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The map label for this gene is cbiX [H]

Identifier: 121998132

GI number: 121998132

Start: 1459366

End: 1460190

Strand: Reverse

Name: cbiX [H]

Synonym: Hhal_1350

Alternate gene names: 121998132

Gene position: 1460190-1459366 (Counterclockwise)

Preceding gene: 121998133

Following gene: 121998131

Centisome position: 54.52

GC content: 68.36

Gene sequence:

>825_bases
ATGACTGACTGTATCCTGTTGATTGGGCATGGCTCGCGCCAGGAGGACGGCAACGAGGAGATCCGCCGGTTCGCCGACCT
GCTGGCCGAGCACTACCCGGATTGGCTGCTGGAGACCTGTTTCATCGAGTTCGCGGATCCGCTGCTTGGCGAGGGGCTGG
ATCGGGCCGCGGCGCGGGCGGATCGGGTCATCGCGGTCCCACTGATCCTTAACGCCGCCGGGCACGTGAAGCTCGAGGTG
CCCGAGCAGATCGAGGCTGCCCGTGCCCGGCACCCGGGGGTCGATTTCCGTCTGGCGCGCCATCTGGGCGTGAGTGAAAC
GACGCTGGGCCTGGTCGAGCGCCGCCTGCGTGACGCCATGCAGGCCCTGAGTGTGCCCGATCCGCGGACCACCGGGGTGA
TCCTGCTGGGTCGCGGATCCTCGGATCGTACGGCCAACGGGGAGTTGGCGCGGCTGGGCCGCTGGCTCTACGAGGGCGGC
GAGCACGAACTGGTCGATATCGCCTTCACCGGCGTCACCCACCCCCGCCTGGAGGCCGTGGTGCGGCGTCACTCCCTGTT
GGGCATGACGCAGCAGGTGGTCCTGCCGTATTACCTGTTCACCGGGCGGCTGATCGAGCGTATTGAGCAGCAGGTGGCGC
GTCTGCGGGTTCAGTACCCGCAGACGGCGTTCGCCCTGGCGGATTACCTCGGTTTTGAACCGGAGGTCTTCGCACTGATC
GCCCAGCGGGTGGAGGAGGCGCGTGCGGGACAGGCGATGCTCGAGTGCGACGGCTGCCCGCACCGCGCGGCGGCCGCGCA
CCACCACCATCACCACCACCACTGA

Upstream 100 bases:

>100_bases
GCTCGGGGCGCGGGAGGCGGCACCGGCGGCGCGCTCACGGCTTTACGACCCCGGTTTCGGCCACCGTTTCCGCCGCCGCG
AAAATTGAGGAACGACATGC

Downstream 100 bases:

>100_bases
AGAGGTGCGAGGATGTCTCGCGAGCCGTCCGTGACCGAGCAGCAGACCGCCTCCGGGCGCCAGATCGAGGCGTGCTCCTT
CGCCCGCGTCGACGCCGAGG

Product: cobalamin (vitamin B12) biosynthesis CbiX protein

Products: NA

Alternate protein names: CbiXL [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTDCILLIGHGSRQEDGNEEIRRFADLLAEHYPDWLLETCFIEFADPLLGEGLDRAAARADRVIAVPLILNAAGHVKLEV
PEQIEAARARHPGVDFRLARHLGVSETTLGLVERRLRDAMQALSVPDPRTTGVILLGRGSSDRTANGELARLGRWLYEGG
EHELVDIAFTGVTHPRLEAVVRRHSLLGMTQQVVLPYYLFTGRLIERIEQQVARLRVQYPQTAFALADYLGFEPEVFALI
AQRVEEARAGQAMLECDGCPHRAAAAHHHHHHHH

Sequences:

>Translated_274_residues
MTDCILLIGHGSRQEDGNEEIRRFADLLAEHYPDWLLETCFIEFADPLLGEGLDRAAARADRVIAVPLILNAAGHVKLEV
PEQIEAARARHPGVDFRLARHLGVSETTLGLVERRLRDAMQALSVPDPRTTGVILLGRGSSDRTANGELARLGRWLYEGG
EHELVDIAFTGVTHPRLEAVVRRHSLLGMTQQVVLPYYLFTGRLIERIEQQVARLRVQYPQTAFALADYLGFEPEVFALI
AQRVEEARAGQAMLECDGCPHRAAAAHHHHHHHH
>Mature_273_residues
TDCILLIGHGSRQEDGNEEIRRFADLLAEHYPDWLLETCFIEFADPLLGEGLDRAAARADRVIAVPLILNAAGHVKLEVP
EQIEAARARHPGVDFRLARHLGVSETTLGLVERRLRDAMQALSVPDPRTTGVILLGRGSSDRTANGELARLGRWLYEGGE
HELVDIAFTGVTHPRLEAVVRRHSLLGMTQQVVLPYYLFTGRLIERIEQQVARLRVQYPQTAFALADYLGFEPEVFALIA
QRVEEARAGQAMLECDGCPHRAAAAHHHHHHHH

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG2138

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. CbiXL subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002762 [H]

Pfam domain/function: PF01903 CbiX [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 30630; Mature: 30499

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDCILLIGHGSRQEDGNEEIRRFADLLAEHYPDWLLETCFIEFADPLLGEGLDRAAARA
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
DRVIAVPLILNAAGHVKLEVPEQIEAARARHPGVDFRLARHLGVSETTLGLVERRLRDAM
CCEEEEHHHHCCCCCEEEECHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
QALSVPDPRTTGVILLGRGSSDRTANGELARLGRWLYEGGEHELVDIAFTGVTHPRLEAV
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
VRRHSLLGMTQQVVLPYYLFTGRLIERIEQQVARLRVQYPQTAFALADYLGFEPEVFALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH
AQRVEEARAGQAMLECDGCPHRAAAAHHHHHHHH
HHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
TDCILLIGHGSRQEDGNEEIRRFADLLAEHYPDWLLETCFIEFADPLLGEGLDRAAARA
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
DRVIAVPLILNAAGHVKLEVPEQIEAARARHPGVDFRLARHLGVSETTLGLVERRLRDAM
CCEEEEHHHHCCCCCEEEECHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
QALSVPDPRTTGVILLGRGSSDRTANGELARLGRWLYEGGEHELVDIAFTGVTHPRLEAV
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
VRRHSLLGMTQQVVLPYYLFTGRLIERIEQQVARLRVQYPQTAFALADYLGFEPEVFALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH
AQRVEEARAGQAMLECDGCPHRAAAAHHHHHHHH
HHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9742225; 12917443 [H]