Click here to switch to the map view.

The map label for this gene is mrdA [C]

Identifier: 121638746

GI number: 121638746

Start: 3129386

End: 3131197

Strand: Reverse

Name: mrdA [C]

Synonym: BCG_2886c

Alternate gene names: 121638746

Gene position: 3131197-3129386 (Counterclockwise)

Preceding gene: 121638749

Following gene: 121638744

Centisome position: 71.58

GC content: 66.72

Gene sequence:

>1812_bases
ATGGTAACTAAAACAACATTAGCCTCAGCCACCTCAGGTTTGCTGCTGCTTGCGGTCGTCGCCATGTCGGGCTGCACCCC
GCGTCCCCAAGGGCCCGGTCCGGCGGCCGAAAAGTTCTTCGCCGCGCTGGCCATCGGTGACACCGCCTCCGCCGCCCAGC
TCAGCGACAACCCCAACGAGGCGCGCGAAGCGCTGAACGCGGCCTGGGCGGGGCTGCAGGCCGCCCACCTGGATGCGCAG
GTTCTCAGCGCCAAGTACGCCGAGGACACCGGTACGGTCGCTTATCGCTTCAGCTGGCATCTGCCCAAGGACCGAATCTG
GACCTATGACGGCCAGCTGAAGATGGCCCGCGACGAAGGGCGTTGGCACGTTCGCTGGACCACCAGCGGGTTGCATCCCA
AGCTAGGCGAACATCAAACGTTCGCGCTACGAGCCGACCCGCCGCGGCGCGCCTCGGTGAACGAAGTCGGCGGCACCGAT
GTGCTGGTGCCGGGCTATCTGTATCACTACTCGCTGGACGCCGGCCAGGCCGGCCGCGAGCTCTTCGGCACGGCACACGC
GGTGGTGGGCGCGCTGCACCCCTTCGACGACACGCTCAATGATCCGCAGCTGCTGGCCGAACAGGCCAGCTCGTCGACCC
AGCCGTTGGACCTGGTCACGTTGCACGCCGACGACAGCAACCGGGTGGCCGCGGCGATCGGGCAGCTGCCTGGCGTGGTG
ATCACACCGCAGGCCGAGCTGCTCCCGACCGACAAGCACTTCGCGCCGGCGGTCCTCAACGATGTCAAGAAGGCCGTCGT
CGATGAACTCGACGGCAAGGCGGGTTGGCGGGTGGTGAGCGTCAACCAAAATGGCGTCGACGTCTCGGTGCTGCACGAGG
TCGCCCCATCACCTGCGTCGTCGGTTTCGATCACGTTGGATCGGGTCGTGCAAAACGCCGCGCAACACGCGGTGAACACC
CGGGGCGGCAAGGCGATGATCGTCGTGATCAAGCCGTCGACCGGCGAGATCCTGGCGATCGCGCAGAACGCCGGGGCCGA
TGCGGACGGTCCGGTCGCGACCACCGGTCTATATCCACCCGGGTCGACATTCAAGATGATCACCGCCGGTGCGGCCGTCG
AGCGTGACCTGGCTACCCCTGAGACGCTGCTGGGTTGCCCCGGGGAGATCGACATCGGGCATCGCACCATTCCCAACTAC
GGTGGCTTTGATCTGGGCGTGGTGCCGATGTCACGCGCGTTTGCCAGTTCCTGCAACACCACCTTCGCCGAGCTGAGCAG
CAGGCTGCCTCCCCGCGGTCTGACTCAGGCGGCCCGGCGGTACGGGATCGGGCTTGACTACCAGGTGGACGGCATCACCA
CGGTGACCGGTTCGGTGCCGCCGACGGTGGACCTGGCCGAACGCACCGAGGACGGTTTCGGCCAGGGCAAGGTGCTGGCC
AGCCCGTTCGGCATGGCCTTGGTGGCGGCGACGGTAGCCGCCGGGAAGACCCCGGTTCCACAGCTGATCGCCGGCCGGCC
GACGGCCGTCGAAGGCGATGCCACACCGATCAGCCAGAAGATGATCGACGCGCTGCGGCCCATGATGCGGTTGGTGGTGA
CCAATGGCACCGCCAAGGAGATCGCTGGCTGTGGCGAGGTGTTCGGTAAGACCGGCGAAGCCGAATTCCCGGGCGGATCG
CATTCCTGGTTCGCCGGGTACCGTGGCGATCTGGCATTTGCGTCGCTGATCGTCGGGGGCGGTAGCTCGGAATACGCGGT
GCGGATGACCAAGGTGATGTTCGAATCGCTGCCGCCGGGGTACCTGGCGTAG

Upstream 100 bases:

>100_bases
TTCGCGGTGGTGTTCCATTCGCGACCTAGTCTCGGCGTAACGGTTCGGTCTCGGTGTGTCGCGGCCGGTGTCTCCGTCAC
AGTTCTTAACATCAGCAACG

Downstream 100 bases:

>100_bases
CGCGGCTCGCCCCTCCTCGTTTGTACGACGACACGCCGTTAGGGCCGTACAACTGCGGACGCTCGCGCCCACACGGACGC
GTCATGATCGGAATGCGCTG

Product: putative penicillin-binding lipoprotein

Products: NA

Alternate protein names: -Like Protein; Bacterial Membrane Protein; NTF2 Domain-Containing Protein Transpeptidase; Peptidoglycan Synthetase; Protein FtsI; Rod Shape-Determining Protein MrdA; Cell Elongation-Specific Peptidoglycan D D-Transpeptidase; Pbp2 Protein; Cell Elongation Specific D D-Transpeptidase; Division-Specific Transpeptidase; PcbR Involved In Clavulanic Acid Synthesis; Transpeptidase Protein FtsI; Stage V Sporulation Protein D

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNEAREALNAAWAGLQAAHLDAQ
VLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEGRWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTD
VLVPGYLYHYSLDAGQAGRELFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPASSVSITLDRVVQNAAQHAVNT
RGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPPGSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNY
GGFDLGVVPMSRAFASSCNTTFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMIDALRPMMRLVVTNGTAKEIAGCGEVFGKTGEAEFPGGS
HSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPGYLA

Sequences:

>Translated_603_residues
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNEAREALNAAWAGLQAAHLDAQ
VLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEGRWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTD
VLVPGYLYHYSLDAGQAGRELFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPASSVSITLDRVVQNAAQHAVNT
RGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPPGSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNY
GGFDLGVVPMSRAFASSCNTTFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMIDALRPMMRLVVTNGTAKEIAGCGEVFGKTGEAEFPGGS
HSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPGYLA
>Mature_603_residues
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNEAREALNAAWAGLQAAHLDAQ
VLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEGRWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTD
VLVPGYLYHYSLDAGQAGRELFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPASSVSITLDRVVQNAAQHAVNT
RGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPPGSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNY
GGFDLGVVPMSRAFASSCNTTFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMIDALRPMMRLVVTNGTAKEIAGCGEVFGKTGEAEFPGGS
HSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPGYLA

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786854, Length=293, Percent_Identity=24.9146757679181, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 63015; Mature: 63015

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEECCCCCCHHCCCCHHH
AREALNAAWAGLQAAHLDAQVLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEG
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCEEEEEECCC
RWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTDVLVPGYLYHYSLDAGQAGRE
EEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCEEEEEECCCCCCCHH
LFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEE
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPAS
ECCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHCCCCCCC
SVSITLDRVVQNAAQHAVNTRGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPP
CEEEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCEEECCCCCC
GSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNYGGFDLGVVPMSRAFASSCNT
CCCEEEEECCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCH
TFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
HHHHHHHCCCCCHHHHHHHHHCCCCEEEECCEEEEECCCCCCCCHHHHCCCCCCCCCEEE
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMIDALRPMMRLVVTNGTAKE
CCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
IAGCGEVFGKTGEAEFPGGSHSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
YLA
CCC
>Mature Secondary Structure
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEECCCCCCHHCCCCHHH
AREALNAAWAGLQAAHLDAQVLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEG
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCEEEEEECCC
RWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTDVLVPGYLYHYSLDAGQAGRE
EEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCEEEEEECCCCCCCHH
LFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEE
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPAS
ECCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHCCCCCCC
SVSITLDRVVQNAAQHAVNTRGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPP
CEEEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCEEECCCCCC
GSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNYGGFDLGVVPMSRAFASSCNT
CCCEEEEECCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCH
TFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
HHHHHHHCCCCCHHHHHHHHHCCCCEEEECCEEEEECCCCCCCCHHHHCCCCCCCCCEEE
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMIDALRPMMRLVVTNGTAKE
CCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
IAGCGEVFGKTGEAEFPGGSHSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
YLA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA