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The map label for this gene is ycbL [C]

Identifier: 121638466

GI number: 121638466

Start: 2870536

End: 2871210

Strand: Reverse

Name: ycbL [C]

Synonym: BCG_2604c

Alternate gene names: 121638466

Gene position: 2871210-2870536 (Counterclockwise)

Preceding gene: 121638468

Following gene: 121638465

Centisome position: 65.63

GC content: 64.74

Gene sequence:

>675_bases
GTGTTGATCACCGGATTTCCTGCGGGGTTGCTGGCGTGTAACTGTTATGTGCTGGCCGAGCGGCCCGGAACCGACGCCGT
CATCGTCGATCCGGGCCAGGGTGCGATGGGCACGCTGCGTCGCATCCTCGACAAGAACCGGCTGACCCCTGCCGCGGTGC
TGCTCACCCACGGACACATCGATCACATCTGGTCCGCGCAGAAGGTCTCAGACACCTTCGGCTGCCCCACCTATGTGCAT
CCCGCCGACCGGTTCATGCTGACCGACCCCATCTACGGCCTGGGCCCGCGGATAGCGCAGCTGGTTGCGGGTGCGTTCTT
TCGTGAGCCTAAACAGGTTGTGGAGCTGGACCGAGACGGCGACAAGATCGACCTCGGCGGCATCTCGGTCAACATCGATC
ACACACCGGGTCACACCCGCGGGTCGGTGGTCTTCCGGGTCCTGCAGGCGACCAACAACGACAAGGACATCGTGTTCACC
GGTGACACCCTGTTCGAGCGTGCGATAGGCCGCACCGACTTGGCCGGCGGCAGCGGCCGCGACCTGTTGCGCTCCATCGT
CGACAAACTCCTGGTGCTCGACGACAGCACGGTGGTGCTGCCCGGGCACGGCAACTCCACCACCATTGGGGCCGAGCGGC
GCTTCAATCCGTTCCTTGAGGGCTTGAGCCGGTGA

Upstream 100 bases:

>100_bases
ACGAAAGCACAGGCTAATCGGGGCGCCGCGACCGGTGTCAAGTGGCCCATGTTCGCGGCCCGCCTCGTCCCCGGACGCCG
GGGATGGGAAACTGGGAACC

Downstream 100 bases:

>100_bases
CGGAATTCTCGTCATTTTCGGCCCCCAAGGGGGTACCGGACTACGTCCCGCCCGACTCGGCGCAGTTCGTCGCGGTGCGC
GACGGGCTGCTCGCGGCGGC

Product: putative glyoxalase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MLITGFPAGLLACNCYVLAERPGTDAVIVDPGQGAMGTLRRILDKNRLTPAAVLLTHGHIDHIWSAQKVSDTFGCPTYVH
PADRFMLTDPIYGLGPRIAQLVAGAFFREPKQVVELDRDGDKIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFT
GDTLFERAIGRTDLAGGSGRDLLRSIVDKLLVLDDSTVVLPGHGNSTTIGAERRFNPFLEGLSR

Sequences:

>Translated_224_residues
MLITGFPAGLLACNCYVLAERPGTDAVIVDPGQGAMGTLRRILDKNRLTPAAVLLTHGHIDHIWSAQKVSDTFGCPTYVH
PADRFMLTDPIYGLGPRIAQLVAGAFFREPKQVVELDRDGDKIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFT
GDTLFERAIGRTDLAGGSGRDLLRSIVDKLLVLDDSTVVLPGHGNSTTIGAERRFNPFLEGLSR
>Mature_224_residues
MLITGFPAGLLACNCYVLAERPGTDAVIVDPGQGAMGTLRRILDKNRLTPAAVLLTHGHIDHIWSAQKVSDTFGCPTYVH
PADRFMLTDPIYGLGPRIAQLVAGAFFREPKQVVELDRDGDKIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFT
GDTLFERAIGRTDLAGGSGRDLLRSIVDKLLVLDDSTVVLPGHGNSTTIGAERRFNPFLEGLSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family

Homologues:

Organism=Escherichia coli, GI1787158, Length=218, Percent_Identity=34.4036697247706, Blast_Score=116, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17538952, Length=151, Percent_Identity=31.7880794701987, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221330176, Length=211, Percent_Identity=27.0142180094787, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356335, Length=240, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24667711, Length=240, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24667703, Length=188, Percent_Identity=26.063829787234, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2581_MYCTU (P64261)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   D70725
- RefSeq:   NP_217097.1
- RefSeq:   NP_337157.1
- ProteinModelPortal:   P64261
- SMR:   P64261
- EnsemblBacteria:   EBMYCT00000000167
- EnsemblBacteria:   EBMYCT00000071242
- GeneID:   888217
- GeneID:   925651
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2658
- KEGG:   mtu:Rv2581c
- TIGR:   MT2658
- TubercuList:   Rv2581c
- GeneTree:   EBGT00050000015466
- HOGENOM:   HBG753931
- OMA:   CVIFDPG
- ProtClustDB:   CLSK872078
- InterPro:   IPR001279
- SMART:   SM00849

Pfam domain/function: PF00753 Lactamase_B

EC number: NA

Molecular weight: Translated: 24198; Mature: 24198

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLITGFPAGLLACNCYVLAERPGTDAVIVDPGQGAMGTLRRILDKNRLTPAAVLLTHGHI
CEECCCCHHHHHEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHEEEECCCH
DHIWSAQKVSDTFGCPTYVHPADRFMLTDPIYGLGPRIAQLVAGAFFREPKQVVELDRDG
HHHHCHHHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCC
DKIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGR
CEEEECEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCCCH
DLLRSIVDKLLVLDDSTVVLPGHGNSTTIGAERRFNPFLEGLSR
HHHHHHHHHHEEECCCEEEEECCCCCCEECCHHCCCHHHHHHCC
>Mature Secondary Structure
MLITGFPAGLLACNCYVLAERPGTDAVIVDPGQGAMGTLRRILDKNRLTPAAVLLTHGHI
CEECCCCHHHHHEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHEEEECCCH
DHIWSAQKVSDTFGCPTYVHPADRFMLTDPIYGLGPRIAQLVAGAFFREPKQVVELDRDG
HHHHCHHHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCC
DKIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGR
CEEEECEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCCCH
DLLRSIVDKLLVLDDSTVVLPGHGNSTTIGAERRFNPFLEGLSR
HHHHHHHHHHEEECCCEEEEECCCCCCEECCHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036