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The map label for this gene is ygbM [C]

Identifier: 121609418

GI number: 121609418

Start: 2796818

End: 2797618

Strand: Direct

Name: ygbM [C]

Synonym: Veis_2462

Alternate gene names: 121609418

Gene position: 2796818-2797618 (Clockwise)

Preceding gene: 121609417

Following gene: 121609421

Centisome position: 50.24

GC content: 66.79

Gene sequence:

>801_bases
ATGCCCCGCTTTGCCGCCAACCTCTCGATGCTCTACAACGAGGTAGAGTTTTTGCACCGCTTTGCCGCCGCTGCCGACGA
TGGTTTCAAGGCGGTGGAATACCTGTTTCCCTACAGCCACCCCGCGCAAGAACTGGCTGCGCGCCTGCGCGCCCACGGCT
TGCAGCAGGTGCTCTTCAATGCCCCGGCCGGCCGCTGGGACGCTGGCGAGCGCGGCCTGGCCTGCCTGCCAGGGCGCCAG
GCCGAGTTTCACGCAGCGCTGGAGCAGGCCCTGGCCTACGCCCAGGTGCTCGAATGCCCCCGCATCCATGTGATGGCCGG
CCTGGTGCCGCAGGGCGTGGACGCCGCCACCGTGCGCGCCACCTATGTCGCCAATCTGCGCCACGCTGCCAAGCAGGCCG
CGCCGCAGGGCATCGACATCCTGCTGGAGCCCATCAATGGCCGTGACATGCCCGGCTTCTTCCTGAGCCGCCAAGACCAG
GCCCATGCCTTGGTCGCCGAGATCGGTGCCGCCAACGTCAAGGTGCAGATGGACCTGTACCACGCCCAGATCGTCGAGGG
CGACCTGGCGACGAAGTTGCGCCAGTACCTGCCCACAGGCCGCATTGCCCATATCCAGATCGCCGGCGTGCCCGAGCGCC
ATGAACCGGACGTGGGCGAGATCAACCACAGCTACCTGTTCCAACTGCTCGACCAAGAGGGCTACGACGGCTGGATCGGC
TGCGAATACCGCCCCAGCCGTGGCGCTGTAGCGCAGGCCACGTCCGATGGACTGGGCTGGATCAGGCCCTGGTTGAAGTG
A

Upstream 100 bases:

>100_bases
GCCGCGCATTGCAGAACTGCGCCAGACCTTTGGCGCCCATCGGTAAACCATGTAAATCATGCAAACCATGTAAACCCCGC
AGACCACGGAAGACCCCCCC

Downstream 100 bases:

>100_bases
CGTCCTGAAGTGACACCCTGAAGCGACACCCATTGGCGCGGCGGTGCGCCGGCCGCCTTCCGTCATCGGGTATCGTTTTT
GCCGCTGCCCCGATGACTGC

Product: hydroxypyruvate isomerase

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MPRFAANLSMLYNEVEFLHRFAAAADDGFKAVEYLFPYSHPAQELAARLRAHGLQQVLFNAPAGRWDAGERGLACLPGRQ
AEFHAALEQALAYAQVLECPRIHVMAGLVPQGVDAATVRATYVANLRHAAKQAAPQGIDILLEPINGRDMPGFFLSRQDQ
AHALVAEIGAANVKVQMDLYHAQIVEGDLATKLRQYLPTGRIAHIQIAGVPERHEPDVGEINHSYLFQLLDQEGYDGWIG
CEYRPSRGAVAQATSDGLGWIRPWLK

Sequences:

>Translated_266_residues
MPRFAANLSMLYNEVEFLHRFAAAADDGFKAVEYLFPYSHPAQELAARLRAHGLQQVLFNAPAGRWDAGERGLACLPGRQ
AEFHAALEQALAYAQVLECPRIHVMAGLVPQGVDAATVRATYVANLRHAAKQAAPQGIDILLEPINGRDMPGFFLSRQDQ
AHALVAEIGAANVKVQMDLYHAQIVEGDLATKLRQYLPTGRIAHIQIAGVPERHEPDVGEINHSYLFQLLDQEGYDGWIG
CEYRPSRGAVAQATSDGLGWIRPWLK
>Mature_265_residues
PRFAANLSMLYNEVEFLHRFAAAADDGFKAVEYLFPYSHPAQELAARLRAHGLQQVLFNAPAGRWDAGERGLACLPGRQA
EFHAALEQALAYAQVLECPRIHVMAGLVPQGVDAATVRATYVANLRHAAKQAAPQGIDILLEPINGRDMPGFFLSRQDQA
HALVAEIGAANVKVQMDLYHAQIVEGDLATKLRQYLPTGRIAHIQIAGVPERHEPDVGEINHSYLFQLLDQEGYDGWIGC
EYRPSRGAVAQATSDGLGWIRPWLK

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=269, Percent_Identity=47.2118959107807, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI300068964, Length=245, Percent_Identity=47.3469387755102, Blast_Score=203, Evalue=1e-52,
Organism=Escherichia coli, GI1789095, Length=264, Percent_Identity=50, Blast_Score=259, Evalue=1e-70,
Organism=Escherichia coli, GI1786718, Length=264, Percent_Identity=43.9393939393939, Blast_Score=243, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17552022, Length=248, Percent_Identity=37.5, Blast_Score=167, Evalue=7e-42,
Organism=Drosophila melanogaster, GI17530883, Length=263, Percent_Identity=34.9809885931559, Blast_Score=165, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 29298; Mature: 29166

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAANLSMLYNEVEFLHRFAAAADDGFKAVEYLFPYSHPAQELAARLRAHGLQQVLFN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
APAGRWDAGERGLACLPGRQAEFHAALEQALAYAQVLECPRIHVMAGLVPQGVDAATVRA
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCHHEEHHCCCCCCCCHHHHHH
TYVANLRHAAKQAAPQGIDILLEPINGRDMPGFFLSRQDQAHALVAEIGAANVKVQMDLY
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHCCCCHHHHHHHHHCCCCEEEEEEEH
HAQIVEGDLATKLRQYLPTGRIAHIQIAGVPERHEPDVGEINHSYLFQLLDQEGYDGWIG
HHHHHCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEC
CEYRPSRGAVAQATSDGLGWIRPWLK
CEECCCCCCEECCCCCCCHHHHHHCC
>Mature Secondary Structure 
PRFAANLSMLYNEVEFLHRFAAAADDGFKAVEYLFPYSHPAQELAARLRAHGLQQVLFN
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
APAGRWDAGERGLACLPGRQAEFHAALEQALAYAQVLECPRIHVMAGLVPQGVDAATVRA
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCHHEEHHCCCCCCCCHHHHHH
TYVANLRHAAKQAAPQGIDILLEPINGRDMPGFFLSRQDQAHALVAEIGAANVKVQMDLY
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHCCCCHHHHHHHHHCCCCEEEEEEEH
HAQIVEGDLATKLRQYLPTGRIAHIQIAGVPERHEPDVGEINHSYLFQLLDQEGYDGWIG
HHHHHCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEC
CEYRPSRGAVAQATSDGLGWIRPWLK
CEECCCCCCEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]