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The map label for this gene is mtnN [H]

Identifier: 121611340

GI number: 121611340

Start: 4875933

End: 4876904

Strand: Direct

Name: mtnN [H]

Synonym: Veis_4426

Alternate gene names: 121611340

Gene position: 4875933-4876904 (Clockwise)

Preceding gene: 121611339

Following gene: 121611341

Centisome position: 87.59

GC content: 67.8

Gene sequence:

>972_bases
ATGCACCACACCGCGCACGCGCCACGCCCTGGCCTGATCCAACGCAGCATCCGCCGGCTGGGCCTGTGGGCGCTGGCCAT
GCTCGTCACCGGCTGCGCGTCGGTGCCGCCCGACAAGCAGGCGCTGCGGCTCGATGACCAGCCGCGCATCGCCGTGATCT
CGGCCTTTGCGCCCGAACTCGCGCTGCTGCTGGCGCAGTTGCAGCAGCCGGTGTCGCACCGCATCGGCGGCGTGGAGTTC
AGCACCGGCCTGTTGGCCGGCAAGCCGGTGGTGCTGTTCCTGTCGGGCATAAGCATGACCAATGCGGCGATGAACACGCA
GCGGGTGCTGGACCGCTTCGACATCAGCCACATCATGTTCAGCGGCATCGCCGGCGGCGTGAACCCCGGCCTGCATATCG
GCGATGTCAGCGTGCCGGCGCAGTGGGGCCAGTACATGGAATGGCTGATGGCCCGCGAAGGCCCGCCCGGCCAGTACAGC
GTGCCGGAATGGATGAAAAGCGAACTGCTGCCCCTGCCGGCCTTCGGCATGATGCACCCGCGTTCGGTGCAAGTGCGCTC
GGCCGCCAGCCCGCAGATCAGCCAACAGTTCTGGTTTGCCGCCGATGCCCGGATGCTGGCGCTGGCGCGCAGCCTGCAAG
ACATCGATCTGGCGCATTGCCACGCCGGCCAATGCCTGCAACGGCGCCCGCGCGTGGTGGTGGGCGGCAACGGCGTATCC
GGCCCGGCCTTCGTGGACAACAAGGCGTTTCGCGAATACACGTTCAACACCTTCGAGGCCCAGGTGCTGGACATGGAAAC
CGCCGCCACCGCGATGGTCGCGCATGGCAACGGCGTGCCTTTCATCGCCTTCCGCTCGCTCAGCGATCTGGCCGGCGGCG
GCGCGGGCGACAACGAGATGGCGACCTTCATGCAGTTGGCCGCAGCCAATTCGGCCAAGGTGCTGCTGGCCTTTCTCGCC
GCCTGGCAATGA

Upstream 100 bases:

>100_bases
AGGCGGATATCCTGGCCGGCCGGTTTACCGTGAAGATCGACGACAGCCAACCCCAATCCACGGCCGCGACAGCCGCCAAA
TAAAAGCAAGGAACCCGGCC

Downstream 100 bases:

>100_bases
CGGCGCCGGGCGCTCCCGTGCTGCGCCTGTGCGGCATCAGCAAGCGCTTTGGCCCGCTGCTGGCCAATGACGACATCAGC
CTGGACTTGCAGCGCGGCCA

Product: methylthioadenosine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MHHTAHAPRPGLIQRSIRRLGLWALAMLVTGCASVPPDKQALRLDDQPRIAVISAFAPELALLLAQLQQPVSHRIGGVEF
STGLLAGKPVVLFLSGISMTNAAMNTQRVLDRFDISHIMFSGIAGGVNPGLHIGDVSVPAQWGQYMEWLMAREGPPGQYS
VPEWMKSELLPLPAFGMMHPRSVQVRSAASPQISQQFWFAADARMLALARSLQDIDLAHCHAGQCLQRRPRVVVGGNGVS
GPAFVDNKAFREYTFNTFEAQVLDMETAATAMVAHGNGVPFIAFRSLSDLAGGGAGDNEMATFMQLAAANSAKVLLAFLA
AWQ

Sequences:

>Translated_323_residues
MHHTAHAPRPGLIQRSIRRLGLWALAMLVTGCASVPPDKQALRLDDQPRIAVISAFAPELALLLAQLQQPVSHRIGGVEF
STGLLAGKPVVLFLSGISMTNAAMNTQRVLDRFDISHIMFSGIAGGVNPGLHIGDVSVPAQWGQYMEWLMAREGPPGQYS
VPEWMKSELLPLPAFGMMHPRSVQVRSAASPQISQQFWFAADARMLALARSLQDIDLAHCHAGQCLQRRPRVVVGGNGVS
GPAFVDNKAFREYTFNTFEAQVLDMETAATAMVAHGNGVPFIAFRSLSDLAGGGAGDNEMATFMQLAAANSAKVLLAFLA
AWQ
>Mature_323_residues
MHHTAHAPRPGLIQRSIRRLGLWALAMLVTGCASVPPDKQALRLDDQPRIAVISAFAPELALLLAQLQQPVSHRIGGVEF
STGLLAGKPVVLFLSGISMTNAAMNTQRVLDRFDISHIMFSGIAGGVNPGLHIGDVSVPAQWGQYMEWLMAREGPPGQYS
VPEWMKSELLPLPAFGMMHPRSVQVRSAASPQISQQFWFAADARMLALARSLQDIDLAHCHAGQCLQRRPRVVVGGNGVS
GPAFVDNKAFREYTFNTFEAQVLDMETAATAMVAHGNGVPFIAFRSLSDLAGGGAGDNEMATFMQLAAANSAKVLLAFLA
AWQ

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 34791; Mature: 34791

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHTAHAPRPGLIQRSIRRLGLWALAMLVTGCASVPPDKQALRLDDQPRIAVISAFAPEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEEHHHHHH
ALLLAQLQQPVSHRIGGVEFSTGLLAGKPVVLFLSGISMTNAAMNTQRVLDRFDISHIMF
HHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
SGIAGGVNPGLHIGDVSVPAQWGQYMEWLMAREGPPGQYSVPEWMKSELLPLPAFGMMHP
HHHCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
RSVQVRSAASPQISQQFWFAADARMLALARSLQDIDLAHCHAGQCLQRRPRVVVGGNGVS
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHCCCEEECCCCCC
GPAFVDNKAFREYTFNTFEAQVLDMETAATAMVAHGNGVPFIAFRSLSDLAGGGAGDNEM
CCCEECCHHHHHHCCCCHHHHEEEHHHHHHEEEECCCCCCEEEECCHHHHCCCCCCCHHH
ATFMQLAAANSAKVLLAFLAAWQ
HHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MHHTAHAPRPGLIQRSIRRLGLWALAMLVTGCASVPPDKQALRLDDQPRIAVISAFAPEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEEHHHHHH
ALLLAQLQQPVSHRIGGVEFSTGLLAGKPVVLFLSGISMTNAAMNTQRVLDRFDISHIMF
HHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
SGIAGGVNPGLHIGDVSVPAQWGQYMEWLMAREGPPGQYSVPEWMKSELLPLPAFGMMHP
HHHCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
RSVQVRSAASPQISQQFWFAADARMLALARSLQDIDLAHCHAGQCLQRRPRVVVGGNGVS
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHCCCEEECCCCCC
GPAFVDNKAFREYTFNTFEAQVLDMETAATAMVAHGNGVPFIAFRSLSDLAGGGAGDNEM
CCCEECCHHHHHHCCCCHHHHEEEHHHHHHEEEECCCCCCEEEECCHHHHCCCCCCCHHH
ATFMQLAAANSAKVLLAFLAAWQ
HHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA