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The map label for this gene is fusA [C]

Identifier: 121611098

GI number: 121611098

Start: 4602672

End: 4604732

Strand: Direct

Name: fusA [C]

Synonym: Veis_4182

Alternate gene names: 121611098

Gene position: 4602672-4604732 (Clockwise)

Preceding gene: 121611095

Following gene: 121611099

Centisome position: 82.68

GC content: 69.24

Gene sequence:

>2061_bases
ATGCCAAGCCGATCGAACGGCCTCGCGGCCGAAGTGCAAGCCGTGCGAACCCTGGCGCTCGTGGGCGCCGCGGCTGCCGG
CAAAACCTCCCTCGCCGAGGCCTTGCTGTTCACGGCGGGTGCCATCGGGGCGTGCGGCAGCATCGAGCGCGGCAGCACCG
TCAGCGACCACGACCCGCTCGAGCGCCGCATGCTGCATTCGCTCAACGCCTCGGTGATGCACCTCACGCATGCCGCCACG
CGCATCCACCTCATCGACACGCCCGGCGGGCCCGACTTTTTGGGCCAGAGCCTGCCGGCGCTGGAGGCGGTCGAAACGGT
GGCGGTGGTCATCAATGCCGCCACCGGCATCGAGCCGATGGCCGTGCGCATGATGGACTACGCCGCCTCGCGCCACCTCG
CGCGCATGATCGTCGTCACCAAGATCGATTCGCAGGGCGTCTCGCTGGCCGGGCTGCTGGCCGACATCCAGGCCACCTTC
GGCCGCGAATGCCTGCCGCTGAACGTGCCCGACGGCGTCAACCGGCAGGTGATCGATTGTTTCTTCAACCGCTTCGGGCG
CTCCGACTTCGGACCGGTCGAGGCGGCGCACCGCGCGCTCGTCGAGCAGGTGGTCGAGGTCGATGCGGCCTTCGTCGAGC
GCTACCTCGAGGAAGGCGACGTGGACCCGTCCGAGCTGCACGCGCCGCTCGAGCAGGCGCTGCGCGAAGGCCACCTGATT
CCCGTGTGCTTTGTCTCGTCGCGCAGCGGTGCCGGCGTGGCCGAGCTGCTCGACATGATCGTCAAGTTCCTGCCCGACCC
GACCGAGGGCAACCCGCCGGAGTTCATGGTCGGCGAGGGCGCGCAGGCCCAGCCCATGAAGGCCCTGCCCGATCCGTCGC
TGCATGTGCTGGCGCATGTGTTCAAGGTCACCATCGACGCGTACGTCGGCAAGATGGGCATCTTCCGCGTGCACCAGGGC
ACGGTCACGCGCGACAGCCAGCTCTACATCGGCGACGGCCGCAAACCCTTCAAGGTGGGGCACCTGTTCATGCTCCAGGG
CAAGGACCATGTCGAGGTGTCGCGCGCGCTGCCCGGCGACATCGTGGCCGTGGCCAAGGTCGATGAGATCCATTTCGATG
CCGTGCTCCACGATGCCGCCGAAGACAGCCACGTGCACCTGGCGCCGCTGCCGTTCCCCGTGCCCGTGTACGGCCTGGCC
ATCGAGCCCAAGCGCCACGGCGACGAACAGCGCGCCTGGGAAATCCTCGGCAAGCTCGCGGCCGAAGACCCGTGCCTGCG
CATCGAGCATGTGGCCGCGACCAACGAGACCGTGCTCTACGGCCTGGGCGAGCTGCACCTGCGCATCGCGCTCGAACGCC
TGCGCGAGGTGTACCACTTCGAGGTGCTGACGCGGCCGCCGCGCATCGCCTACCGCGAGACCGTGACCGCGCCGGCCGAG
GGCCACCACCGCCACAAGAAGCAGAGCGGCGGTGCCGGCCAGTTCGCCGAAGTCTTCCTGCGCATCGAGCCACTCGCGCG
CGGCGCGGGCTTCGCGTTCGCCGACGAAGTCAGGGGCGGCGCGATCCCGAGCCAGTTCATCCCTGCGGTCGAGAAAGGCG
TGCGCGAGGTGCTGGCCTACGGCGCGATCGCCGGCTACCCCGTGGTCGACGTGCGCGTCGTGGTGTACGACGGCAAGCAC
CACAGCGTCGACAGCAAGGACATCGCCTTCGCGACCGCCGGTCGCAAGGCCTTCATGGCCGCGATCCGCGAGGCCCGTCC
GGCCGTGCTCGAACCGATCGTGCAGATCGAGATCGCCGTGCCCGAGCATTCGGTGGGCGATGTCACGAGCGACCTGTCGT
CGCGGCGCGGCCTCATCACCGGCACCTCCGGCGAGGGCGGCGGTACCGTGGCCATCGGCGGCCAGGTGCCCGAGGTCGAG
CTGGCCAACTACCAGTCGCTGCTGCATGCGATGACCAGCGGCCAGGGCCGCTACACCATTGCGTTGTCGCACTACGAGGC
CGTGCCACCGGCTGTGCAGAAGACGCTGATGGGCGAGTACCGGGGGCGTGAAGAGGAGTAG

Upstream 100 bases:

>100_bases
CGCCCGGTCAATCCCGTACGCTGGCCCGGCGTCCATGCGCACCGTCCGAGCCCTTGCGGGCCGCCGGGCCGGCCTTGCGG
ACGCGCAAAGGAGACCCGCC

Downstream 100 bases:

>100_bases
GCGCGCGCAGGGCCCTTCATTCGAACCTGATGGCCTGAGCGCCCTACCTGGCGCGATTCAAAGCGGCCGCCGGATCGGCG
CGCGCCACGACGGGCCTGTG

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MPSRSNGLAAEVQAVRTLALVGAAAAGKTSLAEALLFTAGAIGACGSIERGSTVSDHDPLERRMLHSLNASVMHLTHAAT
RIHLIDTPGGPDFLGQSLPALEAVETVAVVINAATGIEPMAVRMMDYAASRHLARMIVVTKIDSQGVSLAGLLADIQATF
GRECLPLNVPDGVNRQVIDCFFNRFGRSDFGPVEAAHRALVEQVVEVDAAFVERYLEEGDVDPSELHAPLEQALREGHLI
PVCFVSSRSGAGVAELLDMIVKFLPDPTEGNPPEFMVGEGAQAQPMKALPDPSLHVLAHVFKVTIDAYVGKMGIFRVHQG
TVTRDSQLYIGDGRKPFKVGHLFMLQGKDHVEVSRALPGDIVAVAKVDEIHFDAVLHDAAEDSHVHLAPLPFPVPVYGLA
IEPKRHGDEQRAWEILGKLAAEDPCLRIEHVAATNETVLYGLGELHLRIALERLREVYHFEVLTRPPRIAYRETVTAPAE
GHHRHKKQSGGAGQFAEVFLRIEPLARGAGFAFADEVRGGAIPSQFIPAVEKGVREVLAYGAIAGYPVVDVRVVVYDGKH
HSVDSKDIAFATAGRKAFMAAIREARPAVLEPIVQIEIAVPEHSVGDVTSDLSSRRGLITGTSGEGGGTVAIGGQVPEVE
LANYQSLLHAMTSGQGRYTIALSHYEAVPPAVQKTLMGEYRGREEE

Sequences:

>Translated_686_residues
MPSRSNGLAAEVQAVRTLALVGAAAAGKTSLAEALLFTAGAIGACGSIERGSTVSDHDPLERRMLHSLNASVMHLTHAAT
RIHLIDTPGGPDFLGQSLPALEAVETVAVVINAATGIEPMAVRMMDYAASRHLARMIVVTKIDSQGVSLAGLLADIQATF
GRECLPLNVPDGVNRQVIDCFFNRFGRSDFGPVEAAHRALVEQVVEVDAAFVERYLEEGDVDPSELHAPLEQALREGHLI
PVCFVSSRSGAGVAELLDMIVKFLPDPTEGNPPEFMVGEGAQAQPMKALPDPSLHVLAHVFKVTIDAYVGKMGIFRVHQG
TVTRDSQLYIGDGRKPFKVGHLFMLQGKDHVEVSRALPGDIVAVAKVDEIHFDAVLHDAAEDSHVHLAPLPFPVPVYGLA
IEPKRHGDEQRAWEILGKLAAEDPCLRIEHVAATNETVLYGLGELHLRIALERLREVYHFEVLTRPPRIAYRETVTAPAE
GHHRHKKQSGGAGQFAEVFLRIEPLARGAGFAFADEVRGGAIPSQFIPAVEKGVREVLAYGAIAGYPVVDVRVVVYDGKH
HSVDSKDIAFATAGRKAFMAAIREARPAVLEPIVQIEIAVPEHSVGDVTSDLSSRRGLITGTSGEGGGTVAIGGQVPEVE
LANYQSLLHAMTSGQGRYTIALSHYEAVPPAVQKTLMGEYRGREEE
>Mature_685_residues
PSRSNGLAAEVQAVRTLALVGAAAAGKTSLAEALLFTAGAIGACGSIERGSTVSDHDPLERRMLHSLNASVMHLTHAATR
IHLIDTPGGPDFLGQSLPALEAVETVAVVINAATGIEPMAVRMMDYAASRHLARMIVVTKIDSQGVSLAGLLADIQATFG
RECLPLNVPDGVNRQVIDCFFNRFGRSDFGPVEAAHRALVEQVVEVDAAFVERYLEEGDVDPSELHAPLEQALREGHLIP
VCFVSSRSGAGVAELLDMIVKFLPDPTEGNPPEFMVGEGAQAQPMKALPDPSLHVLAHVFKVTIDAYVGKMGIFRVHQGT
VTRDSQLYIGDGRKPFKVGHLFMLQGKDHVEVSRALPGDIVAVAKVDEIHFDAVLHDAAEDSHVHLAPLPFPVPVYGLAI
EPKRHGDEQRAWEILGKLAAEDPCLRIEHVAATNETVLYGLGELHLRIALERLREVYHFEVLTRPPRIAYRETVTAPAEG
HHRHKKQSGGAGQFAEVFLRIEPLARGAGFAFADEVRGGAIPSQFIPAVEKGVREVLAYGAIAGYPVVDVRVVVYDGKHH
SVDSKDIAFATAGRKAFMAAIREARPAVLEPIVQIEIAVPEHSVGDVTSDLSSRRGLITGTSGEGGGTVAIGGQVPEVEL
ANYQSLLHAMTSGQGRYTIALSHYEAVPPAVQKTLMGEYRGREEE

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=696, Percent_Identity=28.1609195402299, Blast_Score=288, Evalue=1e-77,
Organism=Homo sapiens, GI19923640, Length=729, Percent_Identity=24.5541838134431, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI25306287, Length=308, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI25306283, Length=380, Percent_Identity=23.6842105263158, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1789738, Length=702, Percent_Identity=29.7720797720798, Blast_Score=322, Evalue=5e-89,
Organism=Escherichia coli, GI1790835, Length=497, Percent_Identity=20.9255533199195, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17533571, Length=708, Percent_Identity=28.2485875706215, Blast_Score=268, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI17556745, Length=687, Percent_Identity=22.707423580786, Blast_Score=135, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6323098, Length=704, Percent_Identity=26.7045454545455, Blast_Score=256, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6322359, Length=783, Percent_Identity=23.2439335887612, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324707, Length=804, Percent_Identity=21.6417910447761, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320593, Length=804, Percent_Identity=21.6417910447761, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24582462, Length=700, Percent_Identity=28, Blast_Score=275, Evalue=9e-74,
Organism=Drosophila melanogaster, GI221458488, Length=704, Percent_Identity=24.5738636363636, Blast_Score=181, Evalue=1e-45,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 73725; Mature: 73594

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSRSNGLAAEVQAVRTLALVGAAAAGKTSLAEALLFTAGAIGACGSIERGSTVSDHDPL
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
ERRMLHSLNASVMHLTHAATRIHLIDTPGGPDFLGQSLPALEAVETVAVVINAATGIEPM
HHHHHHHHCHHHHHEEEHEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCHH
AVRMMDYAASRHLARMIVVTKIDSQGVSLAGLLADIQATFGRECLPLNVPDGVNRQVIDC
HHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHH
FFNRFGRSDFGPVEAAHRALVEQVVEVDAAFVERYLEEGDVDPSELHAPLEQALREGHLI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
PVCFVSSRSGAGVAELLDMIVKFLPDPTEGNPPEFMVGEGAQAQPMKALPDPSLHVLAHV
EEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHH
FKVTIDAYVGKMGIFRVHQGTVTRDSQLYIGDGRKPFKVGHLFMLQGKDHVEVSRALPGD
HHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHCCCCC
IVAVAKVDEIHFDAVLHDAAEDSHVHLAPLPFPVPVYGLAIEPKRHGDEQRAWEILGKLA
EEEEEEECHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEECCHHCCCHHHHHHHHHHHH
AEDPCLRIEHVAATNETVLYGLGELHLRIALERLREVYHFEVLTRPPRIAYRETVTAPAE
CCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCCCCCC
GHHRHKKQSGGAGQFAEVFLRIEPLARGAGFAFADEVRGGAIPSQFIPAVEKGVREVLAY
CCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHH
GAIAGYPVVDVRVVVYDGKHHSVDSKDIAFATAGRKAFMAAIREARPAVLEPIVQIEIAV
HCCCCCCEEEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHCCEEEEEEEC
PEHSVGDVTSDLSSRRGLITGTSGEGGGTVAIGGQVPEVELANYQSLLHAMTSGQGRYTI
CCCCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEE
ALSHYEAVPPAVQKTLMGEYRGREEE
EECCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PSRSNGLAAEVQAVRTLALVGAAAAGKTSLAEALLFTAGAIGACGSIERGSTVSDHDPL
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
ERRMLHSLNASVMHLTHAATRIHLIDTPGGPDFLGQSLPALEAVETVAVVINAATGIEPM
HHHHHHHHCHHHHHEEEHEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCHH
AVRMMDYAASRHLARMIVVTKIDSQGVSLAGLLADIQATFGRECLPLNVPDGVNRQVIDC
HHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHH
FFNRFGRSDFGPVEAAHRALVEQVVEVDAAFVERYLEEGDVDPSELHAPLEQALREGHLI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
PVCFVSSRSGAGVAELLDMIVKFLPDPTEGNPPEFMVGEGAQAQPMKALPDPSLHVLAHV
EEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHH
FKVTIDAYVGKMGIFRVHQGTVTRDSQLYIGDGRKPFKVGHLFMLQGKDHVEVSRALPGD
HHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHCCCCC
IVAVAKVDEIHFDAVLHDAAEDSHVHLAPLPFPVPVYGLAIEPKRHGDEQRAWEILGKLA
EEEEEEECHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEECCHHCCCHHHHHHHHHHHH
AEDPCLRIEHVAATNETVLYGLGELHLRIALERLREVYHFEVLTRPPRIAYRETVTAPAE
CCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCCCCCC
GHHRHKKQSGGAGQFAEVFLRIEPLARGAGFAFADEVRGGAIPSQFIPAVEKGVREVLAY
CCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHH
GAIAGYPVVDVRVVVYDGKHHSVDSKDIAFATAGRKAFMAAIREARPAVLEPIVQIEIAV
HCCCCCCEEEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHCCEEEEEEEC
PEHSVGDVTSDLSSRRGLITGTSGEGGGTVAIGGQVPEVELANYQSLLHAMTSGQGRYTI
CCCCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEE
ALSHYEAVPPAVQKTLMGEYRGREEE
EECCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]