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The map label for this gene is moaB [H]

Identifier: 121997929

GI number: 121997929

Start: 1237969

End: 1238508

Strand: Reverse

Name: moaB [H]

Synonym: Hhal_1138

Alternate gene names: 121997929

Gene position: 1238508-1237969 (Counterclockwise)

Preceding gene: 121997930

Following gene: 121997926

Centisome position: 46.24

GC content: 70.0

Gene sequence:

>540_bases
GTGGCAGGACATGCCGGCGACGTGTTTCAGCCCCTGGCCCTGGCGGTGCTCACTGTTTCCGATACCCGCGGGCTGGCCGA
GGACACCTCCGGGGCGGCCCTGGCTGAGCGTCTGCAGGGGGCCGGTCACGTTTTGGCTGGGCGCGTGATCGCCCCGGACG
ACCGCTATCGGATCCGCGCCGAGGTCTCGGCATGGATCGCCGATTCCCGGGTGGACGGGGTACTGATCAGTGGCGGCACG
GGGCTGACAGCGCGCGATGTGACGCCGGAGGCGGTGCGTCCGCTCTTGGATCGCGAGATCCCCGGTTTCGGCGAGCTGTT
TCGGCAGCGCTCCTTCGAGGAGATCGGCAACGCGACCCTGCAGTCACGGGCCGTGGCGGGTGTGGCCAACGCCACGCTGA
TCTTCGCCCTGCCCGGATCCACCGGCGGATGCTGTACCGCCTGGGATCGGGTCCTGGCCGATCAGCTGGATGCCCGCACC
CGCCCATGCAACTTCGCGACCCTGCTGCCGCGCATGCGCGCCTCCGAACCCTTGGCGTAG

Upstream 100 bases:

>100_bases
TGGTCTGGACGTTCTTTCTCTGGGATCCCGAGGAGATGATCCCGCCGGCCACCGAGCGTGAGGCACCTGTCCACCCCGAG
GAGCAGCAGGAGTAATCAAC

Downstream 100 bases:

>100_bases
CGGCCGAAATTCGGTAGGCTACACCTCCTACCGCCCGTAGCTCAGCCGGATAGAGCGTCGGCCTCCGGAGCCGAAGGTCG
CAGGTTCGAATCCTGCCGGG

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MAGHAGDVFQPLALAVLTVSDTRGLAEDTSGAALAERLQGAGHVLAGRVIAPDDRYRIRAEVSAWIADSRVDGVLISGGT
GLTARDVTPEAVRPLLDREIPGFGELFRQRSFEEIGNATLQSRAVAGVANATLIFALPGSTGGCCTAWDRVLADQLDART
RPCNFATLLPRMRASEPLA

Sequences:

>Translated_179_residues
MAGHAGDVFQPLALAVLTVSDTRGLAEDTSGAALAERLQGAGHVLAGRVIAPDDRYRIRAEVSAWIADSRVDGVLISGGT
GLTARDVTPEAVRPLLDREIPGFGELFRQRSFEEIGNATLQSRAVAGVANATLIFALPGSTGGCCTAWDRVLADQLDART
RPCNFATLLPRMRASEPLA
>Mature_178_residues
AGHAGDVFQPLALAVLTVSDTRGLAEDTSGAALAERLQGAGHVLAGRVIAPDDRYRIRAEVSAWIADSRVDGVLISGGTG
LTARDVTPEAVRPLLDREIPGFGELFRQRSFEEIGNATLQSRAVAGVANATLIFALPGSTGGCCTAWDRVLADQLDARTR
PCNFATLLPRMRASEPLA

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=146, Percent_Identity=34.9315068493151, Blast_Score=81, Evalue=5e-16,
Organism=Homo sapiens, GI66932975, Length=146, Percent_Identity=34.9315068493151, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1787000, Length=163, Percent_Identity=60.7361963190184, Blast_Score=200, Evalue=4e-53,
Organism=Escherichia coli, GI1786190, Length=134, Percent_Identity=36.5671641791045, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=146, Percent_Identity=34.9315068493151, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17136978, Length=137, Percent_Identity=37.2262773722628, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24638841, Length=137, Percent_Identity=37.2262773722628, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18853; Mature: 18721

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGHAGDVFQPLALAVLTVSDTRGLAEDTSGAALAERLQGAGHVLAGRVIAPDDRYRIRA
CCCCCCHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHCCCCEEECCEECCCCCEEEEH
EVSAWIADSRVDGVLISGGTGLTARDVTPEAVRPLLDREIPGFGELFRQRSFEEIGNATL
HHHHHHHCCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
QSRAVAGVANATLIFALPGSTGGCCTAWDRVLADQLDARTRPCNFATLLPRMRASEPLA
HHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AGHAGDVFQPLALAVLTVSDTRGLAEDTSGAALAERLQGAGHVLAGRVIAPDDRYRIRA
CCCCCHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHCCCCEEECCEECCCCCEEEEH
EVSAWIADSRVDGVLISGGTGLTARDVTPEAVRPLLDREIPGFGELFRQRSFEEIGNATL
HHHHHHHCCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
QSRAVAGVANATLIFALPGSTGGCCTAWDRVLADQLDARTRPCNFATLLPRMRASEPLA
HHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]