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The map label for this gene is virS [H]

Identifier: 121638967

GI number: 121638967

Start: 3401890

End: 3402912

Strand: Reverse

Name: virS [H]

Synonym: BCG_3107c

Alternate gene names: 121638967

Gene position: 3402912-3401890 (Counterclockwise)

Preceding gene: 121638977

Following gene: 121638965

Centisome position: 77.79

GC content: 66.76

Gene sequence:

>1023_bases
ATGGAGCTGGGCAGCCTCATCCGCGCCACCAACCTGTGGGGGTACACCGACCTGATGCGCGAGCTCGGCGCGGACCCGCT
GCCGTTTCTGCGGCGCTTCGACATCCCGCCGGGCATCGAACACCAAGAGGACGCGTTCATGTCGCTGGCCGGGTTCGTGC
GCATGCTGGAGGCCAGCGCCGCCGAGCTCGATTGCCCGGACTTCGGACTACGCCTTGCACGCTGGCAGGGCCTGGGCATT
CTCGGCCCGGTAGCGGTGATCGCGCGCAACGCTGCCACCTTGTTCGGCGGGCTGGAGGCGATCGGTCGCTACCTCTACGT
CCATTCGCCCGCCCTGACGCTGACGGTTTCATCAACTACCGCACGGTCCAACGTCCGGTTCGGCTATGAGGTGACCGAAC
CGGGGATTCCCTATCCGCTGCAGGGATACGAGCTGAGCATGGCCAACGCCGCCCGGATGATCCGCCTGCTGGGCGGACCG
CAGGCGCGGGCGCGCGTTTTCTCGTTCCGACATGCGCAACTGGGCACCGACGCCGCCTACCGCGAAGCGTTGGGTTGTAC
CGTTCGGTTCGGCCGGACATGGTGCGGGTTCGAGGTGGACCACCGGCTCGCCGGTAGGCCCATCGACCATGCGGATCCGG
AAACCAAGCGCATCGCCACGAAATATTTGGAATCCCAATACCTTCCGAGCGATGCCACGCTCTCCGAGCGGGTCGTCGGG
TTGGCCCGCCGCCTGCTGCCGACCGGCCAATGCAGCGCCGAGGCCATCGCCGACCAACTCGACATGCACCCACGAACGCT
GCAGCGGCGCTTGGCTGCCGAGGGCCTCCGGTGCCATGACCTCATCGAGCGCGAACGCCGTGCGCAAGCGGCAAGGTACC
TCGCCCAACCGGGGTTGTATCTGAGCCAAATCGCGGTGCTGCTCGGCTATTCCGAGCAGAGCGCGCTCAACCGGTCGTGC
CGGTGCTGGTTTGGGATGACACCCCGGCAGTATCGAGCCTATGGTGGGGTCAGCGGTCGGTGA

Upstream 100 bases:

>100_bases
AGGACGTCGAAATGCTGGTTCATGGCTCCAGCATGGTGGAGGACCCCCGCCACGTATTGACACTTTGCGACAGCCTTTTA
TCATTTTCCGACAGGAGGTG

Downstream 100 bases:

>100_bases
AACGGGTGGTGAAACCCCAGCCCCGACTGACAGAAGCGGTTCGCATTGGGGACGCCCGAATCATGGATAATCCATGACAC
TGGGGTGCTGCGCGCGGCGG

Product: virulence-regulating transcriptional regulator VirS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MELGSLIRATNLWGYTDLMRELGADPLPFLRRFDIPPGIEHQEDAFMSLAGFVRMLEASAAELDCPDFGLRLARWQGLGI
LGPVAVIARNAATLFGGLEAIGRYLYVHSPALTLTVSSTTARSNVRFGYEVTEPGIPYPLQGYELSMANAARMIRLLGGP
QARARVFSFRHAQLGTDAAYREALGCTVRFGRTWCGFEVDHRLAGRPIDHADPETKRIATKYLESQYLPSDATLSERVVG
LARRLLPTGQCSAEAIADQLDMHPRTLQRRLAAEGLRCHDLIERERRAQAARYLAQPGLYLSQIAVLLGYSEQSALNRSC
RCWFGMTPRQYRAYGGVSGR

Sequences:

>Translated_340_residues
MELGSLIRATNLWGYTDLMRELGADPLPFLRRFDIPPGIEHQEDAFMSLAGFVRMLEASAAELDCPDFGLRLARWQGLGI
LGPVAVIARNAATLFGGLEAIGRYLYVHSPALTLTVSSTTARSNVRFGYEVTEPGIPYPLQGYELSMANAARMIRLLGGP
QARARVFSFRHAQLGTDAAYREALGCTVRFGRTWCGFEVDHRLAGRPIDHADPETKRIATKYLESQYLPSDATLSERVVG
LARRLLPTGQCSAEAIADQLDMHPRTLQRRLAAEGLRCHDLIERERRAQAARYLAQPGLYLSQIAVLLGYSEQSALNRSC
RCWFGMTPRQYRAYGGVSGR
>Mature_340_residues
MELGSLIRATNLWGYTDLMRELGADPLPFLRRFDIPPGIEHQEDAFMSLAGFVRMLEASAAELDCPDFGLRLARWQGLGI
LGPVAVIARNAATLFGGLEAIGRYLYVHSPALTLTVSSTTARSNVRFGYEVTEPGIPYPLQGYELSMANAARMIRLLGGP
QARARVFSFRHAQLGTDAAYREALGCTVRFGRTWCGFEVDHRLAGRPIDHADPETKRIATKYLESQYLPSDATLSERVVG
LARRLLPTGQCSAEAIADQLDMHPRTLQRRLAAEGLRCHDLIERERRAQAARYLAQPGLYLSQIAVLLGYSEQSALNRSC
RCWFGMTPRQYRAYGGVSGR

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37737; Mature: 37737

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELGSLIRATNLWGYTDLMRELGADPLPFLRRFDIPPGIEHQEDAFMSLAGFVRMLEASA
CCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AELDCPDFGLRLARWQGLGILGPVAVIARNAATLFGGLEAIGRYLYVHSPALTLTVSSTT
HCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEEECCC
ARSNVRFGYEVTEPGIPYPLQGYELSMANAARMIRLLGGPQARARVFSFRHAQLGTDAAY
CCCCCEECEEECCCCCCCCCCCCEECHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHH
REALGCTVRFGRTWCGFEVDHRLAGRPIDHADPETKRIATKYLESQYLPSDATLSERVVG
HHHHCCEEEECCEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
LARRLLPTGQCSAEAIADQLDMHPRTLQRRLAAEGLRCHDLIERERRAQAARYLAQPGLY
HHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHH
LSQIAVLLGYSEQSALNRSCRCWFGMTPRQYRAYGGVSGR
HHHHHHHHCCCHHHHHCCCCEEEECCCHHHHHHCCCCCCC
>Mature Secondary Structure
MELGSLIRATNLWGYTDLMRELGADPLPFLRRFDIPPGIEHQEDAFMSLAGFVRMLEASA
CCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AELDCPDFGLRLARWQGLGILGPVAVIARNAATLFGGLEAIGRYLYVHSPALTLTVSSTT
HCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEEECCC
ARSNVRFGYEVTEPGIPYPLQGYELSMANAARMIRLLGGPQARARVFSFRHAQLGTDAAY
CCCCCEECEEECCCCCCCCCCCCEECHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHH
REALGCTVRFGRTWCGFEVDHRLAGRPIDHADPETKRIATKYLESQYLPSDATLSERVVG
HHHHCCEEEECCEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
LARRLLPTGQCSAEAIADQLDMHPRTLQRRLAAEGLRCHDLIERERRAQAARYLAQPGLY
HHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHH
LSQIAVLLGYSEQSALNRSCRCWFGMTPRQYRAYGGVSGR
HHHHHHHHCCCHHHHHCCCCEEEECCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]