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The map label for this gene is ilvE [H]

Identifier: 121609431

GI number: 121609431

Start: 2808828

End: 2809769

Strand: Direct

Name: ilvE [H]

Synonym: Veis_2475

Alternate gene names: 121609431

Gene position: 2808828-2809769 (Clockwise)

Preceding gene: 121609430

Following gene: 121609432

Centisome position: 50.46

GC content: 62.95

Gene sequence:

>942_bases
ATGAGCCCCGTAGTTCCCTCGATGGCCGATCGTGACGGCAAGATCTGGATGGACGGCCAGATGGTCGATTGGCGCGATGC
CAAGGTCCATGTGCTGACCCACACCCTGCATTACGGCTGCGGCGCCTTCGAGGGCCTGCGCGCCTACAAGACGGCCGACG
GCACGACCGCCATCTTCCGCCTGCATGAGCACACCGAGCGGCTGTTCAACAGCACAAAAATCCTGCGCATGCAACTGCCG
TTCAGCCGCGATGAGGTGAACCAGGCGCAACGGGCGGTGGTGCGGGAGAACCGGCTCGACGCCTGTTACCTGCGGCCATT
GGCTTGGATCGGCTCGCAAAAACTGGGGGTCTCGCCCAAGGGCAACCAGATCCATTTGATGGTGGCGGCCTGGGCCTGGG
GCGCCTACCTGGGCGAGGAGGGCATGCGGCGCGGCATCCGCGTCAAGACCAGCAGCTACACGCGCCACCATGTGAACATC
ACGATGACGCAGGCCAAGGCGGTGAGCAATTACACCAACTCCATCCTGGCCAACATGGAGGCCGTCGATGATGGTTACGA
CGAGGCGCTGCTGCTCGACAGCACGGGCTTTGTCAGCGAAGGCGCCGGCGAGAATGTGTTCGTGGTCAAGGACGGCGTGA
TCTACACCCCCGATCTGTCGGCCGGCGCGCTCAATGGCATCACCCGCAACACGGTGTTCCATATCGCCAAGGATCTGGGG
CTGGAGATCGTCCCAAAGCGCATCACGCGCGACGAGATCTACATCGCTGACGAGGCTTTCTTCACCGGCACGGCGGCCGA
GGTGACGCCGATCCGCGAGCTCGATCGGATAGAGATCGGCAGCGGCAGCCGGGGCCCTGTCACCGAAAAGATCCAGGGCG
CTTTCTTTGACATCGTCAACGGCCGCAATGCCCATTACGCCCATTGGCTCACCAAGGTCTGA

Upstream 100 bases:

>100_bases
CTGGGTCTTGTTCCGGCCGCAGGACGGCAACGCCAGCCCGCCGCCCGCTGCCCCGTAAAATTGCGCTTTTGCGCCCTGCA
AACCCGGCAAAGGAATATCC

Downstream 100 bases:

>100_bases
TGCCCATGCCGCAAGCCATCGTTGAACTGCCGGCCCGGGAACTGAACGCGCAGGGCGGCGTTTTTTGCCCCAACCCCCGG
GCCGACATGCCGTTGTGGAA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSPVVPSMADRDGKIWMDGQMVDWRDAKVHVLTHTLHYGCGAFEGLRAYKTADGTTAIFRLHEHTERLFNSTKILRMQLP
FSRDEVNQAQRAVVRENRLDACYLRPLAWIGSQKLGVSPKGNQIHLMVAAWAWGAYLGEEGMRRGIRVKTSSYTRHHVNI
TMTQAKAVSNYTNSILANMEAVDDGYDEALLLDSTGFVSEGAGENVFVVKDGVIYTPDLSAGALNGITRNTVFHIAKDLG
LEIVPKRITRDEIYIADEAFFTGTAAEVTPIRELDRIEIGSGSRGPVTEKIQGAFFDIVNGRNAHYAHWLTKV

Sequences:

>Translated_313_residues
MSPVVPSMADRDGKIWMDGQMVDWRDAKVHVLTHTLHYGCGAFEGLRAYKTADGTTAIFRLHEHTERLFNSTKILRMQLP
FSRDEVNQAQRAVVRENRLDACYLRPLAWIGSQKLGVSPKGNQIHLMVAAWAWGAYLGEEGMRRGIRVKTSSYTRHHVNI
TMTQAKAVSNYTNSILANMEAVDDGYDEALLLDSTGFVSEGAGENVFVVKDGVIYTPDLSAGALNGITRNTVFHIAKDLG
LEIVPKRITRDEIYIADEAFFTGTAAEVTPIRELDRIEIGSGSRGPVTEKIQGAFFDIVNGRNAHYAHWLTKV
>Mature_312_residues
SPVVPSMADRDGKIWMDGQMVDWRDAKVHVLTHTLHYGCGAFEGLRAYKTADGTTAIFRLHEHTERLFNSTKILRMQLPF
SRDEVNQAQRAVVRENRLDACYLRPLAWIGSQKLGVSPKGNQIHLMVAAWAWGAYLGEEGMRRGIRVKTSSYTRHHVNIT
MTQAKAVSNYTNSILANMEAVDDGYDEALLLDSTGFVSEGAGENVFVVKDGVIYTPDLSAGALNGITRNTVFHIAKDLGL
EIVPKRITRDEIYIADEAFFTGTAAEVTPIRELDRIEIGSGSRGPVTEKIQGAFFDIVNGRNAHYAHWLTKV

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=332, Percent_Identity=25.9036144578313, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI38176287, Length=314, Percent_Identity=25.796178343949, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI296010904, Length=314, Percent_Identity=25.796178343949, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI296010906, Length=314, Percent_Identity=25.796178343949, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI48994963, Length=300, Percent_Identity=46.3333333333333, Blast_Score=288, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17565728, Length=284, Percent_Identity=26.056338028169, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322608, Length=289, Percent_Identity=25.6055363321799, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322002, Length=310, Percent_Identity=26.1290322580645, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34825; Mature: 34694

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPVVPSMADRDGKIWMDGQMVDWRDAKVHVLTHTLHYGCGAFEGLRAYKTADGTTAIFR
CCCCCCCCCCCCCEEEECCEEECCCCCEEEEEEEEHHHCCCCHHHHHHEECCCCCEEEEE
LHEHTERLFNSTKILRMQLPFSRDEVNQAQRAVVRENRLDACYLRPLAWIGSQKLGVSPK
EHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCC
GNQIHLMVAAWAWGAYLGEEGMRRGIRVKTSSYTRHHVNITMTQAKAVSNYTNSILANME
CCEEEEEEEEEHHHHHHCHHHHHCCEEEEECCCEEEEEEEEEEHHHHHHHHHHHHHHHHH
AVDDGYDEALLLDSTGFVSEGAGENVFVVKDGVIYTPDLSAGALNGITRNTVFHIAKDLG
HHCCCCCCEEEEECCCCCCCCCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHCC
LEIVPKRITRDEIYIADEAFFTGTAAEVTPIRELDRIEIGSGSRGPVTEKIQGAFFDIVN
CEEECCCCCCCEEEEECCCEECCCCCCCCCHHHCCEEEECCCCCCCCHHHHCCCEEEEEC
GRNAHYAHWLTKV
CCCCEEHHHEECC
>Mature Secondary Structure 
SPVVPSMADRDGKIWMDGQMVDWRDAKVHVLTHTLHYGCGAFEGLRAYKTADGTTAIFR
CCCCCCCCCCCCEEEECCEEECCCCCEEEEEEEEHHHCCCCHHHHHHEECCCCCEEEEE
LHEHTERLFNSTKILRMQLPFSRDEVNQAQRAVVRENRLDACYLRPLAWIGSQKLGVSPK
EHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCC
GNQIHLMVAAWAWGAYLGEEGMRRGIRVKTSSYTRHHVNITMTQAKAVSNYTNSILANME
CCEEEEEEEEEHHHHHHCHHHHHCCEEEEECCCEEEEEEEEEEHHHHHHHHHHHHHHHHH
AVDDGYDEALLLDSTGFVSEGAGENVFVVKDGVIYTPDLSAGALNGITRNTVFHIAKDLG
HHCCCCCCEEEEECCCCCCCCCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHCC
LEIVPKRITRDEIYIADEAFFTGTAAEVTPIRELDRIEIGSGSRGPVTEKIQGAFFDIVN
CEEECCCCCCCEEEEECCCEECCCCCCCCCHHHCCEEEECCCCCCCCHHHHCCCEEEEEC
GRNAHYAHWLTKV
CCCCEEHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]