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The map label for this gene is hupB [H]

Identifier: 121638867

GI number: 121638867

Start: 3297690

End: 3298307

Strand: Reverse

Name: hupB [H]

Synonym: BCG_3007c

Alternate gene names: 121638867

Gene position: 3298307-3297690 (Counterclockwise)

Preceding gene: 121638868

Following gene: 121638863

Centisome position: 75.4

GC content: 64.08

Gene sequence:

>618_bases
ATGAACAAAGCAGAGCTCATTGACGTGCTCACACAGAAATTGGGCTCGGACCGTCGGCAGGCGACCGCCGCCGTCGAGAA
TGTCGTTGACACGATTGTGCGTGCGGTACACAAAGGCGACAGCGTCACCATTACCGGGTTCGGTGTGTTCGAACAGCGTC
GCCGCGCGGCTCGAGTGGCCCGCAATCCGCGTACCGGCGAGACAGTAAAGGTGAAGCCGACGTCGGTGCCGGCGTTCCGC
CCGGGCGCGCAATTCAAAGCGGTTGTGTCTGGCGCGCAGCGTCTCCCGGCAGAAGGACCCGCTGTTAAGCGTGGTGTGGG
GGCCAGTGCAGCCAAGAAGGTAGCGAAGAAGGCACCTGCCAAGAAGGCGACAAAGGCCGCCAAGAAGGCGGCGACCAAGG
CGCCCGCCAAGAAAGCGGCGACCAAGGCGCCCGCCAAGAAAGCTGTCAAGGCCACGAAGTCACCCGCCAAGAAGGTGACC
AAGGCGGTGAAGAAGACCGCGGTCAAGGCATCGGTGCGTAAGGCGGCGACCAAGGCGCCGGCAAAGAAGGCAGCGGCCAA
GCGGCCGGCTACCAAGGCTCCCGCCAAGAAGGCAACCGCTCGGCGGGGTCGCAAATAG

Upstream 100 bases:

>100_bases
TCAGTGAAATTGCGCGTGGCTCTTGGAAATCAGCCGGGTAAGGGTTTACCGTGTCCACTAGTCGGTTCCAAACGAGGACC
ACTGGTTTCGGAGGGTTGGG

Downstream 100 bases:

>100_bases
GTCAAGACACACGGATACCCTTTGCACGGTGGCAATGTGACGAAGGGTATCCGTGTGTTAGGCCCGCACGTTGGCGGCCA
GCGCACCGCCGATGTGGTCG

Product: putative DNA-binding protein HU homolog hupB

Products: NA

Alternate protein names: Histone-like protein; Hlp [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFR
PGAQFKAVVSGAQRLPAEGPAVKRGVGASAAKKVAKKAPAKKATKAAKKAATKAPAKKAATKAPAKKAVKATKSPAKKVT
KAVKKTAVKASVRKAATKAPAKKAAAKRPATKAPAKKATARRGRK

Sequences:

>Translated_205_residues
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFR
PGAQFKAVVSGAQRLPAEGPAVKRGVGASAAKKVAKKAPAKKATKAAKKAATKAPAKKAATKAPAKKAVKATKSPAKKVT
KAVKKTAVKASVRKAATKAPAKKAAAKRPATKAPAKKATARRGRK
>Mature_205_residues
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFR
PGAQFKAVVSGAQRLPAEGPAVKRGVGASAAKKVAKKAPAKKATKAAKKAATKAPAKKAATKAPAKKAVKATKSPAKKVT
KAVKKTAVKASVRKAATKAPAKKAAAKRPATKAPAKKATARRGRK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=41.5730337078652, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=39.1304347826087, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786644, Length=92, Percent_Identity=36.9565217391304, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 21292; Mature: 21292

Theoretical pI: Translated: 12.44; Mature: 12.44

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVA
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHH
RNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPAEGPAVKRGVGASAAKKVAKKAPA
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCH
KKATKAAKKAATKAPAKKAATKAPAKKAVKATKSPAKKVTKAVKKTAVKASVRKAATKAP
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKKAAAKRPATKAPAKKATARRGRK
HHHHHHCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVA
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHH
RNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPAEGPAVKRGVGASAAKKVAKKAPA
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCH
KKATKAAKKAATKAPAKKAATKAPAKKAVKATKSPAKKVTKAVKKTAVKASVRKAATKAP
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKKAAAKRPATKAPAKKATARRGRK
HHHHHHCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]