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The map label for this gene is cobL [H]

Identifier: 121998130

GI number: 121998130

Start: 1457393

End: 1458688

Strand: Reverse

Name: cobL [H]

Synonym: Hhal_1348

Alternate gene names: 121998130

Gene position: 1458688-1457393 (Counterclockwise)

Preceding gene: 121998131

Following gene: 121998129

Centisome position: 54.46

GC content: 73.3

Gene sequence:

>1296_bases
GTGACCCCGGTCTGCACCATCGTCGGTGTGCTCGATGACGGTCCCGACGGGCTGGCACCGGTGGCCCGTGAGGCCATTGC
CGGCGCCGATCTGCTCATCGGCGGACGCCGGGTCCTCGAGGGCTTTGCCCCCCTGGCCCCCGGAGCACAACGCCGGGACC
TGACCGGCGCCGTGGCGGAGGTGCCGGCCTGGATCGAGACCGCGGCCGCCGAGGGGCAGCGCGTGGTGGTCCTCGCCAGT
GGCGATCCGCTCTGCCACGGCATCGGTGAGCGGATCACCAGCCACCTCGGGGCCGAGCGCTGCCGGGTCCTGCCGGCACC
GTCCCTGGTGCAGTTGGCGTGCGCCCGGCTCGGTTGGCCCGTGGCGCAGACCGCCATCGCCTCGGTCCACGGCCCAGTGG
CTGGCGACTGGTCGGCGCAGACGGCGGCGCCGGAGCATCCGCTCAGCGGCGTGCTGCGCGCGCTGGCCGATCACGACCGG
GTGGCGGTCTACACCACCGGCGAGAACGGTGCCGACTGGTTGGCCCGGCAGCTGCAGGCAGTGGGGTATCGCGACACCGA
GCTGGAGGTGGCAGCGGTCGCCCGCATTGGCCGGGAGGACGAGGCGCTCTACCCGCCGGCCCCCCTTGGCACCGCCGCGG
CGCGCCACTATCCGCAGCCCCATGTCGCCCTGGTGCGGCGACGGGCGACGCTGGACTGGCCGTTCGCGGGCGTTGACGAG
GCGTTCGCCCAGCGTCGGCCCCAGCGCGGTCTGATCACCAAGCGGGAAGTGCGCGCGGTTACGCTCGCCGGCCTGGCGCT
GACCCCGGACAGCCGGGTCTGGGATATCGGCACCGGCTCCGGTGCGGTGGCTCTCGAGGCCGCGCGGCTCTGCCCCCGGG
GGCATGTCTGGGCGATGGAGCGTCGTGCCGAGGATCTGGCCATCGCCGAGGAGAACCGGCGCCGTCGCAGGGTGGGCAAC
GTCACCCTCCACCACGGTCGGGCGCCGCAGGGGCTCGACGCCTGGCTGGATCCGGATGCAGTCTTCATCGGTGGCTCGGG
CGGGGCGCTGGGCGAACTGATCGACCTCTGCCTACGGCGGCTGCGCCCGGCGGGGCGGTTGGTGATCAACCTGGTCACCC
TGGAGAATCTGCACCAGGCCACGGCCCGGCTCGACGCTGCCGCGGCGGCCGGCGTCGCGGACTGGGAAGCCATCCAGCTG
CAAGCCCATCGCAGCGGTGAGCTGGCCGGGATGCGCACGTTCCGTGCTGAGAACCCGGTCTGGATCCTCATGGCGAACAA
GACGGAGAGCGCATGA

Upstream 100 bases:

>100_bases
AGCAGGTGCCGTGGATCGCCACCGCCGGGCGCAAGGGCGGGACGCCGCCGGTGGTGGCCTGTCTGCACGCCCTGCTCGCC
CTGGCCGAGGAGGGAGACGG

Downstream 100 bases:

>100_bases
CGACGTCGGCAGGGCGATTGATCGGGGTTTCCCTCGGCCCCGGGGACCCGGGCTGGATCACCCGCCGGGCCTGGCAGGTC
CTCCAGGGGGAGGCGCGCTG

Product: precorrin-6y C5,15-methyltransferase subunit CbiT

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTPVCTIVGVLDDGPDGLAPVAREAIAGADLLIGGRRVLEGFAPLAPGAQRRDLTGAVAEVPAWIETAAAEGQRVVVLAS
GDPLCHGIGERITSHLGAERCRVLPAPSLVQLACARLGWPVAQTAIASVHGPVAGDWSAQTAAPEHPLSGVLRALADHDR
VAVYTTGENGADWLARQLQAVGYRDTELEVAAVARIGREDEALYPPAPLGTAAARHYPQPHVALVRRRATLDWPFAGVDE
AFAQRRPQRGLITKREVRAVTLAGLALTPDSRVWDIGTGSGAVALEAARLCPRGHVWAMERRAEDLAIAEENRRRRRVGN
VTLHHGRAPQGLDAWLDPDAVFIGGSGGALGELIDLCLRRLRPAGRLVINLVTLENLHQATARLDAAAAAGVADWEAIQL
QAHRSGELAGMRTFRAENPVWILMANKTESA

Sequences:

>Translated_431_residues
MTPVCTIVGVLDDGPDGLAPVAREAIAGADLLIGGRRVLEGFAPLAPGAQRRDLTGAVAEVPAWIETAAAEGQRVVVLAS
GDPLCHGIGERITSHLGAERCRVLPAPSLVQLACARLGWPVAQTAIASVHGPVAGDWSAQTAAPEHPLSGVLRALADHDR
VAVYTTGENGADWLARQLQAVGYRDTELEVAAVARIGREDEALYPPAPLGTAAARHYPQPHVALVRRRATLDWPFAGVDE
AFAQRRPQRGLITKREVRAVTLAGLALTPDSRVWDIGTGSGAVALEAARLCPRGHVWAMERRAEDLAIAEENRRRRRVGN
VTLHHGRAPQGLDAWLDPDAVFIGGSGGALGELIDLCLRRLRPAGRLVINLVTLENLHQATARLDAAAAAGVADWEAIQL
QAHRSGELAGMRTFRAENPVWILMANKTESA
>Mature_430_residues
TPVCTIVGVLDDGPDGLAPVAREAIAGADLLIGGRRVLEGFAPLAPGAQRRDLTGAVAEVPAWIETAAAEGQRVVVLASG
DPLCHGIGERITSHLGAERCRVLPAPSLVQLACARLGWPVAQTAIASVHGPVAGDWSAQTAAPEHPLSGVLRALADHDRV
AVYTTGENGADWLARQLQAVGYRDTELEVAAVARIGREDEALYPPAPLGTAAARHYPQPHVALVRRRATLDWPFAGVDEA
FAQRRPQRGLITKREVRAVTLAGLALTPDSRVWDIGTGSGAVALEAARLCPRGHVWAMERRAEDLAIAEENRRRRRVGNV
TLHHGRAPQGLDAWLDPDAVFIGGSGGALGELIDLCLRRLRPAGRLVINLVTLENLHQATARLDAAAAAGVADWEAIQLQ
AHRSGELAGMRTFRAENPVWILMANKTESA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 45815; Mature: 45684

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVCTIVGVLDDGPDGLAPVAREAIAGADLLIGGRRVLEGFAPLAPGAQRRDLTGAVAE
CCCCEEEEEEECCCCCCHHHHHHHHHCCCHHEECCHHHHHHCCCCCCCCCCCCCCHHHHH
VPAWIETAAAEGQRVVVLASGDPLCHGIGERITSHLGAERCRVLPAPSLVQLACARLGWP
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCHHHHEECCCCHHHHHHHHHHCCH
VAQTAIASVHGPVAGDWSAQTAAPEHPLSGVLRALADHDRVAVYTTGENGADWLARQLQA
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHH
VGYRDTELEVAAVARIGREDEALYPPAPLGTAAARHYPQPHVALVRRRATLDWPFAGVDE
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCHHH
AFAQRRPQRGLITKREVRAVTLAGLALTPDSRVWDIGTGSGAVALEAARLCPRGHVWAME
HHHHCCCCCCCCCHHHHHEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHCCCCCEEHHH
RRAEDLAIAEENRRRRRVGNVTLHHGRAPQGLDAWLDPDAVFIGGSGGALGELIDLCLRR
HCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
LRPAGRLVINLVTLENLHQATARLDAAAAAGVADWEAIQLQAHRSGELAGMRTFRAENPV
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHEEEECCCCE
WILMANKTESA
EEEEECCCCCC
>Mature Secondary Structure 
TPVCTIVGVLDDGPDGLAPVAREAIAGADLLIGGRRVLEGFAPLAPGAQRRDLTGAVAE
CCCEEEEEEECCCCCCHHHHHHHHHCCCHHEECCHHHHHHCCCCCCCCCCCCCCHHHHH
VPAWIETAAAEGQRVVVLASGDPLCHGIGERITSHLGAERCRVLPAPSLVQLACARLGWP
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCHHHHEECCCCHHHHHHHHHHCCH
VAQTAIASVHGPVAGDWSAQTAAPEHPLSGVLRALADHDRVAVYTTGENGADWLARQLQA
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHH
VGYRDTELEVAAVARIGREDEALYPPAPLGTAAARHYPQPHVALVRRRATLDWPFAGVDE
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCHHH
AFAQRRPQRGLITKREVRAVTLAGLALTPDSRVWDIGTGSGAVALEAARLCPRGHVWAME
HHHHCCCCCCCCCHHHHHEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHCCCCCEEHHH
RRAEDLAIAEENRRRRRVGNVTLHHGRAPQGLDAWLDPDAVFIGGSGGALGELIDLCLRR
HCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
LRPAGRLVINLVTLENLHQATARLDAAAAAGVADWEAIQLQAHRSGELAGMRTFRAENPV
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHEEEECCCCE
WILMANKTESA
EEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]