene: 121998715

Following gene: 121998713

Centisome position: 79.66

GC content: 68.63

Gene sequence:

>714_bases
ATGAGACTGGGACTGGTCATCGATCTCGATACCTGCGTCGGGTGCCACGCCTGCGTCGTGGCGTGCAAGCAGTGGAACAC
CTCGGGGACGGTGGGCCCGCTCACCGACTACCACCCCTACGGCGAGGCTCCCAGTGGGGTGATGCTCAACCGCGTGCGCC
ACTACGAGGAGGGCACCTATCCGAACAGCAAGACCGTCAACGTGCCGGTCTCCTGCATGCACTGCGATGACCCGCCGTGC
GTCGATGTCTGTCCCACCGGGGCGTCTTACAAGCGGGACGCCGACGGGATCGTGCTGGTCGATGAGACCAAGTGCATGGG
CTGCAACTACTGCGCCTGGGCCTGCCCCTACGGCTGCCGGGAGCTCGACGGCGCCAGCGGCACGATGAAGAAGTGCACGC
TGTGCATCGACCGGATCTACGACGATCGCCTCCCGGAAGACGAGCGCCAGCCCGCCTGCGTGCTCTCCTGTCCAGCCCGG
GCGCGGCACTTCGGCGACCTTGACGACCCGGATTCTCGGGTCAGCCAGCTGGTGCGGGAGCGCCGTGGCTTCGTGATGCT
CCCGGAGATGGGGTGTCAGCCGGTCAACCACTACCTGCCGTTGCGGCCGCCCCAGGCCAGCCGCCCGCTGCCCGAGGCGG
CCGACCCGCCGCGGCAGGCGGCGGCCGACCCGGCAACGGTGCAGCACTGGACCAATCGCGTCGTTCACCGCTGA

Upstream 100 bases:

>100_bases
CGGGGGTCGATAACGGACCGCTGAAGTTCCTGCGGTACGCAACCCACCATGCGGTGCGCCTGCACCGCTCCATGCGCGAC
ATTCTAAGCCGGGGGCGTTG

Downstream 100 bases:

>100_bases
GGGAGGATCCACCCATGCATCCGGCCTGGTCCGTCGTCTTCTTCACGGTGCTCTCGGGCACCGGCTACGGGTTCATGGCG
CTGTTCGCCCTGACCGATGT

Product: 4Fe-4S ferredoxin iron-sulfur-binding domain-containing protein

Products: oxidized cytochrome C552; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MRLGLVIDLDTCVGCHACVVACKQWNTSGTVGPLTDYHPYGEAPSGVMLNRVRHYEEGTYPNSKTVNVPVSCMHCDDPPC
VDVCPTGASYKRDADGIVLVDETKCMGCNYCAWACPYGCRELDGASGTMKKCTLCIDRIYDDRLPEDERQPACVLSCPAR
ARHFGDLDDPDSRVSQLVRERRGFVMLPEMGCQPVNHYLPLRPPQASRPLPEAADPPRQAAADPATVQHWTNRVVHR

Sequences:

>Translated_237_residues
MRLGLVIDLDTCVGCHACVVACKQWNTSGTVGPLTDYHPYGEAPSGVMLNRVRHYEEGTYPNSKTVNVPVSCMHCDDPPC
VDVCPTGASYKRDADGIVLVDETKCMGCNYCAWACPYGCRELDGASGTMKKCTLCIDRIYDDRLPEDERQPACVLSCPAR
ARHFGDLDDPDSRVSQLVRERRGFVMLPEMGCQPVNHYLPLRPPQASRPLPEAADPPRQAAADPATVQHWTNRVVHR
>Mature_237_residues
MRLGLVIDLDTCVGCHACVVACKQWNTSGTVGPLTDYHPYGEAPSGVMLNRVRHYEEGTYPNSKTVNVPVSCMHCDDPPC
VDVCPTGASYKRDADGIVLVDETKCMGCNYCAWACPYGCRELDGASGTMKKCTLCIDRIYDDRLPEDERQPACVLSCPAR
ARHFGDLDDPDSRVSQLVRERRGFVMLPEMGCQPVNHYLPLRPPQASRPLPEAADPPRQAAADPATVQHWTNRVVHR

Specific function: Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI2367345, Length=209, Percent_Identity=36.8421052631579, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787872, Length=214, Percent_Identity=35.0467289719626, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787122, Length=220, Percent_Identity=33.1818181818182, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787749, Length=184, Percent_Identity=33.695652173913, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790326, Length=178, Percent_Identity=33.7078651685393, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI226510944, Length=173, Percent_Identity=34.6820809248555, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787740, Length=125, Percent_Identity=36, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789370, Length=182, Percent_Identity=35.1648351648352, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787478, Length=108, Percent_Identity=38.8888888888889, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082180, Length=185, Percent_Identity=30.2702702702703, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788811, Length=190, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367245, Length=170, Percent_Identity=28.8235294117647, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082179, Length=168, Percent_Identity=27.9761904761905, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789079, Length=206, Percent_Identity=28.1553398058252, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789067, Length=201, Percent_Identity=30.3482587064677, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI87082114, Length=208, Percent_Identity=27.8846153846154, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787963, Length=136, Percent_Identity=27.9411764705882, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017567
- InterPro:   IPR006311 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26191; Mature: 26191

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
10.5 %Cys+Met (Translated Protein)
7.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
10.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGLVIDLDTCVGCHACVVACKQWNTSGTVGPLTDYHPYGEAPSGVMLNRVRHYEEGTY
CCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
PNSKTVNVPVSCMHCDDPPCVDVCPTGASYKRDADGIVLVDETKCMGCNYCAWACPYGCR
CCCCEEECCEEEEECCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCH
ELDGASGTMKKCTLCIDRIYDDRLPEDERQPACVLSCPARARHFGDLDDPDSRVSQLVRE
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHH
RRGFVMLPEMGCQPVNHYLPLRPPQASRPLPEAADPPRQAAADPATVQHWTNRVVHR
HCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRLGLVIDLDTCVGCHACVVACKQWNTSGTVGPLTDYHPYGEAPSGVMLNRVRHYEEGTY
CCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
PNSKTVNVPVSCMHCDDPPCVDVCPTGASYKRDADGIVLVDETKCMGCNYCAWACPYGCR
CCCCEEECCEEEEECCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCH
ELDGASGTMKKCTLCIDRIYDDRLPEDERQPACVLSCPARARHFGDLDDPDSRVSQLVRE
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHH
RRGFVMLPEMGCQPVNHYLPLRPPQASRPLPEAADPPRQAAADPATVQHWTNRVVHR
HCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced cytochrome C552; nitrite [C]

Specific reaction: reduced cytochrome C552 + nitrite = oxidized cytochrome C552 + NH3 [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]