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The map label for this gene is yfbQ [H]

Identifier: 121609616

GI number: 121609616

Start: 3004239

End: 3005468

Strand: Direct

Name: yfbQ [H]

Synonym: Veis_2662

Alternate gene names: 121609616

Gene position: 3004239-3005468 (Clockwise)

Preceding gene: 121609614

Following gene: 121609617

Centisome position: 53.97

GC content: 64.72

Gene sequence:

>1230_bases
ATGAAAGTCGTCCACAAATCCGCCAAGCTCGCCAACGTTTGCTACGACATTCGCGGTCCGATCATGGACGCGGCCAAGCA
GATGGAGGAAGACGGGCACAAGATCATCAAGCTGAACATCGGCAACCTGGCCGTGTTCGGCTTCGATGCCCCCGAGGAAA
TCCAGCTCGACATGATCCGCAACCTGCCCCATTCCTCGGGCTATTCGGACAGCAAGGGCATTTTCGCGGCGCGCAAGGCG
GTGATGCACGAGACGCAAAAGCAGGGCCTGGCGGGGGTCACGCTCGACGACATCTACCTGGGCAATGGCGCCAGCGAACT
CATCGTGATGGCCACCAATGCGCTGCTCGACGCCGGCGACGAACTGCTGCTGCCCGCGCCCGATTACCCGCTGTGGACGG
CCGCCGCCAGCCTCTCGGGCGGCACGCCGGTGCATTACCTGTGCGACGAGGCCCGGGGCTGGATGCCGGACCTCGACGAC
ATCCGCGCCAAAATCAGCCCCCGCACCAAGGGCATCGTGGTCATCAACCCGAACAACCCCACCGGAGCGCTGTACCCGGA
GTCGCTGCTCGAAGACCTGGTGCAGATCGCGCGCACCCATGGCCTGGTGATCTTCGCCGACGAGGTCTACGACAAGGTGC
TGTACGACGGCGCCAGGCACCGGGCCATCGGTTCATTGAGCCAGGATGTGCTGACGCTGACGTTCAACTCGCTGTCCAAG
AGCTACCGCTCCTGCGGCTACCGCGCCGGCTGGCTGGTGGTCTCGGGCGACAAGAAGCCGGCGCGCGACTACATCGAGGG
TCTGAACATGCTCTCGAACATGCGGCTGTGCTCGAACGTGCCCGGCCAATGGGCGATACAGACGGCCCTGGGGGGCTTTC
AGAGCATCAACGAGTTGGTCGGCGAAGGCGGGCGCCTGCGCCGGCAGCGCGACCTGGCGTATGAGCTGATCACGGCGATT
CCGGGCGTGAGCTGCGTCAAGCCGAGCGCGGCGCTGTACATGTTCGCGCGCCTCGACCCGGCCCTGTACCCGATCGCCGA
CGATCAGCAGTTCTTCCTGGAACTGCTGCAAGAGACCAAGGTGATGCTGGTCCAGGGCACGGGCTTCAACTGGCCGACGC
CGGACCATTTCCGCATCGTGTTCCTGCCGCATGAGGATGACCTGCGCGAGGCCATCGGCCGCGTGGCGCGGTTCCTCGCG
CAGTACCGCAAGCAGTGGGAGCGAATGTAG

Upstream 100 bases:

>100_bases
GCGCCGGAACCGCTGCTGATCTGTGGTCAAATTATAGGCATCGCCCGGGTGCCCGAAACCTGCCCCTGACTGCTGCCCCA
TCGCCCACCACTGCCAGCGC

Downstream 100 bases:

>100_bases
CGCCCGCATGTGGCGCTCGAGGATGCGGCGCGCATCTCCCGGCGCAGGCTCCGGCGGCCGGCCCGCGAGGGGCCAGGCCC
CCTTTTTCAAAAACCGATAA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MKVVHKSAKLANVCYDIRGPIMDAAKQMEEDGHKIIKLNIGNLAVFGFDAPEEIQLDMIRNLPHSSGYSDSKGIFAARKA
VMHETQKQGLAGVTLDDIYLGNGASELIVMATNALLDAGDELLLPAPDYPLWTAAASLSGGTPVHYLCDEARGWMPDLDD
IRAKISPRTKGIVVINPNNPTGALYPESLLEDLVQIARTHGLVIFADEVYDKVLYDGARHRAIGSLSQDVLTLTFNSLSK
SYRSCGYRAGWLVVSGDKKPARDYIEGLNMLSNMRLCSNVPGQWAIQTALGGFQSINELVGEGGRLRRQRDLAYELITAI
PGVSCVKPSAALYMFARLDPALYPIADDQQFFLELLQETKVMLVQGTGFNWPTPDHFRIVFLPHEDDLREAIGRVARFLA
QYRKQWERM

Sequences:

>Translated_409_residues
MKVVHKSAKLANVCYDIRGPIMDAAKQMEEDGHKIIKLNIGNLAVFGFDAPEEIQLDMIRNLPHSSGYSDSKGIFAARKA
VMHETQKQGLAGVTLDDIYLGNGASELIVMATNALLDAGDELLLPAPDYPLWTAAASLSGGTPVHYLCDEARGWMPDLDD
IRAKISPRTKGIVVINPNNPTGALYPESLLEDLVQIARTHGLVIFADEVYDKVLYDGARHRAIGSLSQDVLTLTFNSLSK
SYRSCGYRAGWLVVSGDKKPARDYIEGLNMLSNMRLCSNVPGQWAIQTALGGFQSINELVGEGGRLRRQRDLAYELITAI
PGVSCVKPSAALYMFARLDPALYPIADDQQFFLELLQETKVMLVQGTGFNWPTPDHFRIVFLPHEDDLREAIGRVARFLA
QYRKQWERM
>Mature_409_residues
MKVVHKSAKLANVCYDIRGPIMDAAKQMEEDGHKIIKLNIGNLAVFGFDAPEEIQLDMIRNLPHSSGYSDSKGIFAARKA
VMHETQKQGLAGVTLDDIYLGNGASELIVMATNALLDAGDELLLPAPDYPLWTAAASLSGGTPVHYLCDEARGWMPDLDD
IRAKISPRTKGIVVINPNNPTGALYPESLLEDLVQIARTHGLVIFADEVYDKVLYDGARHRAIGSLSQDVLTLTFNSLSK
SYRSCGYRAGWLVVSGDKKPARDYIEGLNMLSNMRLCSNVPGQWAIQTALGGFQSINELVGEGGRLRRQRDLAYELITAI
PGVSCVKPSAALYMFARLDPALYPIADDQQFFLELLQETKVMLVQGTGFNWPTPDHFRIVFLPHEDDLREAIGRVARFLA
QYRKQWERM

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=471, Percent_Identity=27.6008492569002, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI215599424, Length=377, Percent_Identity=29.4429708222812, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4507369, Length=392, Percent_Identity=27.2959183673469, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI4885351, Length=478, Percent_Identity=27.8242677824268, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI95147551, Length=170, Percent_Identity=28.8235294117647, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI169881279, Length=170, Percent_Identity=28.8235294117647, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI56713254, Length=167, Percent_Identity=25.748502994012, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI56713256, Length=167, Percent_Identity=25.748502994012, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI169881281, Length=156, Percent_Identity=27.5641025641026, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=62.3762376237624, Blast_Score=549, Evalue=1e-157,
Organism=Escherichia coli, GI1788722, Length=391, Percent_Identity=26.5984654731458, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786816, Length=371, Percent_Identity=24.7978436657682, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17567663, Length=410, Percent_Identity=28.780487804878, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=477, Percent_Identity=24.5283018867925, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=233, Percent_Identity=30.0429184549356, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=233, Percent_Identity=30.0429184549356, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=165, Percent_Identity=27.8787878787879, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=295, Percent_Identity=25.0847457627119, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=381, Percent_Identity=28.8713910761155, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6323118, Length=380, Percent_Identity=28.4210526315789, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322401, Length=282, Percent_Identity=25.531914893617, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI18859735, Length=414, Percent_Identity=28.5024154589372, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24641770, Length=465, Percent_Identity=25.1612903225806, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24641760, Length=465, Percent_Identity=25.1612903225806, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24641768, Length=465, Percent_Identity=25.1612903225806, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24641766, Length=465, Percent_Identity=25.1612903225806, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24641764, Length=465, Percent_Identity=25.1612903225806, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI45551451, Length=465, Percent_Identity=25.1612903225806, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573069, Length=175, Percent_Identity=27.4285714285714, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646114, Length=175, Percent_Identity=27.4285714285714, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573067, Length=175, Percent_Identity=27.4285714285714, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573065, Length=175, Percent_Identity=27.4285714285714, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45311; Mature: 45311

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVHKSAKLANVCYDIRGPIMDAAKQMEEDGHKIIKLNIGNLAVFGFDAPEEIQLDMIR
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCEEEEECCCCCHHHHHHHH
NLPHSSGYSDSKGIFAARKAVMHETQKQGLAGVTLDDIYLGNGASELIVMATNALLDAGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHEEECCCCCCEEEEEHHHHHCCCC
ELLLPAPDYPLWTAAASLSGGTPVHYLCDEARGWMPDLDDIRAKISPRTKGIVVINPNNP
CEEECCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGALYPESLLEDLVQIARTHGLVIFADEVYDKVLYDGARHRAIGSLSQDVLTLTFNSLSK
CCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SYRSCGYRAGWLVVSGDKKPARDYIEGLNMLSNMRLCSNVPGQWAIQTALGGFQSINELV
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCEEHHHHHHHHHHHHHHH
GEGGRLRRQRDLAYELITAIPGVSCVKPSAALYMFARLDPALYPIADDQQFFLELLQETK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHCCCCCCCCCCCHHHHHHHHHCCC
VMLVQGTGFNWPTPDHFRIVFLPHEDDLREAIGRVARFLAQYRKQWERM
EEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVVHKSAKLANVCYDIRGPIMDAAKQMEEDGHKIIKLNIGNLAVFGFDAPEEIQLDMIR
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCEEEEECCCCCHHHHHHHH
NLPHSSGYSDSKGIFAARKAVMHETQKQGLAGVTLDDIYLGNGASELIVMATNALLDAGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHEEECCCCCCEEEEEHHHHHCCCC
ELLLPAPDYPLWTAAASLSGGTPVHYLCDEARGWMPDLDDIRAKISPRTKGIVVINPNNP
CEEECCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGALYPESLLEDLVQIARTHGLVIFADEVYDKVLYDGARHRAIGSLSQDVLTLTFNSLSK
CCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SYRSCGYRAGWLVVSGDKKPARDYIEGLNMLSNMRLCSNVPGQWAIQTALGGFQSINELV
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCEEHHHHHHHHHHHHHHH
GEGGRLRRQRDLAYELITAIPGVSCVKPSAALYMFARLDPALYPIADDQQFFLELLQETK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHCCCCCCCCCCCHHHHHHHHHCCC
VMLVQGTGFNWPTPDHFRIVFLPHEDDLREAIGRVARFLAQYRKQWERM
EEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]