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The map label for this gene is 121638447

Identifier: 121638447

GI number: 121638447

Start: 2846740

End: 2847789

Strand: Direct

Name: 121638447

Synonym: BCG_2585

Alternate gene names: NA

Gene position: 2846740-2847789 (Clockwise)

Preceding gene: 121638446

Following gene: 121638448

Centisome position: 65.08

GC content: 64.67

Gene sequence:

>1050_bases
ATGCTTTTTGCGGCTTTGCGTGATGTCCAATGGCGAAAACGACGCCTTGTCATCGCAATCGTCAGCACCGGCCTAGTTTT
CGCGATGACGCTCGTTCTGACCGGACTTGTGAACGGGTTTCGGGTCGAGGCCGAGCGAACCGTCGATTCCATGGGTGTCG
ACGCATTCGTGGTCAAGGCCGGCGCGGCAGGACCGTTCCTGGGTTCGACACCATTCGCCCAAATCGACCTGCCCCAGGTT
GCTCGTGCGCCTGGCGTCTTGGCTGCCGCCCCACTAGCGACTGCGCCGTCGACGATCCGGCAGGGCACGTCAGCGCGAAA
CGTCACCGCGTTCGGGGCACCAGAGCACGGACCCGGCATGCCGCGGGTCTCGGACGGTCGGGCGCCATCGACGCCGGACG
AGGTCGCGGTGTCGAGCACGCTGGGCCGAAACCTCGGCGACGATCTGCAAGTGGGTGCGCGCACTTTGCGGATCGTCGGC
ATCGTGCCCGAGTCAACCGCGCTGGCAAAGATTCCCAACATCTTCCTGACCACCGAAGGCCTACAGCAGTTGGCATACAA
CGGACAGCCGACAATCAGTTCGATCGGGATCGACGGGATGCCCCGACAGCTCCCGGACGGCTATCAGACCGTCAATCGAG
CGGATGCTGTCAGCGATCTGATGCGCCCGTTGAAGGTCGCGGTGGATGCGATCACGGTTGTGGCGGTCTTGCTGTGGATC
GTTGCGGCGTTGATCGTCGGCTCGGTGGTCTACCTCTCTGCGTTGGAGCGGCTGCGTGACTTTGCGGTGTTCAAGGCGAT
CGGCGTGCCGACGCGCTCGATTCTGGCCGGGCTGGCGCTGCAGGCGGTCGTCGTCGCGCTGCTCGCGGCGGTGGTTGGCG
GCATCCTTTCGCTGCTGTTGGCGCCGTTGTTCCCGATGACTGTCGTGGTACCCCTGAGTGCCTTCGTGGCGCTACCGGCG
ATCGCGACTGTGATCGGTCTGCTGGCCAGCGTCGCAGGACTGCGGCGCGTGGTGGCGATCGATCCGGCACTAGCGTTCGG
AGGTCCCTAG

Upstream 100 bases:

>100_bases
GACCGACCCCCTCACCTCGGTCGAACCTCGGCGAACCAACGCGGCAACGCCAGCCCATGATCATTTGATTGGGTCCACGG
AAGCAGGTAGCTTCCGTCGC

Downstream 100 bases:

>100_bases
CCATGGGCGGCCTAACCATTTCCGACCTGGTCGTCGAGTATTCCAGCGGCGGGTACGCCGTGCGGCCGATCGACGGGTTA
AGCCTCGACGTGGCGCCGGG

Product: putative glutamine-transport transmembrane protein ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MLFAALRDVQWRKRRLVIAIVSTGLVFAMTLVLTGLVNGFRVEAERTVDSMGVDAFVVKAGAAGPFLGSTPFAQIDLPQV
ARAPGVLAAAPLATAPSTIRQGTSARNVTAFGAPEHGPGMPRVSDGRAPSTPDEVAVSSTLGRNLGDDLQVGARTLRIVG
IVPESTALAKIPNIFLTTEGLQQLAYNGQPTISSIGIDGMPRQLPDGYQTVNRADAVSDLMRPLKVAVDAITVVAVLLWI
VAALIVGSVVYLSALERLRDFAVFKAIGVPTRSILAGLALQAVVVALLAAVVGGILSLLLAPLFPMTVVVPLSAFVALPA
IATVIGLLASVAGLRRVVAIDPALAFGGP

Sequences:

>Translated_349_residues
MLFAALRDVQWRKRRLVIAIVSTGLVFAMTLVLTGLVNGFRVEAERTVDSMGVDAFVVKAGAAGPFLGSTPFAQIDLPQV
ARAPGVLAAAPLATAPSTIRQGTSARNVTAFGAPEHGPGMPRVSDGRAPSTPDEVAVSSTLGRNLGDDLQVGARTLRIVG
IVPESTALAKIPNIFLTTEGLQQLAYNGQPTISSIGIDGMPRQLPDGYQTVNRADAVSDLMRPLKVAVDAITVVAVLLWI
VAALIVGSVVYLSALERLRDFAVFKAIGVPTRSILAGLALQAVVVALLAAVVGGILSLLLAPLFPMTVVVPLSAFVALPA
IATVIGLLASVAGLRRVVAIDPALAFGGP
>Mature_349_residues
MLFAALRDVQWRKRRLVIAIVSTGLVFAMTLVLTGLVNGFRVEAERTVDSMGVDAFVVKAGAAGPFLGSTPFAQIDLPQV
ARAPGVLAAAPLATAPSTIRQGTSARNVTAFGAPEHGPGMPRVSDGRAPSTPDEVAVSSTLGRNLGDDLQVGARTLRIVG
IVPESTALAKIPNIFLTTEGLQQLAYNGQPTISSIGIDGMPRQLPDGYQTVNRADAVSDLMRPLKVAVDAITVVAVLLWI
VAALIVGSVVYLSALERLRDFAVFKAIGVPTRSILAGLALQAVVVALLAAVVGGILSLLLAPLFPMTVVVPLSAFVALPA
IATVIGLLASVAGLRRVVAIDPALAFGGP

Specific function: Unknown

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2563_MYCTU (P65007)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   G70728
- RefSeq:   NP_217079.1
- RefSeq:   NP_337138.1
- EnsemblBacteria:   EBMYCT00000001524
- EnsemblBacteria:   EBMYCT00000071871
- GeneID:   887516
- GeneID:   925676
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2639
- KEGG:   mtu:Rv2563
- TIGR:   MT2639
- TubercuList:   Rv2563
- GeneTree:   EBGT00050000016172
- HOGENOM:   HBG569186
- OMA:   SEIGILK
- ProtClustDB:   CLSK790237
- GO:   GO:0006810
- InterPro:   IPR003838

Pfam domain/function: PF02687 FtsX

EC number: NA

Molecular weight: Translated: 36026; Mature: 36026

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x175925f4)-; HASH(0x17a44efc)-; HASH(0x176957d0)-; HASH(0x17d4981c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFAALRDVQWRKRRLVIAIVSTGLVFAMTLVLTGLVNGFRVEAERTVDSMGVDAFVVKA
CCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCEEEEEC
GAAGPFLGSTPFAQIDLPQVARAPGVLAAAPLATAPSTIRQGTSARNVTAFGAPEHGPGM
CCCCCCCCCCCCCCCCCHHHHCCCCCCEECCCCCCCHHHHCCCCCCCEEEECCCCCCCCC
PRVSDGRAPSTPDEVAVSSTLGRNLGDDLQVGARTLRIVGIVPESTALAKIPNIFLTTEG
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEEECCCCHHHHHCCCCEEEHHH
LQQLAYNGQPTISSIGIDGMPRQLPDGYQTVNRADAVSDLMRPLKVAVDAITVVAVLLWI
HHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAALIVGSVVYLSALERLRDFAVFKAIGVPTRSILAGLALQAVVVALLAAVVGGILSLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APLFPMTVVVPLSAFVALPAIATVIGLLASVAGLRRVVAIDPALAFGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCH
>Mature Secondary Structure
MLFAALRDVQWRKRRLVIAIVSTGLVFAMTLVLTGLVNGFRVEAERTVDSMGVDAFVVKA
CCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCEEEEEC
GAAGPFLGSTPFAQIDLPQVARAPGVLAAAPLATAPSTIRQGTSARNVTAFGAPEHGPGM
CCCCCCCCCCCCCCCCCHHHHCCCCCCEECCCCCCCHHHHCCCCCCCEEEECCCCCCCCC
PRVSDGRAPSTPDEVAVSSTLGRNLGDDLQVGARTLRIVGIVPESTALAKIPNIFLTTEG
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEEECCCCHHHHHCCCCEEEHHH
LQQLAYNGQPTISSIGIDGMPRQLPDGYQTVNRADAVSDLMRPLKVAVDAITVVAVLLWI
HHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAALIVGSVVYLSALERLRDFAVFKAIGVPTRSILAGLALQAVVVALLAAVVGGILSLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APLFPMTVVVPLSAFVALPAIATVIGLLASVAGLRRVVAIDPALAFGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036