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The map label for this gene is baeC [H]

Identifier: 121609502

GI number: 121609502

Start: 2876946

End: 2877893

Strand: Direct

Name: baeC [H]

Synonym: Veis_2546

Alternate gene names: 121609502

Gene position: 2876946-2877893 (Clockwise)

Preceding gene: 121609501

Following gene: 121609503

Centisome position: 51.68

GC content: 64.14

Gene sequence:

>948_bases
ATGTTCACTGGCCAAGGGGCCCAGCGGGTCGGGATGGGTTCGGACGTGGATGAAGCAGCGAAAAGCAAGGCGGTCTGGGA
CTGTGCTTGCGACATCTCCGGGTTCGACGTCCGCCGCATGTGCTGGAAAGGCCCGATGGGCAAGCTCTCGGAGACCCGGT
ACCAGCAAGTCGCGGTGACCGCAGTCAACCTCGCGAGCTACTACGCACTGAAGGCTTCACGCCTGCTGCCGGAGGACTCG
GTCTTCATCGGCCACAGCGTCGGCGAGTACTCGGCACTACACGCAAGCGGGGCGCTCGACTTGGAGCAGACCTTCAAGGC
CGTGAACGCACGCGCGATCGGCATGCAGACGCAGGCCGAGCAGACCAAGGGGGCGATGTATGCGGTCAAGGGCGGCTCGA
TCGTTCAGGTCAACGACGTCATCGACGCTATGGGGTTGCACGGGCAAGTAGTGATCGCCAATGACAACTCGCCACTCCAA
GTGGTCATCGCGGGCAACTCGGGCATTGTGAAGCAGGTGGGCGCGGAGCTCTCGGGGCGTCGCCTCCCGACAGTCAGGCT
CGCGGTGAATGGCGCCTGGCATAGCCCGCTGATGGCCGGGATGCTGCCGGAATACGGCAGCCTGCTGAGGAGCCTGGACA
TCAGGATGCCTTCGTCGCAGATTCTTATGAACCGCTCGGCGCAGGAGCCGCTGTCCCCGCAAGAGATCCGGGACAACCTG
ACTTACCATGTCGTGGAGACGGTCCGGTGGCGGGAGACCGTCGAGAAACTGCTTCAGCGCAACAAGGCCCGCTTCCTGGA
GGTGGGGCCGCGCAAGGTGCTTTGCGCGCTAGTGTCAGATTGCGGCAGCCTGGGCTCCCAGGCGCAGACTACCCATTGCA
GCCAGATGCTGAGGAGCTTGCCCAGTCACCTGCCCGCGCCACGCTTGCAAGAGGCCCCCGCATGCTGA

Upstream 100 bases:

>100_bases
ACGCAGTGAATTCGGACGGTTCGGGCAGTCGCCCTTGCTATATTTCGGGCTGAAATTCTCTCTATGAACAAGGGAGGCAC
TTGTGGATTCATGGGTTGTG

Downstream 100 bases:

>100_bases
CTTCATTCGGACGATATCGGCTCAGCTACGCTGTCAGCCTCTTCCTCGCTATCTCCATCCTCGGCGCCTTGCTAATGTTC
GGGTTCGCCAGGAATGCCGG

Product: acyl transferase domain-containing protein

Products: NA

Alternate protein names: AT [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MFTGQGAQRVGMGSDVDEAAKSKAVWDCACDISGFDVRRMCWKGPMGKLSETRYQQVAVTAVNLASYYALKASRLLPEDS
VFIGHSVGEYSALHASGALDLEQTFKAVNARAIGMQTQAEQTKGAMYAVKGGSIVQVNDVIDAMGLHGQVVIANDNSPLQ
VVIAGNSGIVKQVGAELSGRRLPTVRLAVNGAWHSPLMAGMLPEYGSLLRSLDIRMPSSQILMNRSAQEPLSPQEIRDNL
TYHVVETVRWRETVEKLLQRNKARFLEVGPRKVLCALVSDCGSLGSQAQTTHCSQMLRSLPSHLPAPRLQEAPAC

Sequences:

>Translated_315_residues
MFTGQGAQRVGMGSDVDEAAKSKAVWDCACDISGFDVRRMCWKGPMGKLSETRYQQVAVTAVNLASYYALKASRLLPEDS
VFIGHSVGEYSALHASGALDLEQTFKAVNARAIGMQTQAEQTKGAMYAVKGGSIVQVNDVIDAMGLHGQVVIANDNSPLQ
VVIAGNSGIVKQVGAELSGRRLPTVRLAVNGAWHSPLMAGMLPEYGSLLRSLDIRMPSSQILMNRSAQEPLSPQEIRDNL
TYHVVETVRWRETVEKLLQRNKARFLEVGPRKVLCALVSDCGSLGSQAQTTHCSQMLRSLPSHLPAPRLQEAPAC
>Mature_315_residues
MFTGQGAQRVGMGSDVDEAAKSKAVWDCACDISGFDVRRMCWKGPMGKLSETRYQQVAVTAVNLASYYALKASRLLPEDS
VFIGHSVGEYSALHASGALDLEQTFKAVNARAIGMQTQAEQTKGAMYAVKGGSIVQVNDVIDAMGLHGQVVIANDNSPLQ
VVIAGNSGIVKQVGAELSGRRLPTVRLAVNGAWHSPLMAGMLPEYGSLLRSLDIRMPSSQILMNRSAQEPLSPQEIRDNL
TYHVVETVRWRETVEKLLQRNKARFLEVGPRKVLCALVSDCGSLGSQAQTTHCSQMLRSLPSHLPAPRLQEAPAC

Specific function: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the transfer of the malonyl-CoA group to the acyl-carrier-protein AcpK (Mal-AcpK) [H]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=300, Percent_Identity=28.3333333333333, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1787334, Length=282, Percent_Identity=29.4326241134752, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71984332, Length=297, Percent_Identity=27.9461279461279, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24665753, Length=305, Percent_Identity=26.5573770491803, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34077; Mature: 34077

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGQGAQRVGMGSDVDEAAKSKAVWDCACDISGFDVRRMCWKGPMGKLSETRYQQVAVT
CCCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHH
AVNLASYYALKASRLLPEDSVFIGHSVGEYSALHASGALDLEQTFKAVNARAIGMQTQAE
HHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHH
QTKGAMYAVKGGSIVQVNDVIDAMGLHGQVVIANDNSPLQVVIAGNSGIVKQVGAELSGR
HHCCCEEEECCCCEEEHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHCCC
RLPTVRLAVNGAWHSPLMAGMLPEYGSLLRSLDIRMPSSQILMNRSAQEPLSPQEIRDNL
CCCEEEEEECCCCCCHHHHHHCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHCCC
TYHVVETVRWRETVEKLLQRNKARFLEVGPRKVLCALVSDCGSLGSQAQTTHCSQMLRSL
HHHHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
PSHLPAPRLQEAPAC
HHHCCCCCCCCCCCC
>Mature Secondary Structure
MFTGQGAQRVGMGSDVDEAAKSKAVWDCACDISGFDVRRMCWKGPMGKLSETRYQQVAVT
CCCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHH
AVNLASYYALKASRLLPEDSVFIGHSVGEYSALHASGALDLEQTFKAVNARAIGMQTQAE
HHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHH
QTKGAMYAVKGGSIVQVNDVIDAMGLHGQVVIANDNSPLQVVIAGNSGIVKQVGAELSGR
HHCCCEEEECCCCEEEHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHCCC
RLPTVRLAVNGAWHSPLMAGMLPEYGSLLRSLDIRMPSSQILMNRSAQEPLSPQEIRDNL
CCCEEEEEECCCCCCHHHHHHCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHCCC
TYHVVETVRWRETVEKLLQRNKARFLEVGPRKVLCALVSDCGSLGSQAQTTHCSQMLRSL
HHHHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
PSHLPAPRLQEAPAC
HHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA