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The map label for this gene is idi

Identifier: 121998402

GI number: 121998402

Start: 1771114

End: 1771641

Strand: Reverse

Name: idi

Synonym: Hhal_1623

Alternate gene names: 121998402

Gene position: 1771641-1771114 (Counterclockwise)

Preceding gene: 121998406

Following gene: 121998401

Centisome position: 66.14

GC content: 66.1

Gene sequence:

>528_bases
ATGGAACACGTGGTGATCGTCGACCCGGAGGGGCAGCGCGTCGGCACCGAGGAGAAGATTCGCGCCCACGCCGACGGCGG
GACCCTGCACCTGGCGTTCTGCGTGTTCGTCTTCAATCCCCGAGGGGAGCTGCTCCTGCAGCGCCGTGCCGATAGTAAGT
ACCACTTCTCGGGCCTCTGGTCGAACACCTGCTGTGGCCACCCGCGGCCCGGCGAGGGCGTGACCGAGGCGGCCGAGCGC
CGATTAGGCGAGGAGTTCGGATTCGTCACTCGCCTGCACCCGGTTGCGCAGTTTACCTACCACGCGGAGGATCATCACAC
CGGGCTTGCCGAGTATGAATACGCCCATGTGCTGATTGGCCGCGCCCCGACGGATCAGCCGGCCCCCGATCCGCTTGAGA
TCGGTGCCTGGGAGTGGGCTGCCCCGTTGCGGATCCAGGCCGACACGCAGCAGTATCCCCTGCGGTATACGCCGTGGTTC
CGGCGCCTGATTCAAGAACAACCGGTTGCTGACTGGGCGACGGGTTAG

Upstream 100 bases:

>100_bases
TTGCCAGCGTTTAGAGAATGGTCGTACTATCGCGCCAGGCGCAAGGGGGGCGCGACGATGTTGCCCAATGTGCGCCCGAC
GTCTCAGCGGGGAGGACACG

Downstream 100 bases:

>100_bases
GGCTGTACCGACCGGGTCGCTCTGTTAATCTGCGCGCGGGCCGGGCGGCCCGCTTCCGCAAGGTCACTGATTTTCAAAAC
TGGGACGGCACAATCCATGG

Product: isopentenyl-diphosphate delta-isomerase, type 1

Products: NA

Alternate protein names: IPP isomerase; IPP:DMAPP isomerase; Isopentenyl pyrophosphate isomerase

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MEHVVIVDPEGQRVGTEEKIRAHADGGTLHLAFCVFVFNPRGELLLQRRADSKYHFSGLWSNTCCGHPRPGEGVTEAAER
RLGEEFGFVTRLHPVAQFTYHAEDHHTGLAEYEYAHVLIGRAPTDQPAPDPLEIGAWEWAAPLRIQADTQQYPLRYTPWF
RRLIQEQPVADWATG

Sequences:

>Translated_175_residues
MEHVVIVDPEGQRVGTEEKIRAHADGGTLHLAFCVFVFNPRGELLLQRRADSKYHFSGLWSNTCCGHPRPGEGVTEAAER
RLGEEFGFVTRLHPVAQFTYHAEDHHTGLAEYEYAHVLIGRAPTDQPAPDPLEIGAWEWAAPLRIQADTQQYPLRYTPWF
RRLIQEQPVADWATG
>Mature_175_residues
MEHVVIVDPEGQRVGTEEKIRAHADGGTLHLAFCVFVFNPRGELLLQRRADSKYHFSGLWSNTCCGHPRPGEGVTEAAER
RLGEEFGFVTRLHPVAQFTYHAEDHHTGLAEYEYAHVLIGRAPTDQPAPDPLEIGAWEWAAPLRIQADTQQYPLRYTPWF
RRLIQEQPVADWATG

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)

COG id: COG1443

COG function: function code I; Isopentenyldiphosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI40018633, Length=181, Percent_Identity=31.4917127071823, Blast_Score=90, Evalue=9e-19,
Organism=Homo sapiens, GI15147242, Length=183, Percent_Identity=26.775956284153, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789255, Length=163, Percent_Identity=34.3558282208589, Blast_Score=91, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17554092, Length=190, Percent_Identity=28.4210526315789, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6325140, Length=205, Percent_Identity=27.8048780487805, Blast_Score=82, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281362205, Length=184, Percent_Identity=27.7173913043478, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648688, Length=184, Percent_Identity=27.7173913043478, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDI_HALHL (A1WXH5)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003189.1
- ProteinModelPortal:   A1WXH5
- SMR:   A1WXH5
- STRING:   A1WXH5
- GeneID:   4709674
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1623
- eggNOG:   COG1443
- HOGENOM:   HBG416977
- OMA:   HKAVSVF
- PhylomeDB:   A1WXH5
- ProtClustDB:   CLSK2785190
- BioCyc:   HHAL349124:HHAL_1623-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00202
- InterPro:   IPR011876
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PANTHER:   PTHR10885
- PIRSF:   PIRSF018427
- TIGRFAMs:   TIGR02150

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: =5.3.3.2

Molecular weight: Translated: 19853; Mature: 19853

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS51462 NUDIX

Important sites: ACT_SITE 65-65 ACT_SITE 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHVVIVDPEGQRVGTEEKIRAHADGGTLHLAFCVFVFNPRGELLLQRRADSKYHFSGLW
CCCEEEECCCCCCCCCHHHEEEECCCCEEEEEEEEEEECCCCCEEEEECCCCCEEECCCC
SNTCCGHPRPGEGVTEAAERRLGEEFGFVTRLHPVAQFTYHAEDHHTGLAEYEYAHVLIG
CCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHEEECCCCCCCCCCCCEEEEEEEE
RAPTDQPAPDPLEIGAWEWAAPLRIQADTQQYPLRYTPWFRRLIQEQPVADWATG
CCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCEEECHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEHVVIVDPEGQRVGTEEKIRAHADGGTLHLAFCVFVFNPRGELLLQRRADSKYHFSGLW
CCCEEEECCCCCCCCCHHHEEEECCCCEEEEEEEEEEECCCCCEEEEECCCCCEEECCCC
SNTCCGHPRPGEGVTEAAERRLGEEFGFVTRLHPVAQFTYHAEDHHTGLAEYEYAHVLIG
CCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHEEECCCCCCCCCCCCEEEEEEEE
RAPTDQPAPDPLEIGAWEWAAPLRIQADTQQYPLRYTPWFRRLIQEQPVADWATG
CCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCEEECHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA