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The map label for this gene is amaB [H]

Identifier: 121611303

GI number: 121611303

Start: 4834959

End: 4836758

Strand: Direct

Name: amaB [H]

Synonym: Veis_4389

Alternate gene names: 121611303

Gene position: 4834959-4836758 (Clockwise)

Preceding gene: 121611302

Following gene: 121611304

Centisome position: 86.85

GC content: 70.78

Gene sequence:

>1800_bases
ATGGCATTGACCCTGGAGCAATTGAACCGCGCCACCCCCGAGCAGGCCCTGCAGTGGCTCGACGGCCTGTACGAGCATTC
GCCCTGGGTGCTCGGGCAGGCACTGTCCGAGCGCCCGTTTCTGTCGCTGGCGCACCTGCGCCACGCGCTGGCGCAGGTGG
TGCGCAGGGCCGGCGCCGATGCGCAACGGGGCCTGATCCGCGCCCACCCCGAACTGGCCGGCCCGGCCATGCTGGCGCAC
AGCCTGAGCGCCGCATCGGCCCGCGAGCAAACGCAGGCCGGCCTGGCGCAGTGCAGCGCCGAGGAACTGGCCCGGCTGAG
GCAGCTCGATGCCGACTACCAGGCCCGCTTCGGTTTTCCGTTCATCCTGGCGCTGCGCGGCCCGCGCGGCAGCGGCCTGA
CCCGGCAGCAAATCCTGGCCTGCTTTGCGCGGCGCCTGGACAACCCCCCGGACTTCGAGCATGCCGAGGCCCTGCGCCAG
ATCCACCGCATCGCCGAACTGCGCCTGAACGACAGGTTCGGCGCCCAGCCCCGGCTGGGCAATGACCTGTGGGACTGGCA
CGAACGGTTGGCCGCGCATTCCGATCCCGGCTTTGCCGAGCAGGGCCAGCTCACCGTCACCTACCTGACGGACGCGCACC
GCGCCTGCGCCCGAACGCTGAGCGGCTGGATGCGCGCCTGCGGCTTCGACGAGGTGCACATCGATGCCGTGGGCAACGTG
GTCGGCCGCTACCACGCCAGCGACCCGCACGCCCGGGCCTTGCTGACCGGCAGCCACTACGACACCGTGCGCAATGGCGG
CAAGTACGACGGCCGCCTGGGCATCCTGGTGCCGATGGTCTGTGTGCGCGAATTGCAGCGCGCCGGCCGGCGCCTGCCCT
TCGGCATCGAAGTGGTGGCGTTCGCCGAAGAGGAGGGCCAGCGCTACCAGACCGCCTTTCTCGGCTCGGGCGCGCTGATC
GGGCAGTTCGATCCGGCATGGCTGGCGCAGCAGGACGCCGACGGCATCACGCTGCGCAGCGCCATGCAGCAGGCGGGCCT
GTGCGTCGCCGACATCGCCCGCTTGCAGCGCGACCCGGCCCGCTACCTGGGCTTTGTCGAAGTGCATATCGAGCAAGGCC
CGGTGCTGGGCGCGCTCGACCTGCCGCTGGGCGTGGTCAGTTCGATCAATGGCGGCCTGCGCTTGAGCGGCGAAATACAG
GGCCTGGCCAGCCACGCCGGCACCACCCCGATGGGACGCCGCCGCGACGCCGCGCTGGCGGTGGCCGAACTGGCGCTGTA
CGTCGAGCAGCGCGCCGCGCAGGACGGCGACTCGGTGGGCACCATCGGCCTGCTGGAAGTGCCGGGCGGCTCGGTGAATG
TGGTGCCGGGGCGTTGCCGGTTCAGTCTGGACCTGCGCGCGCCGGTCGATGCACAGCGCGACGCGCTGGCGCGGGACGTG
CTCGCGCAACTGGAGCGGATTGCCGCCAGGCGCGGGCTGCGCTACCAGTTGGCAGAAACGATGCGCGTCGCCGCCGCCCC
CTGCGCGCCCGCTTGGCAGCGCCGTTGGGAACGCGCCGTGGCCCGGCTCGGCCTGCCGGTATGGCGCATGCCCAGTGGCG
CCGGCCATGACGCAATGCAATTGCACGCCATCATGCCGCAGGCGATGCTGTTCGTGCGCGGCGAAAACGCCGGCATCAGC
CACAACCCGCTCGAATCGACCACCAGCGACGACATGCAACTGGCCGCAGAGGCGTTCACCGAATTGCTGCACCAACTGGC
CGAAGAGCAGGCCGAAGAACACACCGGAAAAGCCGTATGA

Upstream 100 bases:

>100_bases
AGCACGACAAGGTCTGGGTGGCCCGGCGCATCGACATCGCGCGCCACTGGCAAGCGCTGCACCCCTGCCCCGACCCTGCC
CAAGACAAGGGCCTGAAATG

Downstream 100 bases:

>100_bases
CGCCCGCCTGCCCCTACACCGCGCTCGATGCCTGGATCGAGCAGCATTTCGACGAACAAGTGCGCTTCTTGCAAGCGCTG
GTGCGCGTGCCCACCGACAC

Product: putative bifunctional OHCU decarboxylase/allantoate amidohydrolase

Products: NA

Alternate protein names: L-carbamoylase [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MALTLEQLNRATPEQALQWLDGLYEHSPWVLGQALSERPFLSLAHLRHALAQVVRRAGADAQRGLIRAHPELAGPAMLAH
SLSAASAREQTQAGLAQCSAEELARLRQLDADYQARFGFPFILALRGPRGSGLTRQQILACFARRLDNPPDFEHAEALRQ
IHRIAELRLNDRFGAQPRLGNDLWDWHERLAAHSDPGFAEQGQLTVTYLTDAHRACARTLSGWMRACGFDEVHIDAVGNV
VGRYHASDPHARALLTGSHYDTVRNGGKYDGRLGILVPMVCVRELQRAGRRLPFGIEVVAFAEEEGQRYQTAFLGSGALI
GQFDPAWLAQQDADGITLRSAMQQAGLCVADIARLQRDPARYLGFVEVHIEQGPVLGALDLPLGVVSSINGGLRLSGEIQ
GLASHAGTTPMGRRRDAALAVAELALYVEQRAAQDGDSVGTIGLLEVPGGSVNVVPGRCRFSLDLRAPVDAQRDALARDV
LAQLERIAARRGLRYQLAETMRVAAAPCAPAWQRRWERAVARLGLPVWRMPSGAGHDAMQLHAIMPQAMLFVRGENAGIS
HNPLESTTSDDMQLAAEAFTELLHQLAEEQAEEHTGKAV

Sequences:

>Translated_599_residues
MALTLEQLNRATPEQALQWLDGLYEHSPWVLGQALSERPFLSLAHLRHALAQVVRRAGADAQRGLIRAHPELAGPAMLAH
SLSAASAREQTQAGLAQCSAEELARLRQLDADYQARFGFPFILALRGPRGSGLTRQQILACFARRLDNPPDFEHAEALRQ
IHRIAELRLNDRFGAQPRLGNDLWDWHERLAAHSDPGFAEQGQLTVTYLTDAHRACARTLSGWMRACGFDEVHIDAVGNV
VGRYHASDPHARALLTGSHYDTVRNGGKYDGRLGILVPMVCVRELQRAGRRLPFGIEVVAFAEEEGQRYQTAFLGSGALI
GQFDPAWLAQQDADGITLRSAMQQAGLCVADIARLQRDPARYLGFVEVHIEQGPVLGALDLPLGVVSSINGGLRLSGEIQ
GLASHAGTTPMGRRRDAALAVAELALYVEQRAAQDGDSVGTIGLLEVPGGSVNVVPGRCRFSLDLRAPVDAQRDALARDV
LAQLERIAARRGLRYQLAETMRVAAAPCAPAWQRRWERAVARLGLPVWRMPSGAGHDAMQLHAIMPQAMLFVRGENAGIS
HNPLESTTSDDMQLAAEAFTELLHQLAEEQAEEHTGKAV
>Mature_598_residues
ALTLEQLNRATPEQALQWLDGLYEHSPWVLGQALSERPFLSLAHLRHALAQVVRRAGADAQRGLIRAHPELAGPAMLAHS
LSAASAREQTQAGLAQCSAEELARLRQLDADYQARFGFPFILALRGPRGSGLTRQQILACFARRLDNPPDFEHAEALRQI
HRIAELRLNDRFGAQPRLGNDLWDWHERLAAHSDPGFAEQGQLTVTYLTDAHRACARTLSGWMRACGFDEVHIDAVGNVV
GRYHASDPHARALLTGSHYDTVRNGGKYDGRLGILVPMVCVRELQRAGRRLPFGIEVVAFAEEEGQRYQTAFLGSGALIG
QFDPAWLAQQDADGITLRSAMQQAGLCVADIARLQRDPARYLGFVEVHIEQGPVLGALDLPLGVVSSINGGLRLSGEIQG
LASHAGTTPMGRRRDAALAVAELALYVEQRAAQDGDSVGTIGLLEVPGGSVNVVPGRCRFSLDLRAPVDAQRDALARDVL
AQLERIAARRGLRYQLAETMRVAAAPCAPAWQRRWERAVARLGLPVWRMPSGAGHDAMQLHAIMPQAMLFVRGENAGISH
NPLESTTSDDMQLAAEAFTELLHQLAEEQAEEHTGKAV

Specific function: Involved In The Anaerobic Utilization Of Allantoin. Converts Allantoate To (S)-Ureidoglycolate And Ammonia. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Homo sapiens, GI157743280, Length=175, Percent_Identity=34.2857142857143, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI1786726, Length=373, Percent_Identity=34.8525469168901, Blast_Score=175, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010158
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.87 [H]

Molecular weight: Translated: 65339; Mature: 65208

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTLEQLNRATPEQALQWLDGLYEHSPWVLGQALSERPFLSLAHLRHALAQVVRRAGAD
CCEEHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
AQRGLIRAHPELAGPAMLAHSLSAASAREQTQAGLAQCSAEELARLRQLDADYQARFGFP
HHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCC
FILALRGPRGSGLTRQQILACFARRLDNPPDFEHAEALRQIHRIAELRLNDRFGAQPRLG
EEEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NDLWDWHERLAAHSDPGFAEQGQLTVTYLTDAHRACARTLSGWMRACGFDEVHIDAVGNV
CHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
VGRYHASDPHARALLTGSHYDTVRNGGKYDGRLGILVPMVCVRELQRAGRRLPFGIEVVA
HHHCCCCCCCCEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
FAEEEGQRYQTAFLGSGALIGQFDPAWLAQQDADGITLRSAMQQAGLCVADIARLQRDPA
EECCCCCEEHHHHCCCCCEECCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHH
RYLGFVEVHIEQGPVLGALDLPLGVVSSINGGLRLSGEIQGLASHAGTTPMGRRRDAALA
HHEEEEEEEEECCCEEEEHHCCHHHHHHCCCCEEECCHHHHHHHHCCCCCCCCCHHHHHH
VAELALYVEQRAAQDGDSVGTIGLLEVPGGSVNVVPGRCRFSLDLRAPVDAQRDALARDV
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCHHHHHHHHHH
LAQLERIAARRGLRYQLAETMRVAAAPCAPAWQRRWERAVARLGLPVWRMPSGAGHDAMQ
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCHHH
LHAIMPQAMLFVRGENAGISHNPLESTTSDDMQLAAEAFTELLHQLAEEQAEEHTGKAV
HHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALTLEQLNRATPEQALQWLDGLYEHSPWVLGQALSERPFLSLAHLRHALAQVVRRAGAD
CEEHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
AQRGLIRAHPELAGPAMLAHSLSAASAREQTQAGLAQCSAEELARLRQLDADYQARFGFP
HHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCC
FILALRGPRGSGLTRQQILACFARRLDNPPDFEHAEALRQIHRIAELRLNDRFGAQPRLG
EEEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NDLWDWHERLAAHSDPGFAEQGQLTVTYLTDAHRACARTLSGWMRACGFDEVHIDAVGNV
CHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
VGRYHASDPHARALLTGSHYDTVRNGGKYDGRLGILVPMVCVRELQRAGRRLPFGIEVVA
HHHCCCCCCCCEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
FAEEEGQRYQTAFLGSGALIGQFDPAWLAQQDADGITLRSAMQQAGLCVADIARLQRDPA
EECCCCCEEHHHHCCCCCEECCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHH
RYLGFVEVHIEQGPVLGALDLPLGVVSSINGGLRLSGEIQGLASHAGTTPMGRRRDAALA
HHEEEEEEEEECCCEEEEHHCCHHHHHHCCCCEEECCHHHHHHHHCCCCCCCCCHHHHHH
VAELALYVEQRAAQDGDSVGTIGLLEVPGGSVNVVPGRCRFSLDLRAPVDAQRDALARDV
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCHHHHHHHHHH
LAQLERIAARRGLRYQLAETMRVAAAPCAPAWQRRWERAVARLGLPVWRMPSGAGHDAMQ
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCHHH
LHAIMPQAMLFVRGENAGISHNPLESTTSDDMQLAAEAFTELLHQLAEEQAEEHTGKAV
HHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9023955; 8285691 [H]