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The map label for this gene is fixB [H]

Identifier: 121638911

GI number: 121638911

Start: 3341507

End: 3342463

Strand: Reverse

Name: fixB [H]

Synonym: BCG_3051c

Alternate gene names: 121638911

Gene position: 3342463-3341507 (Counterclockwise)

Preceding gene: 121638912

Following gene: 121638910

Centisome position: 76.41

GC content: 69.28

Gene sequence:

>957_bases
ATGGCTGAAGTACTGGTGCTCGTTGAGCACGCTGAAGGCGCGTTAAAGAAGGTCAGCGCCGAATTGATCACCGCCGCCCG
CGCCTTGGGCGAACCAGCCGCCGTCGTCGTCGGTGTGCCGGGGACGGCCGCGCCGCTGGTGGACGGGCTTAAGGCGGCTG
GTGCCGCCAAGATCTACGTCGCCGAGTCCGACCTTGTCGACAAATACCTGATCACCCCGGCGGTCGACGTGCTGGCCGGG
CTGGCCGAGTCCTCGGCCCCTGCCGGCGTACTAATCGCCGCCACCGCGGACGGCAAGGAGATCGCCGGCCGACTTGCGGC
TCGGATCGGCTCGGGTCTGCTGGTCGACGTGGTCGACGTGAGAGAAGGTGGAGTGGGTGTCCACAGCATCTTCGGTGGGG
CGTTCACCGTCGAAGCGCAGGCCAACGGCGACACCCCGGTGATCACCGTGCGCGCAGGAGCCGTGGAGGCGGAGCCGGCC
GCCGGCGCCGGTGAGCAGGTCAGCGTGGAAGTGCCGGCTGCGGCGGAGAACGCCGCCAGGATCACCGCGCGCGAACCGGC
GGTCGCCGGCGACCGGCCGGAGCTGACCGAGGCGACCATTGTGGTGGCCGGTGGCCGTGGTGTCGGCAGCGCGGAGAACT
TCAGCGTGGTCGAGGCGCTGGCCGACTCGCTGGGCGCCGCGGTCGGGGCCTCGCGTGCCGCAGTCGACTCCGGCTACTAC
CCGGGCCAGTTCCAGGTCGGCCAGACCGGCAAGACGGTGTCGCCCCAGCTCTACATTGCCCTGGGCATCTCCGGGGCGAT
CCAGCACCGCGCTGGCATGCAGACGTCCAAGACCATCGTCGCGGTCAACAAGGACGAAGAGGCGCCGATCTTTGAGATCG
CCGACTACGGGGTGGTGGGAGACCTGTTCAAGGTCGCTCCGCAGCTGACCGAGGTCATCAAGGCCCGCAAGGGCTAG

Upstream 100 bases:

>100_bases
CCGACGAGGGTGAAGGCGGCAACCAGATCGTGCAGTACCTGGTTGCCCAGAAAATCATCTAAGACATACGCACCTCCCAA
AGACGAGAGCGATATAACCC

Downstream 100 bases:

>100_bases
GTTCCCTGCGCGAGCAGTCGCAAAAGACCCCGACACGCCGAGGCGTGGGGGGCCTTGGCGCCTGCTCACCTAGCCCAACA
GTTCGTCATCTGACGTGCAC

Product: putative electron transfer flavoprotein (alpha-subunit) fixB

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAEVLVLVEHAEGALKKVSAELITAARALGEPAAVVVGVPGTAAPLVDGLKAAGAAKIYVAESDLVDKYLITPAVDVLAG
LAESSAPAGVLIAATADGKEIAGRLAARIGSGLLVDVVDVREGGVGVHSIFGGAFTVEAQANGDTPVITVRAGAVEAEPA
AGAGEQVSVEVPAAAENAARITAREPAVAGDRPELTEATIVVAGGRGVGSAENFSVVEALADSLGAAVGASRAAVDSGYY
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVGDLFKVAPQLTEVIKARKG

Sequences:

>Translated_318_residues
MAEVLVLVEHAEGALKKVSAELITAARALGEPAAVVVGVPGTAAPLVDGLKAAGAAKIYVAESDLVDKYLITPAVDVLAG
LAESSAPAGVLIAATADGKEIAGRLAARIGSGLLVDVVDVREGGVGVHSIFGGAFTVEAQANGDTPVITVRAGAVEAEPA
AGAGEQVSVEVPAAAENAARITAREPAVAGDRPELTEATIVVAGGRGVGSAENFSVVEALADSLGAAVGASRAAVDSGYY
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVGDLFKVAPQLTEVIKARKG
>Mature_317_residues
AEVLVLVEHAEGALKKVSAELITAARALGEPAAVVVGVPGTAAPLVDGLKAAGAAKIYVAESDLVDKYLITPAVDVLAGL
AESSAPAGVLIAATADGKEIAGRLAARIGSGLLVDVVDVREGGVGVHSIFGGAFTVEAQANGDTPVITVRAGAVEAEPAA
GAGEQVSVEVPAAAENAARITAREPAVAGDRPELTEATIVVAGGRGVGSAENFSVVEALADSLGAAVGASRAAVDSGYYP
GQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVGDLFKVAPQLTEVIKARKG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=316, Percent_Identity=42.4050632911392, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI189181759, Length=271, Percent_Identity=43.5424354243542, Blast_Score=209, Evalue=2e-54,
Organism=Escherichia coli, GI1787990, Length=236, Percent_Identity=34.7457627118644, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1786226, Length=229, Percent_Identity=37.5545851528384, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI87082157, Length=244, Percent_Identity=32.3770491803279, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=313, Percent_Identity=36.741214057508, Blast_Score=187, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6325261, Length=321, Percent_Identity=34.8909657320872, Blast_Score=169, Evalue=5e-43,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=42.1725239616613, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=42.1725239616613, Blast_Score=209, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31719; Mature: 31588

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLVLVEHAEGALKKVSAELITAARALGEPAAVVVGVPGTAAPLVDGLKAAGAAKIYV
CCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEE
AESDLVDKYLITPAVDVLAGLAESSAPAGVLIAATADGKEIAGRLAARIGSGLLVDVVDV
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEEE
REGGVGVHSIFGGAFTVEAQANGDTPVITVRAGAVEAEPAAGAGEQVSVEVPAAAENAAR
CCCCCCHHHCCCCEEEEEEECCCCCCEEEEEECCEECCCCCCCCCEEEEECCCCCCCCEE
ITAREPAVAGDRPELTEATIVVAGGRGVGSAENFSVVEALADSLGAAVGASRAAVDSGYY
EEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCC
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVG
CCEEEECCCCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCHHH
DLFKVAPQLTEVIKARKG
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEVLVLVEHAEGALKKVSAELITAARALGEPAAVVVGVPGTAAPLVDGLKAAGAAKIYV
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEE
AESDLVDKYLITPAVDVLAGLAESSAPAGVLIAATADGKEIAGRLAARIGSGLLVDVVDV
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEEE
REGGVGVHSIFGGAFTVEAQANGDTPVITVRAGAVEAEPAAGAGEQVSVEVPAAAENAAR
CCCCCCHHHCCCCEEEEEEECCCCCCEEEEEECCEECCCCCCCCCEEEEECCCCCCCCEE
ITAREPAVAGDRPELTEATIVVAGGRGVGSAENFSVVEALADSLGAAVGASRAAVDSGYY
EEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCC
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVG
CCEEEECCCCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCHHH
DLFKVAPQLTEVIKARKG
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]