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The map label for this gene is potC [H]

Identifier: 121611659

GI number: 121611659

Start: 5245296

End: 5246090

Strand: Direct

Name: potC [H]

Synonym: Veis_4754

Alternate gene names: 121611659

Gene position: 5245296-5246090 (Clockwise)

Preceding gene: 121611658

Following gene: 121611660

Centisome position: 94.23

GC content: 61.89

Gene sequence:

>795_bases
ATGACCCACCGCAACACCGCGCTGTGGCGCTTTCCCGGGCTGGGATTGAACTTCGGCATCGCATTGGTCTTTTTGTACCT
GCCGATCGTGCTGCTGGTGCTGCTGTCGTTCAATGAAAACAACGTGGCCACCCTGTGGACCGGTTTGTCCCTGCGCTGGT
ACGGCATTGTCTTTGACAACCCGAACATCCTGCGGGCGGCCGGAAACTCGATGCTGGTGGCATGTGTCGCCACCGTCGTC
TCCACGGTCTTCGCCGGCATGGCCGCGCTGGCCATGGCGCGCCGGAATTTCAAGGGCCAGAACGTGATCAGCGGCATGTT
GGGGCTGCCGTTGCTGGTGCCGGAAATCGTCACTGCCGTGGCATCGCTGCTGTTTTTTCTGTCCTTGGGCATGGATTTGG
GGCTGCGCACGGTGACGATAGCGCACATCGTGTTTTGCATTCCGTTCGCTTACCTGCCGATACGGGCGCGGCTGGCGAAC
ATGGACCCGCGGCTGGTCGAGGCGGCGGCAGATCTGTACGCATCCCCCGGGCAGGCATTCCGCCGGATCACCCTGCCCTT
GTTGATGCCGGGCATCATCAGCGGCGCGATGCTGGCATTCATCGTGTCGCTGGATGACTTCGTCATCACCTTCTTTGTCG
CCGGCCCCGGCGCCACCACATTGCCGGTCTACATCTTTGGCATGGTGCGCATGGGGATCACGCCGGAAGTCAACGCCCTG
GCGGCCTTGCTGCTGATCGCATCCATGGTGTTTGTCGGTCTTTCGTGGTGGATTGGCCAGCGCGACCGCCGTTGA

Upstream 100 bases:

>100_bases
GCAATTGGCCCTTCGGTTCGGCACTGGCTTTCGCATTGCTTTCGATCGTGCTGGCAGGCATGTTGCTGTATACGCGCCGG
TTCAAAAAGGCTCTGGACAC

Downstream 100 bases:

>100_bases
TTTTTGATCCGATGGAGATGAAGATGCTTGGGAAAATCGTGACCAAACTGGCCGCCCTGGCCATGACAGCCGGTATTTTG
CTCTCCGGAGCAGCGCATGC

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTHRNTALWRFPGLGLNFGIALVFLYLPIVLLVLLSFNENNVATLWTGLSLRWYGIVFDNPNILRAAGNSMLVACVATVV
STVFAGMAALAMARRNFKGQNVISGMLGLPLLVPEIVTAVASLLFFLSLGMDLGLRTVTIAHIVFCIPFAYLPIRARLAN
MDPRLVEAAADLYASPGQAFRRITLPLLMPGIISGAMLAFIVSLDDFVITFFVAGPGATTLPVYIFGMVRMGITPEVNAL
AALLLIASMVFVGLSWWIGQRDRR

Sequences:

>Translated_264_residues
MTHRNTALWRFPGLGLNFGIALVFLYLPIVLLVLLSFNENNVATLWTGLSLRWYGIVFDNPNILRAAGNSMLVACVATVV
STVFAGMAALAMARRNFKGQNVISGMLGLPLLVPEIVTAVASLLFFLSLGMDLGLRTVTIAHIVFCIPFAYLPIRARLAN
MDPRLVEAAADLYASPGQAFRRITLPLLMPGIISGAMLAFIVSLDDFVITFFVAGPGATTLPVYIFGMVRMGITPEVNAL
AALLLIASMVFVGLSWWIGQRDRR
>Mature_263_residues
THRNTALWRFPGLGLNFGIALVFLYLPIVLLVLLSFNENNVATLWTGLSLRWYGIVFDNPNILRAAGNSMLVACVATVVS
TVFAGMAALAMARRNFKGQNVISGMLGLPLLVPEIVTAVASLLFFLSLGMDLGLRTVTIAHIVFCIPFAYLPIRARLANM
DPRLVEAAADLYASPGQAFRRITLPLLMPGIISGAMLAFIVSLDDFVITFFVAGPGATTLPVYIFGMVRMGITPEVNALA
ALLLIASMVFVGLSWWIGQRDRR

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=228, Percent_Identity=39.4736842105263, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1787081, Length=263, Percent_Identity=40.3041825095057, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1787714, Length=243, Percent_Identity=34.156378600823, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788764, Length=174, Percent_Identity=28.1609195402299, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787713, Length=71, Percent_Identity=43.6619718309859, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28662; Mature: 28531

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHRNTALWRFPGLGLNFGIALVFLYLPIVLLVLLSFNENNVATLWTGLSLRWYGIVFDN
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEEEECC
PNILRAAGNSMLVACVATVVSTVFAGMAALAMARRNFKGQNVISGMLGLPLLVPEIVTAV
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ASLLFFLSLGMDLGLRTVTIAHIVFCIPFAYLPIRARLANMDPRLVEAAADLYASPGQAF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
RRITLPLLMPGIISGAMLAFIVSLDDFVITFFVAGPGATTLPVYIFGMVRMGITPEVNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCCHHHH
AALLLIASMVFVGLSWWIGQRDRR
HHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
THRNTALWRFPGLGLNFGIALVFLYLPIVLLVLLSFNENNVATLWTGLSLRWYGIVFDN
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEEEECC
PNILRAAGNSMLVACVATVVSTVFAGMAALAMARRNFKGQNVISGMLGLPLLVPEIVTAV
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ASLLFFLSLGMDLGLRTVTIAHIVFCIPFAYLPIRARLANMDPRLVEAAADLYASPGQAF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
RRITLPLLMPGIISGAMLAFIVSLDDFVITFFVAGPGATTLPVYIFGMVRMGITPEVNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCCHHHH
AALLLIASMVFVGLSWWIGQRDRR
HHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]