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The map label for this gene is tolQ [H]

Identifier: 121998038

GI number: 121998038

Start: 1354511

End: 1355143

Strand: Reverse

Name: tolQ [H]

Synonym: Hhal_1248

Alternate gene names: 121998038

Gene position: 1355143-1354511 (Counterclockwise)

Preceding gene: 121998039

Following gene: 121998037

Centisome position: 50.59

GC content: 67.61

Gene sequence:

>633_bases
ATGCTTGAGCTCATCCAGGCCGGTGGCTGGCTGATGATACCGATCCTCATCGGTTCCGTCCTGGCCCTGGCCATCATCAT
CGAGCGATTCTGGACCCTGCAGCAGAGACGCATCCTCCCGGAGCCGCTGCGCGGGCGGGCCTGGCGCCTGGCGCAGGAGC
ACGAGTTAGAGGCCCACCATCTCGAGACCCTCAAGGAGAGCTCGCCCCTCGGTCGGATCCTGGCGGCCGGCCTGGCCAAT
CGGCACCACGGCCGCAGTGTCATGGCCGAGGCGATCGAGGATGCCGGCCGCCATGAAGCCCACCGCCTCGAGCGCTACCT
GAACACGCTGGGCACCATCGCGGCGATCAGCCCGCTGCTCGGGCTCCTGGGCACCGTGATCGGCATGATCAAGGTCTTCG
GGGCGATCAGTGCCGAGGGTCTGGGTGATATGGCCGCCCTCTCGGGGGGGATCGCCGAGGCCCTGATCACCACCGCATCG
GGGTTGACCATCGCCATCCCGGCGCTGATGGCGTATCGCTACCTGCGCGGCCTGGTCGACGAACGGGTAGTCGAAATGGA
GCAGGAGGCGATGCTTCTGCTCGAGGCCAGCGATCCTGAGCGTCCGGTACAGCGAGCCCGGGGGGCCGCTTGA

Upstream 100 bases:

>100_bases
TCAGGCCAGTCCGGCTGCGTTGGCGCCCGGGATGCTTTAAAATCCGCCGCCACGCCCACCCGTTCCGGACTGAGCGCCTT
GACCGACCCGGGGAGTGATC

Downstream 100 bases:

>100_bases
ACCTGCGGCGCCGGCAACGCCGGGACGAACCGGAGCTCAATCTGACGCCGTTGATCGACGTCGTCTTCCTGTTGCTGATC
TTCTTCATGGTGACCACGAC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MLELIQAGGWLMIPILIGSVLALAIIIERFWTLQQRRILPEPLRGRAWRLAQEHELEAHHLETLKESSPLGRILAAGLAN
RHHGRSVMAEAIEDAGRHEAHRLERYLNTLGTIAAISPLLGLLGTVIGMIKVFGAISAEGLGDMAALSGGIAEALITTAS
GLTIAIPALMAYRYLRGLVDERVVEMEQEAMLLLEASDPERPVQRARGAA

Sequences:

>Translated_210_residues
MLELIQAGGWLMIPILIGSVLALAIIIERFWTLQQRRILPEPLRGRAWRLAQEHELEAHHLETLKESSPLGRILAAGLAN
RHHGRSVMAEAIEDAGRHEAHRLERYLNTLGTIAAISPLLGLLGTVIGMIKVFGAISAEGLGDMAALSGGIAEALITTAS
GLTIAIPALMAYRYLRGLVDERVVEMEQEAMLLLEASDPERPVQRARGAA
>Mature_210_residues
MLELIQAGGWLMIPILIGSVLALAIIIERFWTLQQRRILPEPLRGRAWRLAQEHELEAHHLETLKESSPLGRILAAGLAN
RHHGRSVMAEAIEDAGRHEAHRLERYLNTLGTIAAISPLLGLLGTVIGMIKVFGAISAEGLGDMAALSGGIAEALITTAS
GLTIAIPALMAYRYLRGLVDERVVEMEQEAMLLLEASDPERPVQRARGAA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=189, Percent_Identity=34.3915343915344, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789381, Length=224, Percent_Identity=29.0178571428571, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 22798; Mature: 22798

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELIQAGGWLMIPILIGSVLALAIIIERFWTLQQRRILPEPLRGRAWRLAQEHELEAHH
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LETLKESSPLGRILAAGLANRHHGRSVMAEAIEDAGRHEAHRLERYLNTLGTIAAISPLL
HHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GLLGTVIGMIKVFGAISAEGLGDMAALSGGIAEALITTASGLTIAIPALMAYRYLRGLVD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ERVVEMEQEAMLLLEASDPERPVQRARGAA
HHHHHHHHHHHHEEECCCCHHHHHHHCCCC
>Mature Secondary Structure
MLELIQAGGWLMIPILIGSVLALAIIIERFWTLQQRRILPEPLRGRAWRLAQEHELEAHH
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LETLKESSPLGRILAAGLANRHHGRSVMAEAIEDAGRHEAHRLERYLNTLGTIAAISPLL
HHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GLLGTVIGMIKVFGAISAEGLGDMAALSGGIAEALITTASGLTIAIPALMAYRYLRGLVD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ERVVEMEQEAMLLLEASDPERPVQRARGAA
HHHHHHHHHHHHEEECCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]