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The map label for this gene is yggV [C]

Identifier: 121997763

GI number: 121997763

Start: 1044541

End: 1045140

Strand: Reverse

Name: yggV [C]

Synonym: Hhal_0972

Alternate gene names: 121997763

Gene position: 1045140-1044541 (Counterclockwise)

Preceding gene: 121997764

Following gene: 121997762

Centisome position: 39.02

GC content: 71.83

Gene sequence:

>600_bases
ATGAAGATCGTGCTGGCCACCGGGAATGCCGGCAAGCTTGCCGAGATGACCCGCATGCTCCAGGGCTACGACGCCGAGGT
GGTCAGGCAGGGGCACCTGGGCATCGACTCGCCCGCGGAGACCGGGCTGACCTTCGTCGAGAATGCGTTGATCAAGGCGC
GCCACTGCGCCGAGCGCAGCGGCCTGCCCGCGGTCGCCGACGACTCGGGGCTGGCCGTTCCGGCGCTCGGCGGCGAGCCC
GGCATCTACTCGGCGCGCTACGCCGGCAGCGATGCGGGCGACGCCGCCAACATCGAGCGCCTGCTCGCCGAGCTGAGCGA
GCGCGGGCAGGGCGACCGGCGCGGCACCTTCCACTGCGTTATGGTCTACCTGCGCCACGCCGCCGATCCGGCGCCGGTGA
TCGCCCACGGTAGCTGGACGGGGCGTATCGTCGAGACGCCGCGTGGCCATCACGGCTTCGGCTATGATCCGGTGTTCGAG
GATCCCGAACTCGGGCAGACCGCCGCCGAGCTGGATGCGCCCGCTAAGGACGCACGCAGCCACCGCGGGCAGGCGCTGCG
CGCGCTGATTCAGGGGATCGCCGCCGAGGTGGCCGGGTGA

Upstream 100 bases:

>100_bases
AGGGGCACGCCTTCCGGCGCGATGAACTCGATCGGATGCTGGCCCTGGCCGAGAAGGGCGTGGGTGAGCTGTTGCAGCAT
CAGCAGGAGGCATTGGCGAC

Downstream 100 bases:

>100_bases
CCCGGCGGCGCCCATGAGCCTCGGCGCCGGGGCGCAGCTGCCGCCGCTGGCGGTCTATATCCATCTGCCCTGGTGTCTGC
AGCGCTGCGGCTACTGCGAC

Product: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MKIVLATGNAGKLAEMTRMLQGYDAEVVRQGHLGIDSPAETGLTFVENALIKARHCAERSGLPAVADDSGLAVPALGGEP
GIYSARYAGSDAGDAANIERLLAELSERGQGDRRGTFHCVMVYLRHAADPAPVIAHGSWTGRIVETPRGHHGFGYDPVFE
DPELGQTAAELDAPAKDARSHRGQALRALIQGIAAEVAG

Sequences:

>Translated_199_residues
MKIVLATGNAGKLAEMTRMLQGYDAEVVRQGHLGIDSPAETGLTFVENALIKARHCAERSGLPAVADDSGLAVPALGGEP
GIYSARYAGSDAGDAANIERLLAELSERGQGDRRGTFHCVMVYLRHAADPAPVIAHGSWTGRIVETPRGHHGFGYDPVFE
DPELGQTAAELDAPAKDARSHRGQALRALIQGIAAEVAG
>Mature_199_residues
MKIVLATGNAGKLAEMTRMLQGYDAEVVRQGHLGIDSPAETGLTFVENALIKARHCAERSGLPAVADDSGLAVPALGGEP
GIYSARYAGSDAGDAANIERLLAELSERGQGDRRGTFHCVMVYLRHAADPAPVIAHGSWTGRIVETPRGHHGFGYDPVFE
DPELGQTAAELDAPAKDARSHRGQALRALIQGIAAEVAG

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=192, Percent_Identity=32.8125, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1789324, Length=192, Percent_Identity=55.2083333333333, Blast_Score=224, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17556833, Length=191, Percent_Identity=29.3193717277487, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_HALHL (A1WVN6)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002550.1
- ProteinModelPortal:   A1WVN6
- SMR:   A1WVN6
- STRING:   A1WVN6
- GeneID:   4709491
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_0972
- eggNOG:   COG0127
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- PhylomeDB:   A1WVN6
- BioCyc:   HHAL349124:HHAL_0972-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 20902; Mature: 20902

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVLATGNAGKLAEMTRMLQGYDAEVVRQGHLGIDSPAETGLTFVENALIKARHCAERS
CEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GLPAVADDSGLAVPALGGEPGIYSARYAGSDAGDAANIERLLAELSERGQGDRRGTFHCV
CCCCEECCCCCEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
MVYLRHAADPAPVIAHGSWTGRIVETPRGHHGFGYDPVFEDPELGQTAAELDAPAKDARS
HHHHHHCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHH
HRGQALRALIQGIAAEVAG
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIVLATGNAGKLAEMTRMLQGYDAEVVRQGHLGIDSPAETGLTFVENALIKARHCAERS
CEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GLPAVADDSGLAVPALGGEPGIYSARYAGSDAGDAANIERLLAELSERGQGDRRGTFHCV
CCCCEECCCCCEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
MVYLRHAADPAPVIAHGSWTGRIVETPRGHHGFGYDPVFEDPELGQTAAELDAPAKDARS
HHHHHHCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHH
HRGQALRALIQGIAAEVAG
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA