Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 121609504

GI number: 121609504

Start: 2878957

End: 2879352

Strand: Direct

Name: acpS

Synonym: Veis_2548

Alternate gene names: 121609504

Gene position: 2878957-2879352 (Clockwise)

Preceding gene: 121609503

Following gene: 121609505

Centisome position: 51.72

GC content: 61.62

Gene sequence:

>396_bases
ATGCATATCGGAATCGACATAGTCGAAGTGCCGCGGATTGCGAAGGCGCTGAACCGGGGTGACAAGGGCTTTCTGAACGC
GGTCTACACGGCCGGGGAAGCTGCTCACATCGAGCAAGCTCACGCCGGTGACGTGCGCGCTGCCGGCATATGGGCCGCCA
AGGAGGCAGTCGTCAAGGCCTTCGGGGTCGGATTTTCCGAAGGCGTAACCTTCCGCGATGTGGAGGTGCGATACACCGCC
ACCGGTCAACCCCAGGCCGTCTTGTCGGGCAAGCTCGCTTCTTTGGCCGTGGACCGATCCCTGCAAGTGCTGTCCATCAG
CATTTCCCACACTGAGAATTACGCAGCAGCGACGGCTTTGGTCGGGCCGGTATCGGCTGAGGTGCGACCCGTATGA

Upstream 100 bases:

>100_bases
CCGTGCTGACCTCGAACTTCCGTGACGCCTCGCAACTCGTCGCTGAATTCCCTGCGCGCATGCCGATTTCTGAGCGGATC
GATCTGGTCAGGCCATAGTG

Downstream 100 bases:

>100_bases
CGCTACTCGTCTCGGACTTGTGGACGATGAATGATTTCCCTGGCAGATCAAGCAGCGAGGTGCTGACCGGTTGCCGCACT
GGCCTGCGGCATGGCAGTCT

Product: holo-acyl-carrier-protein synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MHIGIDIVEVPRIAKALNRGDKGFLNAVYTAGEAAHIEQAHAGDVRAAGIWAAKEAVVKAFGVGFSEGVTFRDVEVRYTA
TGQPQAVLSGKLASLAVDRSLQVLSISISHTENYAAATALVGPVSAEVRPV

Sequences:

>Translated_131_residues
MHIGIDIVEVPRIAKALNRGDKGFLNAVYTAGEAAHIEQAHAGDVRAAGIWAAKEAVVKAFGVGFSEGVTFRDVEVRYTA
TGQPQAVLSGKLASLAVDRSLQVLSISISHTENYAAATALVGPVSAEVRPV
>Mature_131_residues
MHIGIDIVEVPRIAKALNRGDKGFLNAVYTAGEAAHIEQAHAGDVRAAGIWAAKEAVVKAFGVGFSEGVTFRDVEVRYTA
TGQPQAVLSGKLASLAVDRSLQVLSISISHTENYAAATALVGPVSAEVRPV

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_VEREI (A1WKY6)

Other databases:

- EMBL:   CP000542
- RefSeq:   YP_997311.1
- ProteinModelPortal:   A1WKY6
- SMR:   A1WKY6
- STRING:   A1WKY6
- GeneID:   4690370
- GenomeReviews:   CP000542_GR
- KEGG:   vei:Veis_2548
- NMPDR:   fig|391735.5.peg.2398
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   SISHTEN
- ProtClustDB:   CLSK701257
- BioCyc:   VEIS391735:VEIS_2548-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13667; Mature: 13667

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIGIDIVEVPRIAKALNRGDKGFLNAVYTAGEAAHIEQAHAGDVRAAGIWAAKEAVVKA
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHCCCCCCCCCEEHHHHHHHHHHHHH
FGVGFSEGVTFRDVEVRYTATGQPQAVLSGKLASLAVDRSLQVLSISISHTENYAAATAL
HCCCCCCCCEEEEEEEEEEECCCCHHHHHCHHHHHHHCCCEEEEEEEECCCCCHHHHHHE
VGPVSAEVRPV
ECCCCCCEECC
>Mature Secondary Structure
MHIGIDIVEVPRIAKALNRGDKGFLNAVYTAGEAAHIEQAHAGDVRAAGIWAAKEAVVKA
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHCCCCCCCCCEEHHHHHHHHHHHHH
FGVGFSEGVTFRDVEVRYTATGQPQAVLSGKLASLAVDRSLQVLSISISHTENYAAATAL
HCCCCCCCCEEEEEEEEEEECCCCHHHHHCHHHHHHHCCCEEEEEEEECCCCCHHHHHHE
VGPVSAEVRPV
ECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA