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The map label for this gene is etfA [H]

Identifier: 121610971

GI number: 121610971

Start: 4447706

End: 4448914

Strand: Direct

Name: etfA [H]

Synonym: Veis_4055

Alternate gene names: 121610971

Gene position: 4447706-4448914 (Clockwise)

Preceding gene: 121610970

Following gene: 121610972

Centisome position: 79.9

GC content: 73.45

Gene sequence:

>1209_bases
ATGACCACCGCCCGGCCACCCGAAAGCGCCCATGCCGCAGCCGAAGGCGGAGGCACTCCAGTGAGCACCACCCCGGTACC
CCGCATCGACCCGCGCCGCCCGGCAATCACCACGGCGCAGGGGCTGCGCCGCATCGTGCCCGGCCACCGCGCCGCTGCGC
CGCCGACCGCCCGGCAGGCCGGCCCGGGCGCACCGCTTGCCAGTCCGGGCGCCCATCCGGGCGCCAAACCGCTGCGCAGC
GCCGGCCCGTTCAACCGCAGCACGCTGGTCGTGACCCATGCCGAGCGCGGCACATTGACCGATGCGGCGCGCCAGGCGCT
GGCGGCAGCGGCCATCCTGGCCAGCGCCGAGACCCAGGTCGTGCTGGCCGTGCTGGGCCCCTGCCGCGATGGCAGCGACG
CCGTGGCGGCGCTCGGCGCCGATCGCCTGCTGGCATTGGACAGCTTCGACGCCAGCCGCTACCAACCCGGCGCCTGCGTG
CAATGGCTGCAAGCGCTGCATGCGGCCTGGGCCCCTGCGCATTGGCTGTTCGCCGACAGCGGGGCCGACGGCGAACTGGG
CCGGCGGTTTGCACTGCACACCGGGCTGGGGCTCGCCTGCGGCGTGGTGGAACTGGGCGCCGAGAGCCTGCGCATACGCG
CCAGCGCCAGCGACGACTGGCTGTGCCCGCATGCCCCGGTGATGCTGCTGGCCCCGGGCCTGGCCAGCACCCGGCTGCCG
TTTGTCGGCCAGGGGCTGCGCGCCGCCGCGCCAGCGCTGCCGGCCCTGCCCGAGCCGGGCATCGAAGACCTGGGCGTGCA
GCCGGGCGACCCGCAGAGCTTGGCGCTGGAAGAGGCCGATCTGATCCTGGCCGCCGGCAATGGGGTCCGGCACGGCGATT
TGCCGCTGCTGCATGCGCTGGCGCAGGAGATCGGCGCCAGCGTCGGGGCCTCGCGCGTTGCGGTCGACGCCGGGCACTTT
GCCCGCCACCAGCAAATCGGCGCCACCGGCAAGGCCGTTTCGGCATCGGCCTATCTGGCGCTGGGCATCTCGGGCGCGGT
GCAGCATCTGCAAGGCATCAAGGACTGCCGCCATGTGATCGCGGTGAACCTGGACGCATCGGCCCCGATCACCGGCCGCG
CCCATCTGAGCGTGATCGAAGACAGCGCGGCGCTGATGCAAGCGCTGATCGAACTGGTGCGCAAGGAAAGGGACAAGGCC
GGCGCATGA

Upstream 100 bases:

>100_bases
CGAAAGCGCTCATACCGCAGCCGAAGGCGAAGGCACTCCAGTGAGCACCGCACGGCCACCCGAAAGCGCTCATGCCGCAG
CCGAAGGCGGAGGCACTCCA

Downstream 100 bases:

>100_bases
ACCACCCGATGAGCCACCCGATGAATCACCCCATGCGCCACCCCGTCACCGTGCTGGTGGCCCCGCGCAGCCACCCCGTC
AGCCAGCGCCCGACCCGCTG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTTARPPESAHAAAEGGGTPVSTTPVPRIDPRRPAITTAQGLRRIVPGHRAAAPPTARQAGPGAPLASPGAHPGAKPLRS
AGPFNRSTLVVTHAERGTLTDAARQALAAAAILASAETQVVLAVLGPCRDGSDAVAALGADRLLALDSFDASRYQPGACV
QWLQALHAAWAPAHWLFADSGADGELGRRFALHTGLGLACGVVELGAESLRIRASASDDWLCPHAPVMLLAPGLASTRLP
FVGQGLRAAAPALPALPEPGIEDLGVQPGDPQSLALEEADLILAAGNGVRHGDLPLLHALAQEIGASVGASRVAVDAGHF
ARHQQIGATGKAVSASAYLALGISGAVQHLQGIKDCRHVIAVNLDASAPITGRAHLSVIEDSAALMQALIELVRKERDKA
GA

Sequences:

>Translated_402_residues
MTTARPPESAHAAAEGGGTPVSTTPVPRIDPRRPAITTAQGLRRIVPGHRAAAPPTARQAGPGAPLASPGAHPGAKPLRS
AGPFNRSTLVVTHAERGTLTDAARQALAAAAILASAETQVVLAVLGPCRDGSDAVAALGADRLLALDSFDASRYQPGACV
QWLQALHAAWAPAHWLFADSGADGELGRRFALHTGLGLACGVVELGAESLRIRASASDDWLCPHAPVMLLAPGLASTRLP
FVGQGLRAAAPALPALPEPGIEDLGVQPGDPQSLALEEADLILAAGNGVRHGDLPLLHALAQEIGASVGASRVAVDAGHF
ARHQQIGATGKAVSASAYLALGISGAVQHLQGIKDCRHVIAVNLDASAPITGRAHLSVIEDSAALMQALIELVRKERDKA
GA
>Mature_401_residues
TTARPPESAHAAAEGGGTPVSTTPVPRIDPRRPAITTAQGLRRIVPGHRAAAPPTARQAGPGAPLASPGAHPGAKPLRSA
GPFNRSTLVVTHAERGTLTDAARQALAAAAILASAETQVVLAVLGPCRDGSDAVAALGADRLLALDSFDASRYQPGACVQ
WLQALHAAWAPAHWLFADSGADGELGRRFALHTGLGLACGVVELGAESLRIRASASDDWLCPHAPVMLLAPGLASTRLPF
VGQGLRAAAPALPALPEPGIEDLGVQPGDPQSLALEEADLILAAGNGVRHGDLPLLHALAQEIGASVGASRVAVDAGHFA
RHQQIGATGKAVSASAYLALGISGAVQHLQGIKDCRHVIAVNLDASAPITGRAHLSVIEDSAALMQALIELVRKERDKAG
A

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=122, Percent_Identity=40.1639344262295, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4503607, Length=122, Percent_Identity=40.1639344262295, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1787990, Length=120, Percent_Identity=34.1666666666667, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082157, Length=252, Percent_Identity=27.3809523809524, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786226, Length=135, Percent_Identity=28.1481481481481, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17506929, Length=132, Percent_Identity=41.6666666666667, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325261, Length=102, Percent_Identity=41.1764705882353, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17136898, Length=118, Percent_Identity=46.6101694915254, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24652801, Length=118, Percent_Identity=46.6101694915254, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 40907; Mature: 40776

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTARPPESAHAAAEGGGTPVSTTPVPRIDPRRPAITTAQGLRRIVPGHRAAAPPTARQA
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
GPGAPLASPGAHPGAKPLRSAGPFNRSTLVVTHAERGTLTDAARQALAAAAILASAETQV
CCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEE
VLAVLGPCRDGSDAVAALGADRLLALDSFDASRYQPGACVQWLQALHAAWAPAHWLFADS
EEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECC
GADGELGRRFALHTGLGLACGVVELGAESLRIRASASDDWLCPHAPVMLLAPGLASTRLP
CCCHHHHCEEHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCC
FVGQGLRAAAPALPALPEPGIEDLGVQPGDPQSLALEEADLILAAGNGVRHGDLPLLHAL
CCCCCHHHHCCCCCCCCCCCHHHCCCCCCCCHHEECCCCCEEEECCCCCCCCCHHHHHHH
AQEIGASVGASRVAVDAGHFARHQQIGATGKAVSASAYLALGISGAVQHLQGIKDCRHVI
HHHHHHHCCCCCEEECCHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHEE
AVNLDASAPITGRAHLSVIEDSAALMQALIELVRKERDKAGA
EEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTARPPESAHAAAEGGGTPVSTTPVPRIDPRRPAITTAQGLRRIVPGHRAAAPPTARQA
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
GPGAPLASPGAHPGAKPLRSAGPFNRSTLVVTHAERGTLTDAARQALAAAAILASAETQV
CCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEE
VLAVLGPCRDGSDAVAALGADRLLALDSFDASRYQPGACVQWLQALHAAWAPAHWLFADS
EEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECC
GADGELGRRFALHTGLGLACGVVELGAESLRIRASASDDWLCPHAPVMLLAPGLASTRLP
CCCHHHHCEEHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCC
FVGQGLRAAAPALPALPEPGIEDLGVQPGDPQSLALEEADLILAAGNGVRHGDLPLLHAL
CCCCCHHHHCCCCCCCCCCCHHHCCCCCCCCHHEECCCCCEEEECCCCCCCCCHHHHHHH
AQEIGASVGASRVAVDAGHFARHQQIGATGKAVSASAYLALGISGAVQHLQGIKDCRHVI
HHHHHHHCCCCCEEECCHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHEE
AVNLDASAPITGRAHLSVIEDSAALMQALIELVRKERDKAGA
EEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]