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The map label for this gene is erpA

Identifier: 121997670

GI number: 121997670

Start: 958205

End: 958576

Strand: Reverse

Name: erpA

Synonym: Hhal_0879

Alternate gene names: 121997670

Gene position: 958576-958205 (Counterclockwise)

Preceding gene: 121997671

Following gene: 121997667

Centisome position: 35.79

GC content: 64.25

Gene sequence:

>372_bases
ATGAGCGATATCGCCGAGCCCGAGACCCACGCCCCGGCCGATGATCAGCTGCTGATCTTCACCGACGCCGCTGCGGACAA
GGTCCGCGAGCTGCTCGACGGCGAGGAGGGGGGCGACGTCAAGTTGCGCGTCTTCATCACCGGCGGTGGCTGTTCCGGTT
TCCAGTACGGCTTCACCTTCGACGAGACCGTCGAAGAGGGCGACACCATTATCGAGAAGCGCGGGGTCAAGATCGTCGTC
GATCCGGTCAGCGGCATCTACCTGCAGGGGGCTGAGGTCGACTTCTCCAGCGGTCTCGAGGGCGAGCAGTTCATCATCCG
CAATCCCAACGCCACCACCACCTGCGGCTGCGGCTCGTCCTTCGCCATCTAG

Upstream 100 bases:

>100_bases
GGTCGTCGTCGGTTTGACCTGGCCGGTAGGTGCCGACAGAATGCATGTTATCCGCCGTGGGCCAGGTCGGCCCCGGTGTC
CATCTGCGGAGGGATAAGCC

Downstream 100 bases:

>100_bases
GCGGCGCCCGAGGCGGGGTTACGGTGCGTAGACCCCGCCCAGGACCGCCCTGCGTCGGGCTCCGGTGACCGACGGCAGGT
TGCCGGGGTGGTGGTGCAGC

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MSDIAEPETHAPADDQLLIFTDAAADKVRELLDGEEGGDVKLRVFITGGGCSGFQYGFTFDETVEEGDTIIEKRGVKIVV
DPVSGIYLQGAEVDFSSGLEGEQFIIRNPNATTTCGCGSSFAI

Sequences:

>Translated_123_residues
MSDIAEPETHAPADDQLLIFTDAAADKVRELLDGEEGGDVKLRVFITGGGCSGFQYGFTFDETVEEGDTIIEKRGVKIVV
DPVSGIYLQGAEVDFSSGLEGEQFIIRNPNATTTCGCGSSFAI
>Mature_122_residues
SDIAEPETHAPADDQLLIFTDAAADKVRELLDGEEGGDVKLRVFITGGGCSGFQYGFTFDETVEEGDTIIEKRGVKIVVD
PVSGIYLQGAEVDFSSGLEGEQFIIRNPNATTTCGCGSSFAI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=105, Percent_Identity=40.9523809523809, Blast_Score=84, Evalue=3e-17,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=30.188679245283, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=65.0943396226415, Blast_Score=146, Evalue=5e-37,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=35.8490566037736, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1787974, Length=108, Percent_Identity=34.2592592592593, Blast_Score=61, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71998452, Length=125, Percent_Identity=36.8, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=31.1320754716981, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=31.1320754716981, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=107, Percent_Identity=32.7102803738318, Blast_Score=65, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=32.0754716981132, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_HALHL (A1WVE3)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002457.1
- ProteinModelPortal:   A1WVE3
- SMR:   A1WVE3
- STRING:   A1WVE3
- GeneID:   4710266
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_0879
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- PhylomeDB:   A1WVE3
- ProtClustDB:   PRK13623
- BioCyc:   HHAL349124:HHAL_0879-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13070; Mature: 12938

Theoretical pI: Translated: 3.84; Mature: 3.84

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIAEPETHAPADDQLLIFTDAAADKVRELLDGEEGGDVKLRVFITGGGCSGFQYGFTF
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCC
DETVEEGDTIIEKRGVKIVVDPVSGIYLQGAEVDFSSGLEGEQFIIRNPNATTTCGCGSS
HHHHHCCCCEEECCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCCEEECCCCC
FAI
CCC
>Mature Secondary Structure 
SDIAEPETHAPADDQLLIFTDAAADKVRELLDGEEGGDVKLRVFITGGGCSGFQYGFTF
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCC
DETVEEGDTIIEKRGVKIVVDPVSGIYLQGAEVDFSSGLEGEQFIIRNPNATTTCGCGSS
HHHHHCCCCEEECCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCCEEECCCCC
FAI
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA