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The map label for this gene is hpcG [H]

Identifier: 121609367

GI number: 121609367

Start: 2724867

End: 2725679

Strand: Direct

Name: hpcG [H]

Synonym: Veis_2410

Alternate gene names: 121609367

Gene position: 2724867-2725679 (Clockwise)

Preceding gene: 121609366

Following gene: 121609368

Centisome position: 48.95

GC content: 66.91

Gene sequence:

>813_bases
GTGAGCCTGGACCAGAACACCCTCGCCCAGGCCGCCGAGCGGTTGCAGCAGGCGCAGCGCACGCGCCTGGCCTGCCGCCA
GTTCTCGCTCGACTACCCGGAGATGACGATCGACGACGCCTACGCGATCCAGCACGCCTGGATGCAGCTCGAGCTGCGCA
ATGGCCGCACGATAAAAGGCCACAAGATTGGCCTCACGTCGAAGGCGATGCAGCGCGCGGTGAACATCGCCGAGCCGGAC
TACGGCACGCTGCTGGACGACATGTTCTACCGCGACGGCGCGGTGATCGAGTCGGAGCGCTTCCTGCAGTTGAAGATCGA
GGCCGAACTGGCCTTCGTGCTCGCCAAGCCGCTGGCTGGCCCCGACTGCACGCTGTTCGACGTGCTCGACGCCACCGCGT
ACATCACGCCCGCGCTGGAGATCCTCGACGCGCGCATCGAGCGCATCGACCCGCAAACCAGGCGCATGCGCACCGTGCTC
GACACCATCTCCGATAACGCGGCCAACGCCGCCTTGGTGCTGGGGGGACGCCCGTTCAGGCCGGCGGTGTCGGACGCCGA
CATGCGACGCATCGGCGCCATCGTCAGCCGCAACGGCGAGGTCGAAGAAACCGGCCTGGCCGCCGGGGTGCTCAATCACC
CCGGCTATGGCGTGGCGTGGCTCGCCAATCGGCTGCATCGTTTTGGCGTGACCTTGCAGCCCAGGCAGGTCATCCTGGCG
GGCTCGTTCATCCGGCCCATCGAGGTTGTCAAGGGCGATACGGTGGTGGCCGACTACGGCGAGTTCGGCACCGTTTCTTG
CCACTTCGGATGA

Upstream 100 bases:

>100_bases
AACGTCGTGAAGGCCGAAGAGGTGGCGCCATGAAACGACATCCTGTGTTAGCCCGGTGTTTTTGCTTGCCTGCGGCCTCG
ACCGGCAGGAGGGTAGTCCG

Downstream 100 bases:

>100_bases
ACGACGCGCATGTCCTCCCCCCTCATTTCCGGCGCGCACCCGGGCCGGGGGAATCACTTGGCGCGGTGCGGCCAAGAGCA
CCGGCGCGAGCGCGTTGCGG

Product: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase

Products: NA

Alternate protein names: OHED hydratase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSLDQNTLAQAAERLQQAQRTRLACRQFSLDYPEMTIDDAYAIQHAWMQLELRNGRTIKGHKIGLTSKAMQRAVNIAEPD
YGTLLDDMFYRDGAVIESERFLQLKIEAELAFVLAKPLAGPDCTLFDVLDATAYITPALEILDARIERIDPQTRRMRTVL
DTISDNAANAALVLGGRPFRPAVSDADMRRIGAIVSRNGEVEETGLAAGVLNHPGYGVAWLANRLHRFGVTLQPRQVILA
GSFIRPIEVVKGDTVVADYGEFGTVSCHFG

Sequences:

>Translated_270_residues
MSLDQNTLAQAAERLQQAQRTRLACRQFSLDYPEMTIDDAYAIQHAWMQLELRNGRTIKGHKIGLTSKAMQRAVNIAEPD
YGTLLDDMFYRDGAVIESERFLQLKIEAELAFVLAKPLAGPDCTLFDVLDATAYITPALEILDARIERIDPQTRRMRTVL
DTISDNAANAALVLGGRPFRPAVSDADMRRIGAIVSRNGEVEETGLAAGVLNHPGYGVAWLANRLHRFGVTLQPRQVILA
GSFIRPIEVVKGDTVVADYGEFGTVSCHFG
>Mature_269_residues
SLDQNTLAQAAERLQQAQRTRLACRQFSLDYPEMTIDDAYAIQHAWMQLELRNGRTIKGHKIGLTSKAMQRAVNIAEPDY
GTLLDDMFYRDGAVIESERFLQLKIEAELAFVLAKPLAGPDCTLFDVLDATAYITPALEILDARIERIDPQTRRMRTVLD
TISDNAANAALVLGGRPFRPAVSDADMRRIGAIVSRNGEVEETGLAAGVLNHPGYGVAWLANRLHRFGVTLQPRQVILAG
SFIRPIEVVKGDTVVADYGEFGTVSCHFG

Specific function: Transforms 2-oxo-hept-3-ene-1,7-dioate (OHED) into 2,4- dihydoxy-hept-2-ene-1,7-dioic acid (HHED) [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=230, Percent_Identity=34.7826086956522, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234
- InterPro:   IPR012690 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: 4.2.1.-

Molecular weight: Translated: 29814; Mature: 29683

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDQNTLAQAAERLQQAQRTRLACRQFSLDYPEMTIDDAYAIQHAWMQLELRNGRTIKG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEECCCCEECC
HKIGLTSKAMQRAVNIAEPDYGTLLDDMFYRDGAVIESERFLQLKIEAELAFVLAKPLAG
EEECCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCCEEEEEEEHHEEEEECCCCCC
PDCTLFDVLDATAYITPALEILDARIERIDPQTRRMRTVLDTISDNAANAALVLGGRPFR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
PAVSDADMRRIGAIVSRNGEVEETGLAAGVLNHPGYGVAWLANRLHRFGVTLQPRQVILA
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
GSFIRPIEVVKGDTVVADYGEFGTVSCHFG
CCCCCHHHHCCCCEEEEECCCCCEEEEECC
>Mature Secondary Structure 
SLDQNTLAQAAERLQQAQRTRLACRQFSLDYPEMTIDDAYAIQHAWMQLELRNGRTIKG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEECCCCEECC
HKIGLTSKAMQRAVNIAEPDYGTLLDDMFYRDGAVIESERFLQLKIEAELAFVLAKPLAG
EEECCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCCEEEEEEEHHEEEEECCCCCC
PDCTLFDVLDATAYITPALEILDARIERIDPQTRRMRTVLDTISDNAANAALVLGGRPFR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
PAVSDADMRRIGAIVSRNGEVEETGLAAGVLNHPGYGVAWLANRLHRFGVTLQPRQVILA
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
GSFIRPIEVVKGDTVVADYGEFGTVSCHFG
CCCCCHHHHCCCCEEEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]