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The map label for this gene is argC

Identifier: 121997671

GI number: 121997671

Start: 958676

End: 959710

Strand: Reverse

Name: argC

Synonym: Hhal_0880

Alternate gene names: 121997671

Gene position: 959710-958676 (Counterclockwise)

Preceding gene: 121997673

Following gene: 121997670

Centisome position: 35.83

GC content: 71.3

Gene sequence:

>1035_bases
ATGATCGAAGTAGGCATAGTCGGCGGTACCGGATACACCGGTATGGAGCTGCTGCGCCTGGTGGCCCGCCACCCCAAGCT
GCGGTTGGCGGAGATTACCTCGCGGGCCGAGGCCGGGACGCGCGTCGACGAGCTGGTGCCGGCACTTGAGGGGGCCGTCG
ACAACGTCTTCACCGCCCCGGATACCGAGCGCCTGAGCCGGTGCGATGTGGTCTTCTTCGCCACGCCCAACGGCATCGCC
ATGGAGTCGGCGCCGGCGCTGCTCGAGGCCGGCTGCCGGGTCATCGATCTGGGGGCCGACTTCCGGCTGCGCGACCCGGC
GGTCTGGACCGAGTGGTACGGCATGAGTCACAGCTGCCCCGAGTTGCTTGAGGAGGCCGTCTACGGCCTGCCGGAGGCCA
ACCGCGATGCCCTGCCCGGGGCGCGACTGGTTGCCAACCCGGGCTGTTACCCCACCGCCGTGGCGCTGGGGCTGCTGCCG
TTGCTCGAGGCCGGGGCGCTGGCCGATGGGCCGGTGGTTGCCGATTGCAAGTCCGGGGTCTCCGGTGCCGGGCGGGCGGC
CAAGGTGGCCACGCTGTTCTGCGAGGCCAACGAGGGGTTCAAGGCCTACGGCGCCAGTGGCCATCGCCACCTGCCGGAGA
TCGAGCAGACCCTGGCCCGGGTGGCCGGCGCGCCGGTGGACGTGACCTTCGTCCCGCATCTGGTGCCCATGACCCGGGGT
ATGCAGGCCACCCTGCACGTCGTCGTGGACCGCCCGCTGGACGAGCTCGAGGCCCTCTACCGGCAGCGCTATGCCGACGA
GCCCTTCGTGCATCTGGTCGCCTCCGGGGGGCACCCCGAGACGCGCTGGGTGCGCGGGACCAACCACTGCCGGATCGGCC
TGCACCAGCCGCCGGGGCGTCCCGACCGGGCGGTGATCCTGTCGGTGATCGACAACCTCACCAAGGGCGCAGCCGGGCAG
GCGGTGCAGAACCTCAACCGGATGTTCGGCCTGGAGGAGACCGCCGGGCTCGAGGGGCTGGCCTACGTGCCGTAG

Upstream 100 bases:

>100_bases
GCTCGGTACTGACTCCGGGCGTATTGTAGGCCCAGCCAGTGTGCCGGCGGGAGTCCGTGCGGCCATCCGTAACCGGAAAC
AAGGGGGAGTGGAAAGACCC

Downstream 100 bases:

>100_bases
GTCGTCGTCGGTTTGACCTGGCCGGTAGGTGCCGACAGAATGCATGTTATCCGCCGTGGGCCAGGTCGGCCCCGGTGTCC
ATCTGCGGAGGGATAAGCCA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MIEVGIVGGTGYTGMELLRLVARHPKLRLAEITSRAEAGTRVDELVPALEGAVDNVFTAPDTERLSRCDVVFFATPNGIA
MESAPALLEAGCRVIDLGADFRLRDPAVWTEWYGMSHSCPELLEEAVYGLPEANRDALPGARLVANPGCYPTAVALGLLP
LLEAGALADGPVVADCKSGVSGAGRAAKVATLFCEANEGFKAYGASGHRHLPEIEQTLARVAGAPVDVTFVPHLVPMTRG
MQATLHVVVDRPLDELEALYRQRYADEPFVHLVASGGHPETRWVRGTNHCRIGLHQPPGRPDRAVILSVIDNLTKGAAGQ
AVQNLNRMFGLEETAGLEGLAYVP

Sequences:

>Translated_344_residues
MIEVGIVGGTGYTGMELLRLVARHPKLRLAEITSRAEAGTRVDELVPALEGAVDNVFTAPDTERLSRCDVVFFATPNGIA
MESAPALLEAGCRVIDLGADFRLRDPAVWTEWYGMSHSCPELLEEAVYGLPEANRDALPGARLVANPGCYPTAVALGLLP
LLEAGALADGPVVADCKSGVSGAGRAAKVATLFCEANEGFKAYGASGHRHLPEIEQTLARVAGAPVDVTFVPHLVPMTRG
MQATLHVVVDRPLDELEALYRQRYADEPFVHLVASGGHPETRWVRGTNHCRIGLHQPPGRPDRAVILSVIDNLTKGAAGQ
AVQNLNRMFGLEETAGLEGLAYVP
>Mature_344_residues
MIEVGIVGGTGYTGMELLRLVARHPKLRLAEITSRAEAGTRVDELVPALEGAVDNVFTAPDTERLSRCDVVFFATPNGIA
MESAPALLEAGCRVIDLGADFRLRDPAVWTEWYGMSHSCPELLEEAVYGLPEANRDALPGARLVANPGCYPTAVALGLLP
LLEAGALADGPVVADCKSGVSGAGRAAKVATLFCEANEGFKAYGASGHRHLPEIEQTLARVAGAPVDVTFVPHLVPMTRG
MQATLHVVVDRPLDELEALYRQRYADEPFVHLVASGGHPETRWVRGTNHCRIGLHQPPGRPDRAVILSVIDNLTKGAAGQ
AVQNLNRMFGLEETAGLEGLAYVP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=346, Percent_Identity=39.5953757225434, Blast_Score=202, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6320913, Length=343, Percent_Identity=30.0291545189504, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_HALHL (A1WVE4)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002458.1
- ProteinModelPortal:   A1WVE4
- SMR:   A1WVE4
- STRING:   A1WVE4
- GeneID:   4710267
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_0880
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- PhylomeDB:   A1WVE4
- BioCyc:   HHAL349124:HHAL_0880-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36678; Mature: 36678

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVGIVGGTGYTGMELLRLVARHPKLRLAEITSRAEAGTRVDELVPALEGAVDNVFTAP
CEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
DTERLSRCDVVFFATPNGIAMESAPALLEAGCRVIDLGADFRLRDPAVWTEWYGMSHSCP
CHHHHHHCCEEEEECCCCCCCCCCCHHHHCCCEEEECCCCCEECCCCHHHHHCCCCCCHH
ELLEEAVYGLPEANRDALPGARLVANPGCYPTAVALGLLPLLEAGALADGPVVADCKSGV
HHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEECHHCCC
SGAGRAAKVATLFCEANEGFKAYGASGHRHLPEIEQTLARVAGAPVDVTFVPHLVPMTRG
CCCCCHHEEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHCC
MQATLHVVVDRPLDELEALYRQRYADEPFVHLVASGGHPETRWVRGTNHCRIGLHQPPGR
CCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCEEEECCCCCCC
PDRAVILSVIDNLTKGAAGQAVQNLNRMFGLEETAGLEGLAYVP
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCEECCC
>Mature Secondary Structure
MIEVGIVGGTGYTGMELLRLVARHPKLRLAEITSRAEAGTRVDELVPALEGAVDNVFTAP
CEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
DTERLSRCDVVFFATPNGIAMESAPALLEAGCRVIDLGADFRLRDPAVWTEWYGMSHSCP
CHHHHHHCCEEEEECCCCCCCCCCCHHHHCCCEEEECCCCCEECCCCHHHHHCCCCCCHH
ELLEEAVYGLPEANRDALPGARLVANPGCYPTAVALGLLPLLEAGALADGPVVADCKSGV
HHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEECHHCCC
SGAGRAAKVATLFCEANEGFKAYGASGHRHLPEIEQTLARVAGAPVDVTFVPHLVPMTRG
CCCCCHHEEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHCC
MQATLHVVVDRPLDELEALYRQRYADEPFVHLVASGGHPETRWVRGTNHCRIGLHQPPGR
CCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCEEEECCCCCCC
PDRAVILSVIDNLTKGAAGQAVQNLNRMFGLEETAGLEGLAYVP
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA