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The map label for this gene is aroE [H]

Identifier: 229576791

GI number: 229576791

Start: 2835658

End: 2836485

Strand: Reverse

Name: aroE [H]

Synonym: BCG_2575c

Alternate gene names: 229576791

Gene position: 2836485-2835658 (Counterclockwise)

Preceding gene: 121638438

Following gene: 121638436

Centisome position: 64.84

GC content: 71.14

Gene sequence:

>828_bases
GTGTCCTCGACAGCGCGCGATGAGCGAAGGTCCCAAAAAGCCGGCGTGCTTGGTTCGCCGATCGCGCATTCCCGCTCCCC
GCAGCTGCACCTGGCCGCCTACCGGGCGTTGGGGCTGCACGACTGGACCTATGAGCGCATCGAATGCGGTGCGGCCGAGT
TGCCCGTCGTGGTCGGTGGTTTCGGACCGGAGTGGGTCGGTGTTTCGGTGACCATGCCGGGCAAGTTCGCCGCCCTGCGG
TTCGCCGACGAGCGCACCGCACGCGCGGACCTTGTCGGTTCGGCCAACACCCTGGTTCGGACGCCGCATGGCTGGCGGGC
CGACAACACCGACATCGACGGGGTGGCCGGGGCGTTGGGGGCGGCTGCTGGACACGCGCTGGTGCTGGGGTCCGGGGGGA
CCGCACCGGCGGCCGTGGTGGGGCTGGCCGAACTCGGGGTCACCGACATCACCGTGGTGGCGCGCAACTCGGACAAGGCG
GCCCGGCTGGTGGACCTGGGCACACGGGTCGGCGTGGCGACCCGGTTCTGCGCGTTCGACAGCGGTGGGTTGGCCGATGC
GGTGGCCGCCGCGGAAGTGCTGGTCAGCACCATTCCAGCGGAGGTGGCCGCGGGGTATGCCGGCACCTTGGCCGCGATCC
CGGTGCTGTTGGACGCCATCTACGATCCGTGGCCCACACCGCTGGCCGCCGCGGTCGGATCGGCGGGCGGGCGGGTGATC
AGCGGGCTGCAGATGTTGCTGCATCAGGCGTTCGCGCAGGTGGAGCAGTTCACCGGGCTACCCGCCCCCCGCGAAGCGAT
GACTTGCGCGCTGGCCGCGTTGGACTAG

Upstream 100 bases:

>100_bases
GACTGGCTGTACTTCGTCACCATCGATTCCCAGGGCACGACGCTGTTCACCAGGGACTATCAGCAGCATCTGGCGAACAT
CGAGCTGGCCAAACACAACG

Downstream 100 bases:

>100_bases
CGTGCCCCAGCATGCTGGCGGCGGCGGTGTTGGCCTGGATGGGAGTGTTGTGCGTTTGCGACGTCCGGCAGCGCCGGCTA
CCCAACTGGCTCACCCTGCC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSSTARDERRSQKAGVLGSPIAHSRSPQLHLAAYRALGLHDWTYERIECGAAELPVVVGGFGPEWVGVSVTMPGKFAALR
FADERTARADLVGSANTLVRTPHGWRADNTDIDGVAGALGAAAGHALVLGSGGTAPAAVVGLAELGVTDITVVARNSDKA
ARLVDLGTRVGVATRFCAFDSGGLADAVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGGRVI
SGLQMLLHQAFAQVEQFTGLPAPREAMTCALAALD

Sequences:

>Translated_275_residues
MSSTARDERRSQKAGVLGSPIAHSRSPQLHLAAYRALGLHDWTYERIECGAAELPVVVGGFGPEWVGVSVTMPGKFAALR
FADERTARADLVGSANTLVRTPHGWRADNTDIDGVAGALGAAAGHALVLGSGGTAPAAVVGLAELGVTDITVVARNSDKA
ARLVDLGTRVGVATRFCAFDSGGLADAVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGGRVI
SGLQMLLHQAFAQVEQFTGLPAPREAMTCALAALD
>Mature_274_residues
SSTARDERRSQKAGVLGSPIAHSRSPQLHLAAYRALGLHDWTYERIECGAAELPVVVGGFGPEWVGVSVTMPGKFAALRF
ADERTARADLVGSANTLVRTPHGWRADNTDIDGVAGALGAAAGHALVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAA
RLVDLGTRVGVATRFCAFDSGGLADAVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGGRVIS
GLQMLLHQAFAQVEQFTGLPAPREAMTCALAALD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=275, Percent_Identity=29.4545454545455, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789675, Length=251, Percent_Identity=29.0836653386454, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320332, Length=288, Percent_Identity=31.5972222222222, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 27984; Mature: 27853

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTARDERRSQKAGVLGSPIAHSRSPQLHLAAYRALGLHDWTYERIECGAAELPVVVGG
CCCCCHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHCCCCCCHHHHHCCCCCCCEEEEC
FGPEWVGVSVTMPGKFAALRFADERTARADLVGSANTLVRTPHGWRADNTDIDGVAGALG
CCCCCEEEEEECCCCEEEEEECCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHH
AAAGHALVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATRFCAFD
HCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHCHHHHHHHHHHCCC
SGGLADAVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGGRVI
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHH
SGLQMLLHQAFAQVEQFTGLPAPREAMTCALAALD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SSTARDERRSQKAGVLGSPIAHSRSPQLHLAAYRALGLHDWTYERIECGAAELPVVVGG
CCCCHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHCCCCCCHHHHHCCCCCCCEEEEC
FGPEWVGVSVTMPGKFAALRFADERTARADLVGSANTLVRTPHGWRADNTDIDGVAGALG
CCCCCEEEEEECCCCEEEEEECCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHH
AAAGHALVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATRFCAFD
HCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHCHHHHHHHHHHCCC
SGGLADAVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGGRVI
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHH
SGLQMLLHQAFAQVEQFTGLPAPREAMTCALAALD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA