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The map label for this gene is yfjP [H]

Identifier: 121611835

GI number: 121611835

Start: 5456924

End: 5457628

Strand: Direct

Name: yfjP [H]

Synonym: Veis_4937

Alternate gene names: 121611835

Gene position: 5456924-5457628 (Clockwise)

Preceding gene: 121611834

Following gene: 121611836

Centisome position: 98.03

GC content: 63.55

Gene sequence:

>705_bases
ATGGCGGCTGCTAAGAAAACGACCTCTGCGGCGGCGCAGGCCGGCACGGAGGCCAGCCCCGGCGTCCACCCCGATATCCG
CCCCGATGCCCGCCCCGGCTATTGGGCCGAAGCCTGCAAGCAGTTGATGAAAAAGGATCGGGTGATGAAGCGCCTGATCC
CCCAGTCCGGCAACGCCACATTGCAAACCCGGGGCGATGCGTTCACCACGCTGGCGCGCAGCATCGTCGGGCAGCAGATT
TCGGTGAAGGCGGCGCAAACCGTGTGGGAGCGCTTCGCCCTGCTGCCTTGCAGCATGAAGCCGGCCAACGTGCTCAAGCT
CAGGATCGACGACATGCGTGCTGCCGGCCTGTCGGCCCGCAAGGTCGACTATCTGGTCGACCTGTCGATGCACTTCGAGA
GCGGCCAGTTGCATGTGAAGGACTGGGCGGCGATGGACGACGAAGCCATCATTGCCGAACTGATCGCGATTCGCGGCATT
GGCCGCTGGACGGCCGAGATGTTCCTGATCTTCTACCTGATGCGGCCCAACGTATTGCCGCTGGACGACCTGGGGCTGAT
CAATGGCATCAGCCTGAATTACTTTTCCGGCGACCCCGTCAGCCGCAGCGATGCCCGTGAAGTGGCCCAGGCCTGGAAGC
CTTGGTGCAGCGTGGCGACTTGGTATATTTGGCGCTCGCTGGACCCGCTGCCGGTGGTGTATTGA

Upstream 100 bases:

>100_bases
CATCGTGCTCAAGGACGGCGCGACAGGAACCACATGGGAAGCCGCGCAGTGATCTTTGCCCTGTTTGCGGCCAACGCCCC
CGGGGCGAAGGGAGCGCCCG

Downstream 100 bases:

>100_bases
CGCCATGGTCGGCCCTAGTGTCGCGTCACCGATCATCTGTCGGTCTGCGCCGGCCATCGAAGCGCAGCCTACGACATCTG
ATCGGTGACGCGACACTAGC

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAAAKKTTSAAAQAGTEASPGVHPDIRPDARPGYWAEACKQLMKKDRVMKRLIPQSGNATLQTRGDAFTTLARSIVGQQI
SVKAAQTVWERFALLPCSMKPANVLKLRIDDMRAAGLSARKVDYLVDLSMHFESGQLHVKDWAAMDDEAIIAELIAIRGI
GRWTAEMFLIFYLMRPNVLPLDDLGLINGISLNYFSGDPVSRSDAREVAQAWKPWCSVATWYIWRSLDPLPVVY

Sequences:

>Translated_234_residues
MAAAKKTTSAAAQAGTEASPGVHPDIRPDARPGYWAEACKQLMKKDRVMKRLIPQSGNATLQTRGDAFTTLARSIVGQQI
SVKAAQTVWERFALLPCSMKPANVLKLRIDDMRAAGLSARKVDYLVDLSMHFESGQLHVKDWAAMDDEAIIAELIAIRGI
GRWTAEMFLIFYLMRPNVLPLDDLGLINGISLNYFSGDPVSRSDAREVAQAWKPWCSVATWYIWRSLDPLPVVY
>Mature_233_residues
AAAKKTTSAAAQAGTEASPGVHPDIRPDARPGYWAEACKQLMKKDRVMKRLIPQSGNATLQTRGDAFTTLARSIVGQQIS
VKAAQTVWERFALLPCSMKPANVLKLRIDDMRAAGLSARKVDYLVDLSMHFESGQLHVKDWAAMDDEAIIAELIAIRGIG
RWTAEMFLIFYLMRPNVLPLDDLGLINGISLNYFSGDPVSRSDAREVAQAWKPWCSVATWYIWRSLDPLPVVY

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 25992; Mature: 25861

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAKKTTSAAAQAGTEASPGVHPDIRPDARPGYWAEACKQLMKKDRVMKRLIPQSGNAT
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
LQTRGDAFTTLARSIVGQQISVKAAQTVWERFALLPCSMKPANVLKLRIDDMRAAGLSAR
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCHH
KVDYLVDLSMHFESGQLHVKDWAAMDDEAIIAELIAIRGIGRWTAEMFLIFYLMRPNVLP
HHHEEEEEEEECCCCEEEEHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
LDDLGLINGISLNYFSGDPVSRSDAREVAQAWKPWCSVATWYIWRSLDPLPVVY
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AAAKKTTSAAAQAGTEASPGVHPDIRPDARPGYWAEACKQLMKKDRVMKRLIPQSGNAT
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
LQTRGDAFTTLARSIVGQQISVKAAQTVWERFALLPCSMKPANVLKLRIDDMRAAGLSAR
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCHH
KVDYLVDLSMHFESGQLHVKDWAAMDDEAIIAELIAIRGIGRWTAEMFLIFYLMRPNVLP
HHHEEEEEEEECCCCEEEEHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
LDDLGLINGISLNYFSGDPVSRSDAREVAQAWKPWCSVATWYIWRSLDPLPVVY
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]