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The map label for this gene is sucD [H]

Identifier: 121611196

GI number: 121611196

Start: 4719393

End: 4720841

Strand: Direct

Name: sucD [H]

Synonym: Veis_4280

Alternate gene names: 121611196

Gene position: 4719393-4720841 (Clockwise)

Preceding gene: 121611195

Following gene: 121611197

Centisome position: 84.78

GC content: 70.05

Gene sequence:

>1449_bases
ATGGAACATTCCACTGCGCCCTCCAGCGCACCCTCGCCCATCACCGAACTGGTCGCGCGCGCCCGCGCCGCGCAACGCAT
CTGCGCCACCTGGTCGCAGGCGCAGGCGGACACCGCCGTGACTGCGGCCGGCTGGGCCATCATCGAGCCGGCGCGCAACC
GCGAACTGGCCGAGTTGGCCGTGGCCGACACCGGCATGGGCTGCGTTCAGGACAAGGTGCTGAAAAACCACCGCAAGACC
TTCGGCCTGCTGCGCGACCTGCACGGTGCGCGCTCGGTCGGCGTGATCGGCCAAGACCCGGCGCGCGGCATCGTCGAGAT
CGCGCGCCCCGTTGGCGTGGTGTGCGCCATCACGCCCTCGACCAACCCGGGCGCGACGCCGGCCAACAAGATCATCAATG
CGCTCAAGGGGCGCAACGCGGTCGTCGTCGCGCCCTCGCCCAAGGGCTGGTCGACGGCGGCGCGGCTGATCGGGTTCATC
CACGCGCAGTTCGATCGCATCGGCGCGCCGCGCGACCTGGTGCAACTGCTGCCTGGGCCTATCGACAAGCAGGCGACGGG
CGAACTGATGCGCCTGTGCGACCTGGTGGTGGCCACCGGCTCGCAGGCCAATGTGCGCGCGGCTTATGCCAGCGGCACGC
CGGCCTTCGGCGTGGGTGCGGGCAACGTGGCCGGCATCGTCGACGAAACGGCCGACGTGCACGCAGCGGCTGAGCGCATC
GTGCGCTCCAAGACCTTCGACAACGCGACCAGTTGCTCGTCGGAGAACAGCCTGGTGATCGTCGATGCGGTGCGTGCGCC
GATGCTCGCGGCGCTCGCAGAGCGCGGCGCGGTCATGCTCACGGCCGCGCAGAAGGCCACGCTGCAGGCGCTGATGTGGC
CCGGGGGCAAACTCTCGGCGGCCGTCATCGGCCAGTCGGCGCGCTCGATTGCCGAGCGCGCGGCGGCCCTGGACGACGCC
CAGTGCGCGGGCTGGCTGGCGCTTGCCGCGACCGGTCCGCGCATCCTGATGGTGGCCGAAGACGGCGCAGGCCATGGGCA
TCCGTTTTCGGGCGAAAAGCTCAGCCCCGTGCTCGCCATTCATGGCGCGCAAAATTTCGCCGCCGCCGCAGCCATGGTCG
AGCGCATCTACGCCCATGAAGGCGCCGGCCACTCGGTGGGCCTGCACAGCGCCCTGCCCGAACGCGCGCTCACGCTGGGC
CTGACGCTGCCGGTGGCGCGCGTGATCGTCGACCAGGCGCACAGCATCGCCACCGGCGGCAGCTTCGACAACGGGCTGCC
CTTCTCGCTCTCCATGGGCTGCGGCACCTGGGGCAAGAACAGCTTCTCGGACAACCTGAACTACCGCCACTACCTGAACA
TCACGCGGGTGTCGCGGCCGATACCGGAGCAGATGCCGAGCGCAGACGAGATCTTCGGCGACTTCTTCGCAAGGCACGGT
GCGCAGTGA

Upstream 100 bases:

>100_bases
ACGCCGGAGCAACTCGGCCAGATCGTCAGCGCCGAACTCGTGCGCTGGCAGCAACTGGCCAGGCAAGCCAACCTCCATCC
CGATTGACTGGCGGCTCCCC

Downstream 100 bases:

>100_bases
GCCGGCCGGCCGTCCCCACCGCTCCCGCCGCTCCCGCCGCCCTCACCGTCCACGCGCTGATCGGGCGACAGGCGGCGCAG
CGGCCACAGGCCGTGTACGC

Product: succinate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MEHSTAPSSAPSPITELVARARAAQRICATWSQAQADTAVTAAGWAIIEPARNRELAELAVADTGMGCVQDKVLKNHRKT
FGLLRDLHGARSVGVIGQDPARGIVEIARPVGVVCAITPSTNPGATPANKIINALKGRNAVVVAPSPKGWSTAARLIGFI
HAQFDRIGAPRDLVQLLPGPIDKQATGELMRLCDLVVATGSQANVRAAYASGTPAFGVGAGNVAGIVDETADVHAAAERI
VRSKTFDNATSCSSENSLVIVDAVRAPMLAALAERGAVMLTAAQKATLQALMWPGGKLSAAVIGQSARSIAERAAALDDA
QCAGWLALAATGPRILMVAEDGAGHGHPFSGEKLSPVLAIHGAQNFAAAAAMVERIYAHEGAGHSVGLHSALPERALTLG
LTLPVARVIVDQAHSIATGGSFDNGLPFSLSMGCGTWGKNSFSDNLNYRHYLNITRVSRPIPEQMPSADEIFGDFFARHG
AQ

Sequences:

>Translated_482_residues
MEHSTAPSSAPSPITELVARARAAQRICATWSQAQADTAVTAAGWAIIEPARNRELAELAVADTGMGCVQDKVLKNHRKT
FGLLRDLHGARSVGVIGQDPARGIVEIARPVGVVCAITPSTNPGATPANKIINALKGRNAVVVAPSPKGWSTAARLIGFI
HAQFDRIGAPRDLVQLLPGPIDKQATGELMRLCDLVVATGSQANVRAAYASGTPAFGVGAGNVAGIVDETADVHAAAERI
VRSKTFDNATSCSSENSLVIVDAVRAPMLAALAERGAVMLTAAQKATLQALMWPGGKLSAAVIGQSARSIAERAAALDDA
QCAGWLALAATGPRILMVAEDGAGHGHPFSGEKLSPVLAIHGAQNFAAAAAMVERIYAHEGAGHSVGLHSALPERALTLG
LTLPVARVIVDQAHSIATGGSFDNGLPFSLSMGCGTWGKNSFSDNLNYRHYLNITRVSRPIPEQMPSADEIFGDFFARHG
AQ
>Mature_482_residues
MEHSTAPSSAPSPITELVARARAAQRICATWSQAQADTAVTAAGWAIIEPARNRELAELAVADTGMGCVQDKVLKNHRKT
FGLLRDLHGARSVGVIGQDPARGIVEIARPVGVVCAITPSTNPGATPANKIINALKGRNAVVVAPSPKGWSTAARLIGFI
HAQFDRIGAPRDLVQLLPGPIDKQATGELMRLCDLVVATGSQANVRAAYASGTPAFGVGAGNVAGIVDETADVHAAAERI
VRSKTFDNATSCSSENSLVIVDAVRAPMLAALAERGAVMLTAAQKATLQALMWPGGKLSAAVIGQSARSIAERAAALDDA
QCAGWLALAATGPRILMVAEDGAGHGHPFSGEKLSPVLAIHGAQNFAAAAAMVERIYAHEGAGHSVGLHSALPERALTLG
LTLPVARVIVDQAHSIATGGSFDNGLPFSLSMGCGTWGKNSFSDNLNYRHYLNITRVSRPIPEQMPSADEIFGDFFARHG
AQ

Specific function: Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787493, Length=449, Percent_Identity=34.9665924276169, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1788797, Length=345, Percent_Identity=32.7536231884058, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.76 [H]

Molecular weight: Translated: 50039; Mature: 50039

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHSTAPSSAPSPITELVARARAAQRICATWSQAQADTAVTAAGWAIIEPARNRELAELA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCEEEECCCCCCHHHHHH
VADTGMGCVQDKVLKNHRKTFGLLRDLHGARSVGVIGQDPARGIVEIARPVGVVCAITPS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCC
TNPGATPANKIINALKGRNAVVVAPSPKGWSTAARLIGFIHAQFDRIGAPRDLVQLLPGP
CCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
IDKQATGELMRLCDLVVATGSQANVRAAYASGTPAFGVGAGNVAGIVDETADVHAAAERI
CCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
VRSKTFDNATSCSSENSLVIVDAVRAPMLAALAERGAVMLTAAQKATLQALMWPGGKLSA
HHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCCEEH
AVIGQSARSIAERAAALDDAQCAGWLALAATGPRILMVAEDGAGHGHPFSGEKLSPVLAI
HHHHHHHHHHHHHHHHCCCCHHHCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEE
HGAQNFAAAAAMVERIYAHEGAGHSVGLHSALPERALTLGLTLPVARVIVDQAHSIATGG
ECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
SFDNGLPFSLSMGCGTWGKNSFSDNLNYRHYLNITRVSRPIPEQMPSADEIFGDFFARHG
CCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHCCCHHHHHHHHHHHCC
AQ
CC
>Mature Secondary Structure
MEHSTAPSSAPSPITELVARARAAQRICATWSQAQADTAVTAAGWAIIEPARNRELAELA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCEEEECCCCCCHHHHHH
VADTGMGCVQDKVLKNHRKTFGLLRDLHGARSVGVIGQDPARGIVEIARPVGVVCAITPS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCC
TNPGATPANKIINALKGRNAVVVAPSPKGWSTAARLIGFIHAQFDRIGAPRDLVQLLPGP
CCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
IDKQATGELMRLCDLVVATGSQANVRAAYASGTPAFGVGAGNVAGIVDETADVHAAAERI
CCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
VRSKTFDNATSCSSENSLVIVDAVRAPMLAALAERGAVMLTAAQKATLQALMWPGGKLSA
HHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCCEEH
AVIGQSARSIAERAAALDDAQCAGWLALAATGPRILMVAEDGAGHGHPFSGEKLSPVLAI
HHHHHHHHHHHHHHHHCCCCHHHCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEE
HGAQNFAAAAAMVERIYAHEGAGHSVGLHSALPERALTLGLTLPVARVIVDQAHSIATGG
ECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
SFDNGLPFSLSMGCGTWGKNSFSDNLNYRHYLNITRVSRPIPEQMPSADEIFGDFFARHG
CCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHCCCHHHHHHHHHHHCC
AQ
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]