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The map label for this gene is tsf

Identifier: 121998247

GI number: 121998247

Start: 1580565

End: 1581440

Strand: Reverse

Name: tsf

Synonym: Hhal_1465

Alternate gene names: 121998247

Gene position: 1581440-1580565 (Counterclockwise)

Preceding gene: 121998248

Following gene: 121998246

Centisome position: 59.04

GC content: 65.07

Gene sequence:

>876_bases
ATGTCCGTATCTGCAAACCTGGTCAAGCAGCTCCGTGAGCGCACCGGCTCCGGCATGATGGAGTGCAAGAAGGCGCTGGT
GGAGGTGGACGGTGACCTCGAGGCCGCCGCCGAGCTCATGCGCAAGAAGGGCCTGGCCAAGGCCGACAAGAAGGCCGATC
GCGTCGCTGCCGAGGGCCGCGTCGTGGCGGCCCGTTCCGAAGACGGTAAGTCGGGCGTGCTTGTGGAGGTTAACTCCGAG
ACCGACTTTGTCGGCAACGGGGACGAGTTCCGGGCCTTCGCCGAGTCCGTGGCCCAGCGCGCCCTGGATTCCAAGGTCGA
GGACCTGGACAGCCTGTTGGCTAGCGAGGTCGATGGCAAGTCGGTGGAGACCCTGCGCCAGGAGATGGTCGCCCAACTTG
GCGAGAACATCGAGGTGCGCCGTTTCATCCGCTACGCTGGGGACCATCAGGTGGCTCAGTACCTGCACGGTGCCCGGATC
GGCGTTATGGTCGAGGTCCAGGGCGGCGATGAACAGCTCGGGCGGGACCTGGCGATGCACATCGCGGCCTCCTCGCCGGT
CTGCGTCAGCCCCGATGACGTGCCTGCGGATCAGCTGTCCTCCGAGAAGGAAGTGCTGCTTGCGCAGGCCCGCGAGAGCG
GCAAGCCGGAAGAGATCGTCGAGAAGATGGTCGAAGGCCGGCTCAAGAAACACCTGAGCGAGATCACGCTGCTCGGCCAA
CCCTTCGTCAAGGACCCGGATCAGACGGTCGGGGACCTGCTCAAGGCCAAGGGCGCGGAAGTGACCCGTTTCGCGCGCTA
CGAGGTCGGCGAAGGCAAGGAGAAGAAAGACGAGAGCTTCGCTGACGAGGTGATGGCGCAAGTCCGCGACTCCTGA

Upstream 100 bases:

>100_bases
CCGTAATCGAGGCGAAGCAGGCGTCGAGTCACGCCGCTGCTGCCGGCAAGGACGACTTCGTCGAGATCAACGACACCGCA
TCCTGAGGGGGCAAGCACAG

Downstream 100 bases:

>100_bases
GCCCGGGCGGCGTTACCAGCAACGGCGGTGCCCGGGTGGCCCGGGCACCGCGCCCGCTCACTAAAAGGCCGGAGTCATGA
CGGTGCCGCACTATCGCCGG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSVSANLVKQLRERTGSGMMECKKALVEVDGDLEAAAELMRKKGLAKADKKADRVAAEGRVVAARSEDGKSGVLVEVNSE
TDFVGNGDEFRAFAESVAQRALDSKVEDLDSLLASEVDGKSVETLRQEMVAQLGENIEVRRFIRYAGDHQVAQYLHGARI
GVMVEVQGGDEQLGRDLAMHIAASSPVCVSPDDVPADQLSSEKEVLLAQARESGKPEEIVEKMVEGRLKKHLSEITLLGQ
PFVKDPDQTVGDLLKAKGAEVTRFARYEVGEGKEKKDESFADEVMAQVRDS

Sequences:

>Translated_291_residues
MSVSANLVKQLRERTGSGMMECKKALVEVDGDLEAAAELMRKKGLAKADKKADRVAAEGRVVAARSEDGKSGVLVEVNSE
TDFVGNGDEFRAFAESVAQRALDSKVEDLDSLLASEVDGKSVETLRQEMVAQLGENIEVRRFIRYAGDHQVAQYLHGARI
GVMVEVQGGDEQLGRDLAMHIAASSPVCVSPDDVPADQLSSEKEVLLAQARESGKPEEIVEKMVEGRLKKHLSEITLLGQ
PFVKDPDQTVGDLLKAKGAEVTRFARYEVGEGKEKKDESFADEVMAQVRDS
>Mature_290_residues
SVSANLVKQLRERTGSGMMECKKALVEVDGDLEAAAELMRKKGLAKADKKADRVAAEGRVVAARSEDGKSGVLVEVNSET
DFVGNGDEFRAFAESVAQRALDSKVEDLDSLLASEVDGKSVETLRQEMVAQLGENIEVRRFIRYAGDHQVAQYLHGARIG
VMVEVQGGDEQLGRDLAMHIAASSPVCVSPDDVPADQLSSEKEVLLAQARESGKPEEIVEKMVEGRLKKHLSEITLLGQP
FVKDPDQTVGDLLKAKGAEVTRFARYEVGEGKEKKDESFADEVMAQVRDS

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=304, Percent_Identity=26.6447368421053, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786366, Length=289, Percent_Identity=50.5190311418685, Blast_Score=264, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI17561440, Length=309, Percent_Identity=25.5663430420712, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19921466, Length=290, Percent_Identity=28.6206896551724, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_HALHL (A1WX20)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003034.1
- ProteinModelPortal:   A1WX20
- SMR:   A1WX20
- STRING:   A1WX20
- GeneID:   4710660
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1465
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   A1WX20
- ProtClustDB:   PRK09377
- BioCyc:   HHAL349124:HHAL_1465-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31645; Mature: 31514

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSANLVKQLRERTGSGMMECKKALVEVDGDLEAAAELMRKKGLAKADKKADRVAAEGR
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCC
VVAARSEDGKSGVLVEVNSETDFVGNGDEFRAFAESVAQRALDSKVEDLDSLLASEVDGK
EEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVETLRQEMVAQLGENIEVRRFIRYAGDHQVAQYLHGARIGVMVEVQGGDEQLGRDLAMH
HHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
IAASSPVCVSPDDVPADQLSSEKEVLLAQARESGKPEEIVEKMVEGRLKKHLSEITLLGQ
HHCCCCCEECCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PFVKDPDQTVGDLLKAKGAEVTRFARYEVGEGKEKKDESFADEVMAQVRDS
CCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVSANLVKQLRERTGSGMMECKKALVEVDGDLEAAAELMRKKGLAKADKKADRVAAEGR
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCC
VVAARSEDGKSGVLVEVNSETDFVGNGDEFRAFAESVAQRALDSKVEDLDSLLASEVDGK
EEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVETLRQEMVAQLGENIEVRRFIRYAGDHQVAQYLHGARIGVMVEVQGGDEQLGRDLAMH
HHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
IAASSPVCVSPDDVPADQLSSEKEVLLAQARESGKPEEIVEKMVEGRLKKHLSEITLLGQ
HHCCCCCEECCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PFVKDPDQTVGDLLKAKGAEVTRFARYEVGEGKEKKDESFADEVMAQVRDS
CCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA