Click here to switch to the map view.

The map label for this gene is cobI [H]

Identifier: 121998129

GI number: 121998129

Start: 1456644

End: 1457396

Strand: Reverse

Name: cobI [H]

Synonym: Hhal_1347

Alternate gene names: 121998129

Gene position: 1457396-1456644 (Counterclockwise)

Preceding gene: 121998130

Following gene: 121998128

Centisome position: 54.41

GC content: 70.25

Gene sequence:

>753_bases
ATGACGACGTCGGCAGGGCGATTGATCGGGGTTTCCCTCGGCCCCGGGGACCCGGGCTGGATCACCCGCCGGGCCTGGCA
GGTCCTCCAGGGGGAGGCGCGCTGGGCCTATCCGGTGCGCGCCGAGGGGCAGTCCAGCTACGCCCTGGAGATTGTCGAGC
GGGGCGGATTGGTGGCGCCGGCCGACGCCATGCCCCTCGTCTTTCCGATGACCCGCGATCCGGCCACCCTGGCGTTGCAT
TGGGCGCAGGCGGCGAAGGCGGTGGCGGCGACTCTGGGCCAGGGGCAGGACGTCGCCTTCCTGGTCGAGGGGGATGCCTC
CACGTACGCGACCTTTGGCCACTTGGCGCGCACGGTCACCGCGGAGGCCCCCGGCGCTGAGGTCGAGACGATCCCCGGGG
TGGCCTCCTTTCTGGCAGCGCCGGCGCGGGTCGGCTGGCCGCTGGCCAGCCAGGACGATGCCTTGGCGGTGCTGCCCGGT
GGCTACGGCATGGAGACCGTGGAGCGGCTGCTGCCGGAGGTCGATACGCTGGTGCTGCTCAAGGTCAAACCGCTGCTTGC
AGAGGTGATCGACCTGCTCGAGGAGCAGGGGTTGAGTGACGCCAGCGTCTTCGTCGAGCGCGTGGGGACTCCGCAGGAGC
GAGTGGTCACCGACATCGCCCGATTGCGCGGCGAGACGGTTCACTATCTGTCGTTGCTGATGATTTGCAAGGGCCGCGCC
GATTCGCGCAGCGAAGGAGCCGGAGCCGGGTGA

Upstream 100 bases:

>100_bases
TCCAGCTGCAAGCCCATCGCAGCGGTGAGCTGGCCGGGATGCGCACGTTCCGTGCTGAGAACCCGGTCTGGATCCTCATG
GCGAACAAGACGGAGAGCGC

Downstream 100 bases:

>100_bases
GGGAGACGGGCGAAGGGGTGTTGCTGGTGGTGGTGACCCGCGGCGGTGCGGCCAGCGCAGCCCGCCTGGCCGGGATCTGG
CCCGAAGCCGAGATCCTGGT

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTTSAGRLIGVSLGPGDPGWITRRAWQVLQGEARWAYPVRAEGQSSYALEIVERGGLVAPADAMPLVFPMTRDPATLALH
WAQAAKAVAATLGQGQDVAFLVEGDASTYATFGHLARTVTAEAPGAEVETIPGVASFLAAPARVGWPLASQDDALAVLPG
GYGMETVERLLPEVDTLVLLKVKPLLAEVIDLLEEQGLSDASVFVERVGTPQERVVTDIARLRGETVHYLSLLMICKGRA
DSRSEGAGAG

Sequences:

>Translated_250_residues
MTTSAGRLIGVSLGPGDPGWITRRAWQVLQGEARWAYPVRAEGQSSYALEIVERGGLVAPADAMPLVFPMTRDPATLALH
WAQAAKAVAATLGQGQDVAFLVEGDASTYATFGHLARTVTAEAPGAEVETIPGVASFLAAPARVGWPLASQDDALAVLPG
GYGMETVERLLPEVDTLVLLKVKPLLAEVIDLLEEQGLSDASVFVERVGTPQERVVTDIARLRGETVHYLSLLMICKGRA
DSRSEGAGAG
>Mature_249_residues
TTSAGRLIGVSLGPGDPGWITRRAWQVLQGEARWAYPVRAEGQSSYALEIVERGGLVAPADAMPLVFPMTRDPATLALHW
AQAAKAVAATLGQGQDVAFLVEGDASTYATFGHLARTVTAEAPGAEVETIPGVASFLAAPARVGWPLASQDDALAVLPGG
YGMETVERLLPEVDTLVLLKVKPLLAEVIDLLEEQGLSDASVFVERVGTPQERVVTDIARLRGETVHYLSLLMICKGRAD
SRSEGAGAG

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 26326; Mature: 26195

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSAGRLIGVSLGPGDPGWITRRAWQVLQGEARWAYPVRAEGQSSYALEIVERGGLVAP
CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEECCEECCCCCCHHHHHHHCCCEECC
ADAMPLVFPMTRDPATLALHWAQAAKAVAATLGQGQDVAFLVEGDASTYATFGHLARTVT
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHC
AEAPGAEVETIPGVASFLAAPARVGWPLASQDDALAVLPGGYGMETVERLLPEVDTLVLL
CCCCCCCCCCCCHHHHHHHCHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEE
KVKPLLAEVIDLLEEQGLSDASVFVERVGTPQERVVTDIARLRGETVHYLSLLMICKGRA
EHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
DSRSEGAGAG
CCCCCCCCCC
>Mature Secondary Structure 
TTSAGRLIGVSLGPGDPGWITRRAWQVLQGEARWAYPVRAEGQSSYALEIVERGGLVAP
CCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEECCEECCCCCCHHHHHHHCCCEECC
ADAMPLVFPMTRDPATLALHWAQAAKAVAATLGQGQDVAFLVEGDASTYATFGHLARTVT
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHC
AEAPGAEVETIPGVASFLAAPARVGWPLASQDDALAVLPGGYGMETVERLLPEVDTLVLL
CCCCCCCCCCCCHHHHHHHCHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEE
KVKPLLAEVIDLLEEQGLSDASVFVERVGTPQERVVTDIARLRGETVHYLSLLMICKGRA
EHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
DSRSEGAGAG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]