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The map label for this gene is proA [H]

Identifier: 121609347

GI number: 121609347

Start: 2703693

End: 2704358

Strand: Direct

Name: proA [H]

Synonym: Veis_2390

Alternate gene names: 121609347

Gene position: 2703693-2704358 (Clockwise)

Preceding gene: 121609346

Following gene: 121609350

Centisome position: 48.57

GC content: 67.27

Gene sequence:

>666_bases
ATGGGTATGAGCACCACCACCGATTCGTTGCTGCCCCGGCTACAGTCCTGCTACACCGGCATCCTGCATGACGTGATGCG
TGCTGCGGGCCTGCGCGACTTCACGCTGCCGCCGACGCTGCGCCCGCTGATCGCCGGGCGCAAACTCTGCGGCCCGGCCT
TCACGGTCAACGGCCGCGTCGATCCCGGCGCCGATCCCCATGAGACGCTGATGGCCTGGACCGGTTTTCTCTCGCGTGCC
GAGCCGGGCCACATCGCCGTGATACAGCCCAACGACTCGGTGGTCGCGCACATGGGCGAGCTTTCGGCCGAAACGCTCGG
CGGCAAGGGCGTGTTGGGCGTGATTGCCGACGGTGGCCTGCGCGATGCCGAGTTCATCATCGCGCAGGGCTTTCAGGTCT
GGCACCGCTACTTCACGCCGCGTGACGTGGTGGGCTACTGGTTGCCGGACGCGCTGCAAGTGCCGGTGCGCATCGGCGCG
GTCACGGTCAACCCGGGCGACCTGCTGCTGGCCGACACCGATGGCGTGATCTGCATTCCACTGGCGCAGGCCGAGGCGGT
GATCAGCCAGGCCGAGACCATGATGGCGCGCGAAAACCTCGTGCGCAGCGCCATCCTCACCGGCACCGACCCGCAACAGG
CCTACCTGAAGTACCGCAAGTTCTGA

Upstream 100 bases:

>100_bases
GTTGCTCGACCACCTGGCGCAGCCGGGTTAGTGCGCCGGGTTTTTCCAAAATCGGTTTCCTCCGGGCAAACCAGAAACTT
CCAGAGACCGCAACAGAGAC

Downstream 100 bases:

>100_bases
AGACCGCCAACAACGGTGCGCCCCGTGCAATCCCTGATCCCACCGGCTGGCGAATGACGATGTGGTTTGCATGAATTTCG
TTCATTCGCTCATTCGTTCG

Product: putative methyltransferase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MGMSTTTDSLLPRLQSCYTGILHDVMRAAGLRDFTLPPTLRPLIAGRKLCGPAFTVNGRVDPGADPHETLMAWTGFLSRA
EPGHIAVIQPNDSVVAHMGELSAETLGGKGVLGVIADGGLRDAEFIIAQGFQVWHRYFTPRDVVGYWLPDALQVPVRIGA
VTVNPGDLLLADTDGVICIPLAQAEAVISQAETMMARENLVRSAILTGTDPQQAYLKYRKF

Sequences:

>Translated_221_residues
MGMSTTTDSLLPRLQSCYTGILHDVMRAAGLRDFTLPPTLRPLIAGRKLCGPAFTVNGRVDPGADPHETLMAWTGFLSRA
EPGHIAVIQPNDSVVAHMGELSAETLGGKGVLGVIADGGLRDAEFIIAQGFQVWHRYFTPRDVVGYWLPDALQVPVRIGA
VTVNPGDLLLADTDGVICIPLAQAEAVISQAETMMARENLVRSAILTGTDPQQAYLKYRKF
>Mature_220_residues
GMSTTTDSLLPRLQSCYTGILHDVMRAAGLRDFTLPPTLRPLIAGRKLCGPAFTVNGRVDPGADPHETLMAWTGFLSRAE
PGHIAVIQPNDSVVAHMGELSAETLGGKGVLGVIADGGLRDAEFIIAQGFQVWHRYFTPRDVVGYWLPDALQVPVRIGAV
TVNPGDLLLADTDGVICIPLAQAEAVISQAETMMARENLVRSAILTGTDPQQAYLKYRKF

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 23809; Mature: 23678

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMSTTTDSLLPRLQSCYTGILHDVMRAAGLRDFTLPPTLRPLIAGRKLCGPAFTVNGRV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHCCCEEEECCCC
DPGADPHETLMAWTGFLSRAEPGHIAVIQPNDSVVAHMGELSAETLGGKGVLGVIADGGL
CCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCC
RDAEFIIAQGFQVWHRYFTPRDVVGYWLPDALQVPVRIGAVTVNPGDLLLADTDGVICIP
CCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHCCCEEEEEEEECCCCEEEECCCCEEEEE
LAQAEAVISQAETMMARENLVRSAILTGTDPQQAYLKYRKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
GMSTTTDSLLPRLQSCYTGILHDVMRAAGLRDFTLPPTLRPLIAGRKLCGPAFTVNGRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHCCCEEEECCCC
DPGADPHETLMAWTGFLSRAEPGHIAVIQPNDSVVAHMGELSAETLGGKGVLGVIADGGL
CCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCC
RDAEFIIAQGFQVWHRYFTPRDVVGYWLPDALQVPVRIGAVTVNPGDLLLADTDGVICIP
CCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHCCCEEEEEEEECCCCEEEECCCCEEEEE
LAQAEAVISQAETMMARENLVRSAILTGTDPQQAYLKYRKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]