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The map label for this gene is xylR [H]

Identifier: 121609746

GI number: 121609746

Start: 3142569

End: 3144251

Strand: Direct

Name: xylR [H]

Synonym: Veis_2797

Alternate gene names: 121609746

Gene position: 3142569-3144251 (Clockwise)

Preceding gene: 121609727

Following gene: 121609747

Centisome position: 56.45

GC content: 69.82

Gene sequence:

>1683_bases
GTGGAACCGCATCTGAACTACCCTCCGGACGCCGACCTGAGGAAACTGCTCCGCTTCGAGCCCGACAGCGGGGCCATCTG
GCTCGGCGAGCGCCGCATGGTCCTGCTGCACACGGCGGCGCTGAGTGCGTTGCGCCGCGACCTGATCACCTCGGTCGGCA
CCGACCACGCCCGCCGCCTGCTCACGCGCATGGGCTACGCCAGCGGTCTGCACGACGCCGGCTTTGCCAACAAGACCCGG
GGTGACTGCAGCCTGGAAGACATGTTCCTCGTGGGGCCTCAACTGCACATGCTCGAAGGCGCGGCCCGGGTCACGCCACT
GCACCTGAAGATGGACGCGGCTGCGGGCCTGTTCGAGGGCGAGTTCCGGTGGGACGATTCCTGGGAGGCCCATGCCCACC
GCCTGGCCTACGGCGTGGTGGACGAGCCGGCCTGCTGGATCCTGCTGGGCTACGCCAGCGGCTACACCAGCGCGTTCATG
GGCAAGCTGATCCTGTTCAAGGAAATCCGGTGCGGCGCCTGCGGAGACGAGCACTGCCACATCGTGGGCAAGCCGATCGA
CGAATGGCCTGACGGCGCGGCCTACGGCCAATACTTCGAAGACGATTCGCTGCTGGACAAGATGGACGCGCTGAGCCAGC
AGGTGCAGGCGCTCAAGACCACGCTGGAGCCCACGACTTCTGGCGGCATGCTGGTCGGGAATTCGCCGGCGTTCCAGCAG
GCGCACAATCTCATGCAGCGTGCCGCGCAGACCCAGGTCACGGTGCTGCTGACCGGCGAGACCGGGGTTGGCAAAGAGCG
TTTCGCCCGCGCCCTGCACGCGCACTCCGACCGCGCCGCGGGCCCCTTCGTGGCGGTGAACTGCGCGGCGCTGCCCGCCG
AGCTGATCGAGGCCGAGCTGTTCGGTGTCGAGAAAGGGGCCTACACCGGGGCCCATGCGGCGCGCGCCGGGCGCTTCGAG
CGCGCCGAAGGCGGCACGCTGTTCCTCGACGAGGTCGGCGACCTGCCGCTGGCGGCGCAGGCCAAGCTGCTGCGCGTGCT
GCAGGAGGGCGAGATCGAGCGGCTGGGGGCCGAGGCCACGCGCAAGGTCAACGTGCGCATGGTCACCGCGACCAACGTGG
ACCTGGAGGAAGCGGTGGCGCAGGGGCGATTCCGGCGCGACCTGCTGTACCGGCTCAACGTGTACCCCATCCGCATCCCG
CCGCTGCGCGAGCGCAGCGCCGACATCGAGCCGCTGGCGCGCCATCTGCTGGCGCGCTTCATGGCGGTGCACAACAAGCG
CCTCAGTGGCCTGGGCGAGCGCGCGCTGCAGGCGCTGATGCGGCACGACTGGCCTGGCAACGTGCGCGAGCTGGAGAACC
TGGTCGAGCGCGGTGTGATCCTGGCGGCCCAGGGCGGCACGGTGGAGCTCGAACACCTGTTCCCGAACCAGCCCCAGGAG
CGCCAGGATAGCGTGGACCCCCAGGGCCGGCTGGCCCGGGTCTTGCCTGCCCAAGAGAGCGAACTCTGCGAGCGCATCGT
GGGCAGCGGCCTGCCGCTCGAACAGCTCGAAGCCCAGGTGCTGGCGCTGGCGGTCGAGCGCAGCGGCGGCAACCTGTCGG
GTGCGGCACGCCTGCTGGGCCTGACGCGGCCGCAACTGGCCTACCGGCTCAAGCGCCAGCAACTGGACGAAGAAACCCCT
TGA

Upstream 100 bases:

>100_bases
ATGAAGGCTGTACCGAACCTCTGCTGGCTTGCCGAAAAAGGCTTGTGCAGTGAAAATATCGAGAATCCGCGCAAACACAG
CCCAGCGACCAGGAGACCCC

Downstream 100 bases:

>100_bases
AACCCGCAACGGGACGAACCGCATGCTGCCCACTCACCACATCAACGACAGATCGGCCGGACCATTCAACCGGCTGGCGG
CCGAGACGCCCCGAACGCTC

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MEPHLNYPPDADLRKLLRFEPDSGAIWLGERRMVLLHTAALSALRRDLITSVGTDHARRLLTRMGYASGLHDAGFANKTR
GDCSLEDMFLVGPQLHMLEGAARVTPLHLKMDAAAGLFEGEFRWDDSWEAHAHRLAYGVVDEPACWILLGYASGYTSAFM
GKLILFKEIRCGACGDEHCHIVGKPIDEWPDGAAYGQYFEDDSLLDKMDALSQQVQALKTTLEPTTSGGMLVGNSPAFQQ
AHNLMQRAAQTQVTVLLTGETGVGKERFARALHAHSDRAAGPFVAVNCAALPAELIEAELFGVEKGAYTGAHAARAGRFE
RAEGGTLFLDEVGDLPLAAQAKLLRVLQEGEIERLGAEATRKVNVRMVTATNVDLEEAVAQGRFRRDLLYRLNVYPIRIP
PLRERSADIEPLARHLLARFMAVHNKRLSGLGERALQALMRHDWPGNVRELENLVERGVILAAQGGTVELEHLFPNQPQE
RQDSVDPQGRLARVLPAQESELCERIVGSGLPLEQLEAQVLALAVERSGGNLSGAARLLGLTRPQLAYRLKRQQLDEETP

Sequences:

>Translated_560_residues
MEPHLNYPPDADLRKLLRFEPDSGAIWLGERRMVLLHTAALSALRRDLITSVGTDHARRLLTRMGYASGLHDAGFANKTR
GDCSLEDMFLVGPQLHMLEGAARVTPLHLKMDAAAGLFEGEFRWDDSWEAHAHRLAYGVVDEPACWILLGYASGYTSAFM
GKLILFKEIRCGACGDEHCHIVGKPIDEWPDGAAYGQYFEDDSLLDKMDALSQQVQALKTTLEPTTSGGMLVGNSPAFQQ
AHNLMQRAAQTQVTVLLTGETGVGKERFARALHAHSDRAAGPFVAVNCAALPAELIEAELFGVEKGAYTGAHAARAGRFE
RAEGGTLFLDEVGDLPLAAQAKLLRVLQEGEIERLGAEATRKVNVRMVTATNVDLEEAVAQGRFRRDLLYRLNVYPIRIP
PLRERSADIEPLARHLLARFMAVHNKRLSGLGERALQALMRHDWPGNVRELENLVERGVILAAQGGTVELEHLFPNQPQE
RQDSVDPQGRLARVLPAQESELCERIVGSGLPLEQLEAQVLALAVERSGGNLSGAARLLGLTRPQLAYRLKRQQLDEETP
>Mature_560_residues
MEPHLNYPPDADLRKLLRFEPDSGAIWLGERRMVLLHTAALSALRRDLITSVGTDHARRLLTRMGYASGLHDAGFANKTR
GDCSLEDMFLVGPQLHMLEGAARVTPLHLKMDAAAGLFEGEFRWDDSWEAHAHRLAYGVVDEPACWILLGYASGYTSAFM
GKLILFKEIRCGACGDEHCHIVGKPIDEWPDGAAYGQYFEDDSLLDKMDALSQQVQALKTTLEPTTSGGMLVGNSPAFQQ
AHNLMQRAAQTQVTVLLTGETGVGKERFARALHAHSDRAAGPFVAVNCAALPAELIEAELFGVEKGAYTGAHAARAGRFE
RAEGGTLFLDEVGDLPLAAQAKLLRVLQEGEIERLGAEATRKVNVRMVTATNVDLEEAVAQGRFRRDLLYRLNVYPIRIP
PLRERSADIEPLARHLLARFMAVHNKRLSGLGERALQALMRHDWPGNVRELENLVERGVILAAQGGTVELEHLFPNQPQE
RQDSVDPQGRLARVLPAQESELCERIVGSGLPLEQLEAQVLALAVERSGGNLSGAARLLGLTRPQLAYRLKRQQLDEETP

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=350, Percent_Identity=40.8571428571429, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI87082117, Length=426, Percent_Identity=39.906103286385, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790437, Length=328, Percent_Identity=43.9024390243902, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1790299, Length=338, Percent_Identity=44.6745562130178, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI1789087, Length=360, Percent_Identity=40.8333333333333, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1788905, Length=326, Percent_Identity=39.8773006134969, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1789233, Length=330, Percent_Identity=40.3030303030303, Blast_Score=225, Evalue=7e-60,
Organism=Escherichia coli, GI1786524, Length=379, Percent_Identity=37.467018469657, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI87082152, Length=237, Percent_Identity=48.5232067510549, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI87081872, Length=339, Percent_Identity=40.4129793510324, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787583, Length=235, Percent_Identity=39.1489361702128, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI87081858, Length=315, Percent_Identity=31.7460317460317, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789828, Length=271, Percent_Identity=33.210332103321, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 61615; Mature: 61615

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPHLNYPPDADLRKLLRFEPDSGAIWLGERRMVLLHTAALSALRRDLITSVGTDHARRL
CCCCCCCCCCHHHHHHHHCCCCCCCEEECCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHH
LTRMGYASGLHDAGFANKTRGDCSLEDMFLVGPQLHMLEGAARVTPLHLKMDAAAGLFEG
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCEEEEEEECCCCCCCCC
EFRWDDSWEAHAHRLAYGVVDEPACWILLGYASGYTSAFMGKLILFKEIRCGACGDEHCH
CCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCE
IVGKPIDEWPDGAAYGQYFEDDSLLDKMDALSQQVQALKTTLEPTTSGGMLVGNSPAFQQ
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHH
AHNLMQRAAQTQVTVLLTGETGVGKERFARALHAHSDRAAGPFVAVNCAALPAELIEAEL
HHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHCCHHHHHHHH
FGVEKGAYTGAHAARAGRFERAEGGTLFLDEVGDLPLAAQAKLLRVLQEGEIERLGAEAT
HCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHCCHHH
RKVNVRMVTATNVDLEEAVAQGRFRRDLLYRLNVYPIRIPPLRERSADIEPLARHLLARF
EEEEEEEEEECCCCHHHHHHHCHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHH
MAVHNKRLSGLGERALQALMRHDWPGNVRELENLVERGVILAAQGGTVELEHLFPNQPQE
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCH
RQDSVDPQGRLARVLPAQESELCERIVGSGLPLEQLEAQVLALAVERSGGNLSGAARLLG
HHCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHH
LTRPQLAYRLKRQQLDEETP
CCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEPHLNYPPDADLRKLLRFEPDSGAIWLGERRMVLLHTAALSALRRDLITSVGTDHARRL
CCCCCCCCCCHHHHHHHHCCCCCCCEEECCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHH
LTRMGYASGLHDAGFANKTRGDCSLEDMFLVGPQLHMLEGAARVTPLHLKMDAAAGLFEG
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCEEEEEEECCCCCCCCC
EFRWDDSWEAHAHRLAYGVVDEPACWILLGYASGYTSAFMGKLILFKEIRCGACGDEHCH
CCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCE
IVGKPIDEWPDGAAYGQYFEDDSLLDKMDALSQQVQALKTTLEPTTSGGMLVGNSPAFQQ
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHH
AHNLMQRAAQTQVTVLLTGETGVGKERFARALHAHSDRAAGPFVAVNCAALPAELIEAEL
HHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHCCHHHHHHHH
FGVEKGAYTGAHAARAGRFERAEGGTLFLDEVGDLPLAAQAKLLRVLQEGEIERLGAEAT
HCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHCCHHH
RKVNVRMVTATNVDLEEAVAQGRFRRDLLYRLNVYPIRIPPLRERSADIEPLARHLLARF
EEEEEEEEEECCCCHHHHHHHCHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHH
MAVHNKRLSGLGERALQALMRHDWPGNVRELENLVERGVILAAQGGTVELEHLFPNQPQE
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCH
RQDSVDPQGRLARVLPAQESELCERIVGSGLPLEQLEAQVLALAVERSGGNLSGAARLLG
HHCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHH
LTRPQLAYRLKRQQLDEETP
CCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]