Click here to switch to the map view.

The map label for this gene is gsiD [H]

Identifier: 121611502

GI number: 121611502

Start: 5087558

End: 5088484

Strand: Direct

Name: gsiD [H]

Synonym: Veis_4593

Alternate gene names: 121611502

Gene position: 5087558-5088484 (Clockwise)

Preceding gene: 121611501

Following gene: 121611503

Centisome position: 91.39

GC content: 66.77

Gene sequence:

>927_bases
ATGACGCAAGATTCCGGCGTGCCTGCCGAATCCATCGTTCCTCTTTCTCCTGTCGCCGTGGGGCAAACCGCGGGCAAGGT
CCGCACGCCCTGGGGCGAATGCTGGCGCCGCTTCAAGAAGCAGCCCGTGGGCATCGTGGCAGCCATCTTCGTGGGGCTGC
TGGTGTGCATCGCGGTGATCGCACCATGGATCGCGCCCTTCGACCCCGAGAACTTCTTCGACTACGACACGCTGAACAGC
GGGCCTTCGGCCACGCACTGGTTCGGCGTCGATCCGCTGGGCCGCGACATCTTCAGCCGCATCCTGGCGGGCACGCGCAT
CTCGCTGGCAGCCGGCTTTTTGTCGGTGCTGGTGGGCGGCATCATCGGCACGGCCTTCGGCCTGCTGGCGGGCTACTACG
AAGGCTGGTGGGACCGCATCGTGATGCGCATCTCGGACGTGCTGTTCGCCTTCCCCGGCATCCTGCTGGCGCTGGGCGTG
GTGGCCATCCTGGGCAGCAGCATGACCAACGTGGTGGTGGCGGTGGCGGTGTTCAGCGTGCCGGCCTTTGCGCGCCTGGT
GCGCGGCAACACGCTGGTGCTCAAGCAGCAGACCTACATCGAGGCCGAGCGCAGCATCGGCGCGTCCGACTGGACCATCA
TCGTGCGGCACATCCTGCCGGGCACGATCTCGTCGATCGTCGTGTACTTCTCGATGCGCGTGGGCACCTCGATCATCACG
GCGGCCAGCCTGTCGTTTCTGGGCATGGGCGCACAGCCGCCGACGCCCGAGTGGGGCGCGATGCTCAACGAAGCCCGTGC
CGACATGGTGACCTCGCCGCACGTGGCGCTGTTCCCGAGCCTGGCCATCTTCTTGACCGTGCTGGCCTTCAACCTGCTGG
GCGACGCCCTGCGCGACGCGCTCGATCCGAAGATCGAGCGCCAGTAA

Upstream 100 bases:

>100_bases
GTGCTGCTGTTCTCGCTCGAATTCATCCTGATCAACCTCGTGGTCGATGTGCTGTACGGCCTCATCAACCCGACCATCCG
CTACAAGTGAGCACGCAGCC

Downstream 100 bases:

>100_bases
GTTCTTCGTTCTTCTTTCTCGCTTCATGGCCTCGACGACCTCCCTGCCCTTCATCGGCACCCTCCCTGCGGGCACGCGCG
ACGCCATCACCGACGTCGCG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTQDSGVPAESIVPLSPVAVGQTAGKVRTPWGECWRRFKKQPVGIVAAIFVGLLVCIAVIAPWIAPFDPENFFDYDTLNS
GPSATHWFGVDPLGRDIFSRILAGTRISLAAGFLSVLVGGIIGTAFGLLAGYYEGWWDRIVMRISDVLFAFPGILLALGV
VAILGSSMTNVVVAVAVFSVPAFARLVRGNTLVLKQQTYIEAERSIGASDWTIIVRHILPGTISSIVVYFSMRVGTSIIT
AASLSFLGMGAQPPTPEWGAMLNEARADMVTSPHVALFPSLAIFLTVLAFNLLGDALRDALDPKIERQ

Sequences:

>Translated_308_residues
MTQDSGVPAESIVPLSPVAVGQTAGKVRTPWGECWRRFKKQPVGIVAAIFVGLLVCIAVIAPWIAPFDPENFFDYDTLNS
GPSATHWFGVDPLGRDIFSRILAGTRISLAAGFLSVLVGGIIGTAFGLLAGYYEGWWDRIVMRISDVLFAFPGILLALGV
VAILGSSMTNVVVAVAVFSVPAFARLVRGNTLVLKQQTYIEAERSIGASDWTIIVRHILPGTISSIVVYFSMRVGTSIIT
AASLSFLGMGAQPPTPEWGAMLNEARADMVTSPHVALFPSLAIFLTVLAFNLLGDALRDALDPKIERQ
>Mature_307_residues
TQDSGVPAESIVPLSPVAVGQTAGKVRTPWGECWRRFKKQPVGIVAAIFVGLLVCIAVIAPWIAPFDPENFFDYDTLNSG
PSATHWFGVDPLGRDIFSRILAGTRISLAAGFLSVLVGGIIGTAFGLLAGYYEGWWDRIVMRISDVLFAFPGILLALGVV
AILGSSMTNVVVAVAVFSVPAFARLVRGNTLVLKQQTYIEAERSIGASDWTIIVRHILPGTISSIVVYFSMRVGTSIITA
ASLSFLGMGAQPPTPEWGAMLNEARADMVTSPHVALFPSLAIFLTVLAFNLLGDALRDALDPKIERQ

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=281, Percent_Identity=74.7330960854093, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1787760, Length=267, Percent_Identity=40.4494382022472, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1789964, Length=284, Percent_Identity=41.9014084507042, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=39.1836734693878, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787498, Length=279, Percent_Identity=36.9175627240143, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787549, Length=287, Percent_Identity=31.0104529616725, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788505, Length=236, Percent_Identity=31.7796610169492, Blast_Score=114, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33005; Mature: 32874

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDSGVPAESIVPLSPVAVGQTAGKVRTPWGECWRRFKKQPVGIVAAIFVGLLVCIAVI
CCCCCCCCHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
APWIAPFDPENFFDYDTLNSGPSATHWFGVDPLGRDIFSRILAGTRISLAAGFLSVLVGG
HHHCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IIGTAFGLLAGYYEGWWDRIVMRISDVLFAFPGILLALGVVAILGSSMTNVVVAVAVFSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
PAFARLVRGNTLVLKQQTYIEAERSIGASDWTIIVRHILPGTISSIVVYFSMRVGTSIIT
HHHHHHHCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AASLSFLGMGAQPPTPEWGAMLNEARADMVTSPHVALFPSLAIFLTVLAFNLLGDALRDA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDPKIERQ
CCCCCCCC
>Mature Secondary Structure 
TQDSGVPAESIVPLSPVAVGQTAGKVRTPWGECWRRFKKQPVGIVAAIFVGLLVCIAVI
CCCCCCCHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
APWIAPFDPENFFDYDTLNSGPSATHWFGVDPLGRDIFSRILAGTRISLAAGFLSVLVGG
HHHCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IIGTAFGLLAGYYEGWWDRIVMRISDVLFAFPGILLALGVVAILGSSMTNVVVAVAVFSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
PAFARLVRGNTLVLKQQTYIEAERSIGASDWTIIVRHILPGTISSIVVYFSMRVGTSIIT
HHHHHHHCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AASLSFLGMGAQPPTPEWGAMLNEARADMVTSPHVALFPSLAIFLTVLAFNLLGDALRDA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDPKIERQ
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]