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The map label for this gene is dapB

Identifier: 121998256

GI number: 121998256

Start: 1594372

End: 1595175

Strand: Reverse

Name: dapB

Synonym: Hhal_1474

Alternate gene names: 121998256

Gene position: 1595175-1594372 (Counterclockwise)

Preceding gene: 121998257

Following gene: 121998248

Centisome position: 59.56

GC content: 70.77

Gene sequence:

>804_bases
ATGAGCCTGGGCATCGGCATCATCGGGGCCGGTGGTCGTATGGGCCGTATGCTGATCGAGGTCGTGCACCGGCAGCCGGG
GGTCCATGTGGCGGCAGCCACCGATCGGACCGGCGGCGAGGCCGTTGGCCGAGATGCCGGCGAGTTGGCCGGGCAGGGCT
CCTTGGGGGTGCCGATCGGTGACGATATCCCGGCCGCCGTGGCCGCCAGTGACGCGGTTATCGATTTCAGCCTGCCGGAG
GCGACCGAGACGGTGGCCGCCGCGTGTGCGGAGGCGGGTCGTCCGCTGGTGCTGGGGACCACCGGCCTGGGCGAGACCCA
GCGCGAGGCGGTCCACCGACTGGCGGAGCAAGTCGCCGTGATGCATGCGGCCAACTACTCCACTGGGGTCACGCTGCTGA
CCGCGCTGGTGGAGCAGGCGGCGCGCGCCATTGGCGTATACAGCGATATCGAGATCATCGAGGCCCACCACCGCCACAAG
GTGGACGCGCCGTCCGGGACCGCCCTGCGCCTGGGCGAGGCGGTGGCCGACGCCCTGGGGCGCGACCTGAGTCAGTGTGC
CGTCTACGGTCGCGAGGGACACACCGGCGAACGGGATCCCCAGACCATCGGCTTCGAGACCATCCGCGCCGGCGACATCG
TCGGTGATCACACGGTGCTCTTCGGTGGGGATGGCGAACGCGTCGAGCTGACCCACAAGGCCTCAAGCCGCACCACCTTC
GCCTCCGGCGCCGTGCGGGCCGCCGCCTGGGTGGTCGAGCAGCCGCCGGGGCTCTACGACATGCGCGACATGATCGGCGT
CTGA

Upstream 100 bases:

>100_bases
AGGAGTTCCAGGCGACCCTGCAGGACACCGGCGGCAAGCACCATCCGCACACCTCGTCGTGGCTGGACAAGGTCAAGCGC
TTCATCGAGGAGTGGCGGAT

Downstream 100 bases:

>100_bases
AGCCGCGGTGCGGTGTGGGGGCTGCCCCGCACCGCCCGCTGCTCAGGCGGCCGAACGTCCAGCGGGCAGGTCGGCCTGGT
AGCGCTGCAGGAAGTAGTCG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSLGIGIIGAGGRMGRMLIEVVHRQPGVHVAAATDRTGGEAVGRDAGELAGQGSLGVPIGDDIPAAVAASDAVIDFSLPE
ATETVAAACAEAGRPLVLGTTGLGETQREAVHRLAEQVAVMHAANYSTGVTLLTALVEQAARAIGVYSDIEIIEAHHRHK
VDAPSGTALRLGEAVADALGRDLSQCAVYGREGHTGERDPQTIGFETIRAGDIVGDHTVLFGGDGERVELTHKASSRTTF
ASGAVRAAAWVVEQPPGLYDMRDMIGV

Sequences:

>Translated_267_residues
MSLGIGIIGAGGRMGRMLIEVVHRQPGVHVAAATDRTGGEAVGRDAGELAGQGSLGVPIGDDIPAAVAASDAVIDFSLPE
ATETVAAACAEAGRPLVLGTTGLGETQREAVHRLAEQVAVMHAANYSTGVTLLTALVEQAARAIGVYSDIEIIEAHHRHK
VDAPSGTALRLGEAVADALGRDLSQCAVYGREGHTGERDPQTIGFETIRAGDIVGDHTVLFGGDGERVELTHKASSRTTF
ASGAVRAAAWVVEQPPGLYDMRDMIGV
>Mature_266_residues
SLGIGIIGAGGRMGRMLIEVVHRQPGVHVAAATDRTGGEAVGRDAGELAGQGSLGVPIGDDIPAAVAASDAVIDFSLPEA
TETVAAACAEAGRPLVLGTTGLGETQREAVHRLAEQVAVMHAANYSTGVTLLTALVEQAARAIGVYSDIEIIEAHHRHKV
DAPSGTALRLGEAVADALGRDLSQCAVYGREGHTGERDPQTIGFETIRAGDIVGDHTVLFGGDGERVELTHKASSRTTFA
SGAVRAAAWVVEQPPGLYDMRDMIGV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=264, Percent_Identity=54.1666666666667, Blast_Score=278, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_HALHL (A1WX29)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003043.1
- ProteinModelPortal:   A1WX29
- SMR:   A1WX29
- STRING:   A1WX29
- GeneID:   4710003
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1474
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   A1WX29
- BioCyc:   HHAL349124:HHAL_1474-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27513; Mature: 27382

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGIGIIGAGGRMGRMLIEVVHRQPGVHVAAATDRTGGEAVGRDAGELAGQGSLGVPIG
CCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCHHHHCCCCCCCCCCC
DDIPAAVAASDAVIDFSLPEATETVAAACAEAGRPLVLGTTGLGETQREAVHRLAEQVAV
CCCCHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
MHAANYSTGVTLLTALVEQAARAIGVYSDIEIIEAHHRHKVDAPSGTALRLGEAVADALG
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
RDLSQCAVYGREGHTGERDPQTIGFETIRAGDIVGDHTVLFGGDGERVELTHKASSRTTF
CCHHHHHHCCCCCCCCCCCCCCCCHHHEECCCEECCCEEEECCCCCEEEEEECCCCCCCH
ASGAVRAAAWVVEQPPGLYDMRDMIGV
HHCHHHHHHEEECCCCCCHHHHHHHCC
>Mature Secondary Structure 
SLGIGIIGAGGRMGRMLIEVVHRQPGVHVAAATDRTGGEAVGRDAGELAGQGSLGVPIG
CCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCHHHHCCCCCCCCCCC
DDIPAAVAASDAVIDFSLPEATETVAAACAEAGRPLVLGTTGLGETQREAVHRLAEQVAV
CCCCHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
MHAANYSTGVTLLTALVEQAARAIGVYSDIEIIEAHHRHKVDAPSGTALRLGEAVADALG
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
RDLSQCAVYGREGHTGERDPQTIGFETIRAGDIVGDHTVLFGGDGERVELTHKASSRTTF
CCHHHHHHCCCCCCCCCCCCCCCCHHHEECCCEECCCEEEECCCCCEEEEEECCCCCCCH
ASGAVRAAAWVVEQPPGLYDMRDMIGV
HHCHHHHHHEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA