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The map label for this gene is emrD [C]

Identifier: 121610881

GI number: 121610881

Start: 4348642

End: 4349799

Strand: Direct

Name: emrD [C]

Synonym: Veis_3963

Alternate gene names: 121610881

Gene position: 4348642-4349799 (Clockwise)

Preceding gene: 121610877

Following gene: 121610888

Centisome position: 78.12

GC content: 68.31

Gene sequence:

>1158_bases
ATGCAAACACAACAGATTGCCGCGCTCTTCGCTTGCCTTTTTCTCATCGGCTCGGCGGAGGTCGTCGCCGGGCCGATGAT
GAGCGCGATGAGCGTCGATTTCGGCGTTCGCTCCAGCGCCATCGCCTATCTGCCAGCCGCTTATGGCCTGAGCTATGGCG
CGGTCGCGTTGATCGCGGGGCCGCTGTCGGACCGATGGGGGCGCAAGCTGCCGCTGCAAGCGGGACTGCTTGGCTTCGCC
CTGCTCAACGCATCCATCCCCGGCGCTGCGCATTTGCCGGCAGCGATCGTCCTGTCCGCATTGGCCGGCCTGTGCGCGGC
GATCATTCAGCCCAACGCGCTGTCCCTGGTAGCCGACGAATCACCGCCCGAGCAGGTCGGCCGCCGCCTCGGCCAGGTGT
TCATCGGCCTGATGCTGGCCTTCGTGCTCACCCCCGTTCTCGCAGGGCAGTTGGCGGACACCCTGGGTTGGCGCTCGGCC
TACTACGCGCTGGCGCTGCTGTCCGTGCTGGCCTGGCTGGCCGTGACACGGGCCTTTGCCCGCCGCCCGCCGGGCGCCGG
GGCCAGAACGGACTTCCTGAGCACGCACCGGCAGGCGTGGCGCACGATCGATGTTCGCCGTCGGCTGTCGGTCAGCTATC
TCTGGCTCGGCTGGCTGGCCGGGTTCGGCGCCGTGGTGGCGGAAGTTGCGGCCCGCAAGCTCCCGTTGTCGCCGACGGAT
ACCGGCCTGATCGCGGGCTTTTTCGGCCTGGCCGTGATCGCCGGGAATCTTGCGGGCGCCCGCCTGCACCGGGCGCTCGG
ACAAGCCGCGCTGCCGGTGATGGCCATCGTCGCGGCCCTGGGCCTGCTCGGCTTCATGCTGCCGGTCGAGTCCATGGCGC
AGTTGCTCCTGCTCGGGTTGCCGTGGGCATTCGGCTACGGCTGCGCGGGTCCGTTGCACCACGCGAGACTCAGCGCGCTG
TCGGAGCGCTACCGGGGCACCATCAATTCATACCATGCCAGTCTGCTCAATCTCGGCATTTTCTCGGTGTCGTTCCTGCT
GGGCGCGGTGGTGCCGCACTTTCCGGTGACGCTGTTCTGCGCGCTGGTGGGGGCCGTCACGCTGGTCGGGGCGTGTCTTT
TGCTCCCCTGGCCGCGTTTATCGATCACCACCCGGTGA

Upstream 100 bases:

>100_bases
GGGCTCGGAATTGACTTTTTCTGACGCGCTTGGCGTGCGCCAGGCGCAAGAACCACGGCCATCCCGGCGCATCCGCACCA
CCTGAAGGGCCGTGGGAATC

Downstream 100 bases:

>100_bases
TGGCTCGCCGGGTAAGACGGTCACTGTGCGCGCCGCGCGACGACATCGAGCATGGCAAGCGCTTTGTCTGACAGCAGTTT
GTGCATCCCCGGTGTGCCGT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Facilitator Transporter

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQTQQIAALFACLFLIGSAEVVAGPMMSAMSVDFGVRSSAIAYLPAAYGLSYGAVALIAGPLSDRWGRKLPLQAGLLGFA
LLNASIPGAAHLPAAIVLSALAGLCAAIIQPNALSLVADESPPEQVGRRLGQVFIGLMLAFVLTPVLAGQLADTLGWRSA
YYALALLSVLAWLAVTRAFARRPPGAGARTDFLSTHRQAWRTIDVRRRLSVSYLWLGWLAGFGAVVAEVAARKLPLSPTD
TGLIAGFFGLAVIAGNLAGARLHRALGQAALPVMAIVAALGLLGFMLPVESMAQLLLLGLPWAFGYGCAGPLHHARLSAL
SERYRGTINSYHASLLNLGIFSVSFLLGAVVPHFPVTLFCALVGAVTLVGACLLLPWPRLSITTR

Sequences:

>Translated_385_residues
MQTQQIAALFACLFLIGSAEVVAGPMMSAMSVDFGVRSSAIAYLPAAYGLSYGAVALIAGPLSDRWGRKLPLQAGLLGFA
LLNASIPGAAHLPAAIVLSALAGLCAAIIQPNALSLVADESPPEQVGRRLGQVFIGLMLAFVLTPVLAGQLADTLGWRSA
YYALALLSVLAWLAVTRAFARRPPGAGARTDFLSTHRQAWRTIDVRRRLSVSYLWLGWLAGFGAVVAEVAARKLPLSPTD
TGLIAGFFGLAVIAGNLAGARLHRALGQAALPVMAIVAALGLLGFMLPVESMAQLLLLGLPWAFGYGCAGPLHHARLSAL
SERYRGTINSYHASLLNLGIFSVSFLLGAVVPHFPVTLFCALVGAVTLVGACLLLPWPRLSITTR
>Mature_385_residues
MQTQQIAALFACLFLIGSAEVVAGPMMSAMSVDFGVRSSAIAYLPAAYGLSYGAVALIAGPLSDRWGRKLPLQAGLLGFA
LLNASIPGAAHLPAAIVLSALAGLCAAIIQPNALSLVADESPPEQVGRRLGQVFIGLMLAFVLTPVLAGQLADTLGWRSA
YYALALLSVLAWLAVTRAFARRPPGAGARTDFLSTHRQAWRTIDVRRRLSVSYLWLGWLAGFGAVVAEVAARKLPLSPTD
TGLIAGFFGLAVIAGNLAGARLHRALGQAALPVMAIVAALGLLGFMLPVESMAQLLLLGLPWAFGYGCAGPLHHARLSAL
SERYRGTINSYHASLLNLGIFSVSFLLGAVVPHFPVTLFCALVGAVTLVGACLLLPWPRLSITTR

Specific function: Multidrug Resistance Pump That Participates In A Low Energy Shock Adaptative Response. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40310; Mature: 40310

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTQQIAALFACLFLIGSAEVVAGPMMSAMSVDFGVRSSAIAYLPAAYGLSYGAVALIAG
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHCC
PLSDRWGRKLPLQAGLLGFALLNASIPGAAHLPAAIVLSALAGLCAAIIQPNALSLVADE
CHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
SPPEQVGRRLGQVFIGLMLAFVLTPVLAGQLADTLGWRSAYYALALLSVLAWLAVTRAFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRPPGAGARTDFLSTHRQAWRTIDVRRRLSVSYLWLGWLAGFGAVVAEVAARKLPLSPTD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TGLIAGFFGLAVIAGNLAGARLHRALGQAALPVMAIVAALGLLGFMLPVESMAQLLLLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PWAFGYGCAGPLHHARLSALSERYRGTINSYHASLLNLGIFSVSFLLGAVVPHFPVTLFC
CHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVGAVTLVGACLLLPWPRLSITTR
HHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQTQQIAALFACLFLIGSAEVVAGPMMSAMSVDFGVRSSAIAYLPAAYGLSYGAVALIAG
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHCC
PLSDRWGRKLPLQAGLLGFALLNASIPGAAHLPAAIVLSALAGLCAAIIQPNALSLVADE
CHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
SPPEQVGRRLGQVFIGLMLAFVLTPVLAGQLADTLGWRSAYYALALLSVLAWLAVTRAFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRPPGAGARTDFLSTHRQAWRTIDVRRRLSVSYLWLGWLAGFGAVVAEVAARKLPLSPTD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TGLIAGFFGLAVIAGNLAGARLHRALGQAALPVMAIVAALGLLGFMLPVESMAQLLLLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PWAFGYGCAGPLHHARLSALSERYRGTINSYHASLLNLGIFSVSFLLGAVVPHFPVTLFC
CHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVGAVTLVGACLLLPWPRLSITTR
HHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA