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The map label for this gene is dnaQ [H]

Identifier: 121639627

GI number: 121639627

Start: 4129426

End: 4130415

Strand: Reverse

Name: dnaQ [H]

Synonym: BCG_3771c

Alternate gene names: 121639627

Gene position: 4130415-4129426 (Counterclockwise)

Preceding gene: 121639630

Following gene: 121639625

Centisome position: 94.42

GC content: 67.47

Gene sequence:

>990_bases
GTGAGCCACACCTGGGGACGGCCAGCCAGCCACCAGGATCGGGGTTGGGCCGTCATCGACGTCGAGACCTCGGGCTTTCG
GCCGGGCCAGGCCCGGATCATCAGCCTTGCGGTGCTCGGCCTGGACGCCGCCGGCCGACTAGAGCAATCCGTGGTCAGCC
TGCTAAATCCCAAGGTGGACCCGGGCCCCACCCACGTGCACGGCCTGACCGCCGCCATGCTCGATGACCAGCCACAGTTC
GCCGATATCGCCGGTGAGGTTGTCGACGTGCTGCGCGGGCGCACTCTGGTCGCGCACAATGTCGCGTTCGACTATGCGTT
TCTCGCTGCGGAGGCCGAGATCGCCGAGGCCGAACTCCCGGTTGACTTCGTCATGTGCACGGTCGAGCTGGCCCGCCGGC
TGCAGCTTGGCGTCGACAATCTGCGGCTGGAGACACTTGCCGCGCATTGGGGTGTGCCCCAGCAACGGCCGCACGATGCA
TTCGACGACGCCCGGGTATTGACCGGGATACTGGCAGCTGCCCTAGAGAGTGCGCGCGAACTCGACGTCTGGCTGCCGGT
GCACCCGGTGACACGGCGCCGGTGGCCCAACGGCCGGGTGACTCACGACGAGCTGCGACCGCTGAAGGCCTTGGCAGCCC
GGATGGCCTGCCCCTACCTCAACCCGGGCCGGTATGTCCAGGGCCGCCCGCTGGTCCAGGGCATGCGGGTGGGGCTGGCG
GCCGAGGTAAAACGGACCCACGAGGAACTCGTCGAACGGATTCTGCACGCCGGGCTGGCCTACAGCGACGTCGTAGACCG
GGATACCTCACTGGTGGTCTGCAACGCGACCGCCCCCGAACACGGCAAGGGCTATCACGCCCTGCAGCTGGGGGTTCCGG
TGATGCCTGAAGCGCGATTCATGGAGTGCATCGGTGCCGTCGTCGGGGGCGCCAGCGTGGAGGACTTCACCGACGTCGCT
CCCGTCGAAAAGCAGTTAGCGTTGTTCTGA

Upstream 100 bases:

>100_bases
CTTGTCGCCGGGTGCGGCGGGTCGCCCGCGTCCGGGTTTTACGGGCCGACACGATGCGTAGCGACCAGGTGATGTCGCTC
GGACGTGTCATCCTCGTCTT

Downstream 100 bases:

>100_bases
AACGGCGAGCGGAACGTCACTGCGAAAAATCATGCCGCGGACCCCGACCCTAGTTCAGCGCCGTCCTAGCGTGCCGCCCG
GTTGACCGCCGACACCACGG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSHTWGRPASHQDRGWAVIDVETSGFRPGQARIISLAVLGLDAAGRLEQSVVSLLNPKVDPGPTHVHGLTAAMLDDQPQF
ADIAGEVVDVLRGRTLVAHNVAFDYAFLAAEAEIAEAELPVDFVMCTVELARRLQLGVDNLRLETLAAHWGVPQQRPHDA
FDDARVLTGILAAALESARELDVWLPVHPVTRRRWPNGRVTHDELRPLKALAARMACPYLNPGRYVQGRPLVQGMRVGLA
AEVKRTHEELVERILHAGLAYSDVVDRDTSLVVCNATAPEHGKGYHALQLGVPVMPEARFMECIGAVVGGASVEDFTDVA
PVEKQLALF

Sequences:

>Translated_329_residues
MSHTWGRPASHQDRGWAVIDVETSGFRPGQARIISLAVLGLDAAGRLEQSVVSLLNPKVDPGPTHVHGLTAAMLDDQPQF
ADIAGEVVDVLRGRTLVAHNVAFDYAFLAAEAEIAEAELPVDFVMCTVELARRLQLGVDNLRLETLAAHWGVPQQRPHDA
FDDARVLTGILAAALESARELDVWLPVHPVTRRRWPNGRVTHDELRPLKALAARMACPYLNPGRYVQGRPLVQGMRVGLA
AEVKRTHEELVERILHAGLAYSDVVDRDTSLVVCNATAPEHGKGYHALQLGVPVMPEARFMECIGAVVGGASVEDFTDVA
PVEKQLALF
>Mature_328_residues
SHTWGRPASHQDRGWAVIDVETSGFRPGQARIISLAVLGLDAAGRLEQSVVSLLNPKVDPGPTHVHGLTAAMLDDQPQFA
DIAGEVVDVLRGRTLVAHNVAFDYAFLAAEAEIAEAELPVDFVMCTVELARRLQLGVDNLRLETLAAHWGVPQQRPHDAF
DDARVLTGILAAALESARELDVWLPVHPVTRRRWPNGRVTHDELRPLKALAARMACPYLNPGRYVQGRPLVQGMRVGLAA
EVKRTHEELVERILHAGLAYSDVVDRDTSLVVCNATAPEHGKGYHALQLGVPVMPEARFMECIGAVVGGASVEDFTDVAP
VEKQLALF

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=169, Percent_Identity=29.585798816568, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR006054
- InterPro:   IPR006310
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650
- InterPro:   IPR006935
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 35826; Mature: 35695

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTWGRPASHQDRGWAVIDVETSGFRPGQARIISLAVLGLDAAGRLEQSVVSLLNPKVD
CCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHEEEEEEECCCCHHHHHHHHHHHHCCCCC
PGPTHVHGLTAAMLDDQPQFADIAGEVVDVLRGRTLVAHNVAFDYAFLAAEAEIAEAELP
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCC
VDFVMCTVELARRLQLGVDNLRLETLAAHWGVPQQRPHDAFDDARVLTGILAAALESARE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LDVWLPVHPVTRRRWPNGRVTHDELRPLKALAARMACPYLNPGRYVQGRPLVQGMRVGLA
CEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
AEVKRTHEELVERILHAGLAYSDVVDRDTSLVVCNATAPEHGKGYHALQLGVPVMPEARF
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCHHHH
MECIGAVVGGASVEDFTDVAPVEKQLALF
HHHHHHHHCCCCHHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
SHTWGRPASHQDRGWAVIDVETSGFRPGQARIISLAVLGLDAAGRLEQSVVSLLNPKVD
CCCCCCCCCCCCCCEEEEEEECCCCCCCHHHEEEEEEECCCCHHHHHHHHHHHHCCCCC
PGPTHVHGLTAAMLDDQPQFADIAGEVVDVLRGRTLVAHNVAFDYAFLAAEAEIAEAELP
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCC
VDFVMCTVELARRLQLGVDNLRLETLAAHWGVPQQRPHDAFDDARVLTGILAAALESARE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LDVWLPVHPVTRRRWPNGRVTHDELRPLKALAARMACPYLNPGRYVQGRPLVQGMRVGLA
CEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
AEVKRTHEELVERILHAGLAYSDVVDRDTSLVVCNATAPEHGKGYHALQLGVPVMPEARF
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCHHHH
MECIGAVVGGASVEDFTDVAPVEKQLALF
HHHHHHHHCCCCHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]