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The map label for this gene is motA [H]

Identifier: 121611335

GI number: 121611335

Start: 4871810

End: 4872670

Strand: Direct

Name: motA [H]

Synonym: Veis_4421

Alternate gene names: 121611335

Gene position: 4871810-4872670 (Clockwise)

Preceding gene: 121611321

Following gene: 121611336

Centisome position: 87.52

GC content: 62.83

Gene sequence:

>861_bases
ATGTACGTCTGCATCGGCTACCTCCTCTGCCTGGGCTGCATCTTCGGCGCGTACATCTTGCATGGCGGCAATATCGGCGT
GATCCTGAAGGCCTTGCCATACGAGCTCGTCATCATTGGCGGCGGCGCCCTGGGCGCCTTCGTGGTGAACAACCAGGGCA
AGGTGATCAAGGCCACGCTGCGGGCGATACCGAGTGCGTTCCCTGCGTCCAGATACACCAAGGAGCGCTACATGGAACTG
ATGGCAATGCTCCATGAGTTGCTGCAAAAAATCCGCCGGGAGGGGCTGCTGAAGATCGAAAAGGATGTCGACGATCCCCA
GGGATCGCCGATCTTCAGCAAATACCCCACGGTGGGCCGCGACCCGCGTGTGATCGAGTTCATGACCGACTACCTGCGCA
TGATGGTCTCGGGCAACCTGAACGCGCACGAAATCGAGGCCCTGATGGACAGCGAAATCGACACCTACCACCAGGAATCC
CATGCCCCGGTGGCGGCGCTGGCCCGGCTGGCCGGCGCCTTGCCCGCGTTCGGCATCGTCGCCGCCGTGCTCGGCGTGGT
CAACACCATGAGCGCCATGGGCCAGCCGCCGGCGGTGCTCGGCGCGATGATCGGCTCGGCGCTGCTCGGCACCTTCCTGG
GCATCTTGCTCGCCTATGGCGTGGTCGAGCCGTTTGGCGGTCTGCTCGAGCAAAGGGCCGACGATGCCGGCAAAGAGCTG
CAATGCATCAAGTCCACGCTGCTGGCCAGCATGCAGGGCTACAACCCGGCCACGGCCATAGAGTTCGGCCGCAAGGTGCT
TTTCAGCAGCGTGCGCCCGGGCTTTCTGGAACTGGAAAAGCATGTGAAGGAGCGCAAATGA

Upstream 100 bases:

>100_bases
TGTCGCGGCCTTGGGCGCCTGGCGATCCCGATACAGTCATTTCAAGGTCGAGCGCATTGACCACTGGCCTGCCCTCCTTC
GTTTTTGCTGCCTGCCCCAC

Downstream 100 bases:

>100_bases
CTGCGCCGGTTGCCGTCACGGCAGAAAAGAAACTCCAGCCCATCATCGTCCGGCGCGTGCACAGGGCCGCGCCTGCCGGG
CATATGGGCACCTGGAAAAT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MYVCIGYLLCLGCIFGAYILHGGNIGVILKALPYELVIIGGGALGAFVVNNQGKVIKATLRAIPSAFPASRYTKERYMEL
MAMLHELLQKIRREGLLKIEKDVDDPQGSPIFSKYPTVGRDPRVIEFMTDYLRMMVSGNLNAHEIEALMDSEIDTYHQES
HAPVAALARLAGALPAFGIVAAVLGVVNTMSAMGQPPAVLGAMIGSALLGTFLGILLAYGVVEPFGGLLEQRADDAGKEL
QCIKSTLLASMQGYNPATAIEFGRKVLFSSVRPGFLELEKHVKERK

Sequences:

>Translated_286_residues
MYVCIGYLLCLGCIFGAYILHGGNIGVILKALPYELVIIGGGALGAFVVNNQGKVIKATLRAIPSAFPASRYTKERYMEL
MAMLHELLQKIRREGLLKIEKDVDDPQGSPIFSKYPTVGRDPRVIEFMTDYLRMMVSGNLNAHEIEALMDSEIDTYHQES
HAPVAALARLAGALPAFGIVAAVLGVVNTMSAMGQPPAVLGAMIGSALLGTFLGILLAYGVVEPFGGLLEQRADDAGKEL
QCIKSTLLASMQGYNPATAIEFGRKVLFSSVRPGFLELEKHVKERK
>Mature_286_residues
MYVCIGYLLCLGCIFGAYILHGGNIGVILKALPYELVIIGGGALGAFVVNNQGKVIKATLRAIPSAFPASRYTKERYMEL
MAMLHELLQKIRREGLLKIEKDVDDPQGSPIFSKYPTVGRDPRVIEFMTDYLRMMVSGNLNAHEIEALMDSEIDTYHQES
HAPVAALARLAGALPAFGIVAAVLGVVNTMSAMGQPPAVLGAMIGSALLGTFLGILLAYGVVEPFGGLLEQRADDAGKEL
QCIKSTLLASMQGYNPATAIEFGRKVLFSSVRPGFLELEKHVKERK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=286, Percent_Identity=48.2517482517483, Blast_Score=300, Evalue=5e-83,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30915; Mature: 30915

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVCIGYLLCLGCIFGAYILHGGNIGVILKALPYELVIIGGGALGAFVVNNQGKVIKATL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCEEEEEECCCCCHHHHHH
RAIPSAFPASRYTKERYMELMAMLHELLQKIRREGLLKIEKDVDDPQGSPIFSKYPTVGR
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCCCCCCCCCC
DPRVIEFMTDYLRMMVSGNLNAHEIEALMDSEIDTYHQESHAPVAALARLAGALPAFGIV
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
AAVLGVVNTMSAMGQPPAVLGAMIGSALLGTFLGILLAYGVVEPFGGLLEQRADDAGKEL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QCIKSTLLASMQGYNPATAIEFGRKVLFSSVRPGFLELEKHVKERK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MYVCIGYLLCLGCIFGAYILHGGNIGVILKALPYELVIIGGGALGAFVVNNQGKVIKATL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCEEEEEECCCCCHHHHHH
RAIPSAFPASRYTKERYMELMAMLHELLQKIRREGLLKIEKDVDDPQGSPIFSKYPTVGR
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCCCCCCCCCC
DPRVIEFMTDYLRMMVSGNLNAHEIEALMDSEIDTYHQESHAPVAALARLAGALPAFGIV
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
AAVLGVVNTMSAMGQPPAVLGAMIGSALLGTFLGILLAYGVVEPFGGLLEQRADDAGKEL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QCIKSTLLASMQGYNPATAIEFGRKVLFSSVRPGFLELEKHVKERK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]